2023年上海市金山区食源性疾病监测及致病菌耐药性分析

Foodborne diseases surveillance and analysis of drug resistance of pathogenic bacteria in Jinshan District of Shanghai in 2023

中文关键词:  食源性疾病  监测  病原体  药敏实验  抗生素  耐药性

英文关键词:foodborne diseases  surveillance  pathogens  drug susceptibility test  antibiotics  drug resistance

中文摘要:

      目的 探究上海市金山区食源性疾病病例及致病病原体流行病学特征和耐药情况。方法 2023年监测金山区15家哨点医疗机构食源性疾病病例信息并对患者粪便样本中的阳性菌株进行复核、分型鉴定和药敏实验。结果 2023年金山区共报告食源性疾病病例408例, 男女性别比5:4, 以18~34岁者最多, 职业以工人、民工、农民为主, 以5—9月高发, 可疑暴露食品除多种及混合食品外, 以蔬菜水果类占比较高。致病菌检出率为21.46% (47/219), 以致泻大肠埃希氏菌为主, 诺如病毒为18.72% (41/219)。药敏结果中沙门氏菌多重耐药菌株占比达83.33% (10/12)。结论 2023年金山区食源性疾病监测中诺如病毒和致泻大肠埃希菌为主要致病病原体, 致病菌中沙门氏菌和致泻大肠埃希菌均有不同程度耐药, 需继续加强食源性疾病监测, 同时相关部门应加强抗生素耐药科普和各类抗生素管理、合理使用和敏感检测。

英文摘要:

      Objective To investigate the epidemiological characteristics and drug resistance of foodborne disease cases and pathogens in Jinshan District of Shanghai. Methods The case information of foodborne diseases in 15 sentinel medical institutions in Jinshan District was monitored in 2023, and the positive bacteria in the stool samples of patients were rechecked, identified, and tested for drug sensitivity. Results In 2023, a total of 408 cases of foodborne diseases were reported in Jinshan District, the male to female ratio was 5:4, most of them were 18–34 years old, the occupation was mainly workers, migrant workers and farmers, and the incidence was high from May to September. Except for multiple and mixed foods, vegetables and fruits accounted for a relatively high proportion in suspicious exposed foods. The detection rate of pathogenic bacteria was 21.46% (47/219), diarrheagenic Escherichia coli was the main pathogen, and norovirus was 18.72% (41/219). The results of drug sensitivity showed that the proportion of multi-drug resistant strains in Salmonella was 83.33% (10/12). Conclusion In the 2023 foodborne disease surveillance in Jinshan District, norovirus and diarrheagenic Escherichia coli are the main pathogenic agents. Among the pathogenic bacteria, both Salmonella and diarrheagenic Escherichia coli shows varying degrees of drug resistance. It is necessary to continue strengthening the monitoring of foodborne diseases. Meanwhile, relevant departments shall enhance public awareness of antibiotic resistance, and strengthen the management, rational use and sensitivity testing of various antibiotics.