红芪多糖提取、分离纯化及药理作用研究进展

Research progress on extraction, separation purification and pharmacological effects of polysaccharides from Hedysari radix

中文关键词:  红芪  多糖  提取  分离纯化  药理作用

英文关键词:Hedysari radix  polysaccharides  extraction  separation and purification  pharmacological effects

中文摘要:

      红芪作为甘肃的大宗药材, 以“米仓红芪”为佳, 主要含有红芪多糖类、黄酮类、苯丙素类、生物碱类、有机酸类等化学成分。大量研究表明, 红芪多糖是红芪药材主要活性成分之一, 具有抗炎、抗肿瘤、抗氧化、免疫调节等多种药理作用, 在医药保健、食品等领域有良好的应用前景。本文通过文献检索, 梳理并总结近10年国内外红芪多糖的提取、分离纯化以及药理活性研究, 通过阐述红芪多糖提取工艺、含量测定方法的优缺点, 总结红芪多糖的单糖组成、结构特征, 分析红芪多糖研究的发展趋势, 为红芪多糖的进一步研究和开发利用提供一定参考依据。

英文摘要:

      Hongqi (Hedysari radix) is a major medicinal material in Gansu Province, with “Mi Cang Hong Qi” as the best. It mainly contains Hedysarum polysaccharides, flavonoids, phenylpropanoids, alkaloids, organic acids and other chemical components. Lots of research shows that polysaccharide is one of the main active components of Hedysari radix. Hedysarum polysaccharides as one of the main active components of Hedysari radix has multiple pharmacological effects, such as, anti-inflammatory, anti-tumor, antioxidant, and immunomodulatory activities and has good application in medicine health care food and other fields. Through literature retrieval, this paper combed and summarized the research on extraction, separation and purification and pharmacological activities of Hedysarum polysaccharides at home and abroad in recent 10 years. Through expounding the advantages and disadvantages of extraction technology and content determination methods of Hedysarum polysaccharides, this paper summarized the monosaccharide composition and structural characteristics of Hedysarum polysaccharides, analyzed the development trend of Hedysarum polysaccharides research, and provided certain reference for further research, development and utilization of Hedysarum polysaccharides.