50%异菌脲·腐霉利悬浮剂在设施和露地番茄上的残留与安全性评价

Residue and safety evaluation of 50% iprodione and procymidone suspension on greenhouse and open field tomatoes

中文关键词:  异菌脲  腐霉利  番茄  超高效液相色谱-串联质谱法  农药残留

英文关键词:iprodione  procymidone  tomatoes  ultra performance liquid chromatography-tandem mass spectrometry  pesticide residue

中文摘要:

      目的 开展50%异菌脲·腐霉利悬浮剂在设施和露地番茄上的残留试验, 评价其在番茄上使用的安全性。方法 2021年在北京、辽宁、甘肃、山西、山东、浙江、河南、江苏、贵州、河北、湖南和重庆的番茄主产区开展了田间试验, 番茄样品用乙腈涡旋提取, N-丙基乙二胺、石墨化碳黑和十八烷基碳混合分散吸附剂净化, 超高效液相色谱分离, 三重四极杆串联质谱检测, 基质标准曲线-外标法定量。结果 设施番茄中异菌脲和腐霉利的降解半衰期分别为11.5和12.3 d, 露地番茄中异菌脲和腐霉利的降解半衰期分别为6.9和7.8 d。50%异菌脲·腐霉利悬浮剂在番茄上按最高剂量525 g a.i/hm2施药3次后, 安全间隔期7 d时, 设施番茄中异菌脲的最终残留量为0.10~0.73 mg/kg, 腐霉利的最终残留量为0.14~1.67 mg/kg, 露地番茄中异菌脲的最终残留量为<0.01~0.25 mg/kg, 腐霉利的最终残留量为<0.01~0.58 mg/kg。结论 依据GB 2763—2021《食品安全国家标准 食品中农药最大残留限量》中规定的异菌脲和腐霉利的最大残留限量标准, 收获的番茄食用是安全的。本研究结果为50%异菌脲·腐霉利悬浮剂在设施和露地番茄上的安全使用、农药残留量控制和农产品安全提供理论和技术支持。

英文摘要:

      Objective To investigate the residual levels and evaluate the residue safety of 50% iprodione and procymidone suspension on tomatoes, carry out the greenhouse test and field test. Methods Field experiments were conducted in the main tomato producing areas in Beijing, Liaoning, Gansu, Shanxi, Shandong, Zhejiang, Henan, Jiangsu, Guizhou, Hebei, Hunan and Chongqing in 2021, the tomato samples were vortex extracted with acetonitrile, purified with the mixed and dispersed adsorbent of N-propylethylenediamine, graphitized carbon black and octadecyl carbon, separated by ultra performance liquid chromatography, detected by triple quadrupole tandem mass spectrometry, and quantified by the matrix standard curve-external standard method. Results The degradation half-lives of iprodione and procymidone in greenhouse tomatoes were 11.5 and 12.3 d, respectively, and those of iprodione and procymidone in open field tomatoes were 6.9 and 7.8 d, respectively. After the maximum dose of 50% iprodione and procymidone suspension was applied to tomatoes for 3 times at the highest dose of 525 g a.i/hm2, and when the safety interval was 7 d, the final residual amount of iprodione in greenhouse tomato was 0.10?0.73 mg/kg, the final residual amount of procymidone was 0.14?1.67 mg/kg, and the final residual amount of iprodione in open field tomato was <0.01?0.25 mg/kg, the final residue of procymidone was <0.01?0.58 mg/kg. Conclusion According to GB 2763—2021 National food safety standard-Maximum residue limit of pesticides in food, the harvested tomatoes are safe to eat. The results of this study provide theoretical and technical support for the safe use, pesticide residue control and agricultural product safety of 50% iprodione and procymidone suspension on greenhouse and open field tomatoes.