药膳中芦丁的吸收利用与护肝健康功效研究进展

Research progress on the absorption and utilization of rutin in medicinal diet and its effects of protecting liver and health

中文关键词:  药膳  芦丁  代谢  肠道吸收  护肝

英文关键词:medicinal diet  rutin  metabolism  intestinal absorption  liver protective

中文摘要:

      肝脏是机体代谢、营养运输和排毒解毒的重要器官, 对维持机体健康起着重大作用。目前, 由于快节奏生活方式、不良生活习惯或外源应激导致肝疾病患者的人数日益增长, 严重影响人们的生活质量。芦丁是一种常见于药膳植物中的黄酮类化合物, 因其安全且具有良好的护肝等生物活性备受关注。但黄酮类化合物很难被机体直接吸收用于保护肝脏, 需经肠道代谢后才能被机体吸收发挥其生物活性。目前关于芦丁活性的研究论文和综述报道不少, 但近20年来鲜有文章系统地回顾有关芦丁的代谢、吸收与护肝作用机制之间的联系。本文以“芦丁”“肠”和“肝”为关键词, 通过检索国内外专业学术网站, 重点归纳总结了芦丁的代谢、吸收与利用途径, 以及芦丁在护肝健康功效作用方面的相关研究进展, 并进行了展望, 以期为将来芦丁的护肝功能食品的开发提供科学依据。

英文摘要:

      The liver is an important organ of metabolism, nutrition transport, detoxification and detoxification, which plays an important role in maintaining the health of the body. At present, the number of patients with liver disease caused by fast-paced lifestyle, bad living habits or exogenous stress is increasing, which seriously affects people’s quality of life. Rutin is a flavonoid commonly found in medicinal plants, and it has attracted much attention because of its safety and good liver protection and other biological activities. However, flavonoids are difficult to be directly absorbed by the body to protect the liver, and need to be metabolized by the intestinal tract before they can be absorbed by the body to exert their biological activity. At present, there are many research papers and reviews on the activity of rutin, but few articles have systematically reviewed the relationship between the metabolism, absorption and liver protection mechanism of rutin in the past 20 years. Taking “rutin” “intestine” and “liver” as key words, this paper summarized and prospected the metabolism, absorption and utilization of rutin and the effects of rutin on liver protection by searching professional academic websites at home and abroad, in order to provide scientific data for the development of liver protection products of rutin in the future.