海藻有机碘检测方法的研究进展

Research progress on the detection methods of organic iodine in seaweed

中文关键词:  海藻  3-碘-L-酪氨酸  L-3,5-二碘酪氨酸

英文关键词:seaweed  3-iodo-L-tyrosine  L-3,5-diiodotyrosine

中文摘要:

      碘是人类所必需的微量矿物质元素, 与健康息息相关。食物中的碘以碘化物的形式进入人体甲状腺, 先与甲状腺球蛋白中的酪氨酸形成碘酪氨酸, 然后参与形成甲状腺激素, 维持人体甲状腺的正常功能。研究发现高碘甲状腺肿和无机碘过敏患者对有机碘的吸收利用率比无机碘高, 这些特性使富含有机碘的海藻受到较多关注。目前用于海藻中有机碘的提取方法主要有溶剂萃取法(包括酸提取法和碱提取法)、微波辅助碱性提取法、酶提取法、几种方法结合的提取方法、新兴的提取方法(包括两性表面活性剂萃取法、离子液体萃取法、基质固相分散萃取法)等。有机碘的检测方法主要有高效液相色谱法、电感耦合等离子体质谱法、液相色谱-质谱联用法以及新兴检测方法等。本文综述了现阶段海藻中有机碘提取方法和检测方法的优点和缺点, 以期为海藻有机碘的科学检测方法的建立提供理论依据。

英文摘要:

      Iodine is an essential microelement and closely related to human health. When ingesting from food, iodine is transported into the thyroid gland as iodide. After binding with tyrosine in thymoglobulin and formingiodo tyrosine’s, iodine participates in the formation of thyroid hormone and maintains the normal function of the thyroid. Compared with inorganic iodine, organic iodine is absorbed and utilized easily by patients with iodine excess goiter or inorganic iodine allergy. As an abundant source of organic iodine, seaweed has been widely studied for years. At present, main extraction methods for organic iodine in seaweed include solvent extraction methods (acid and basic solution extractions), microwave assisted alkaline digestion, enzyme extraction, integration of aforementioned methods, and novel methods, such as zwitterionic surfactant, ionic liquids and matrix solid-phase dispersion. Detection methods of organic iodine mainly include high performance liquid chromatography, inductively coupled plasma-mass spectrometry, and high performance liquid chromatography- mass spectrometry. This paper reviewed the advantages and disadvantages of organic iodine extraction and detection methods in algae, in order to provide a theoretical basis for the establishment of a scientific method for the determination of organic iodine in algae.