分子印迹技术在食品样品安全分析中的应用

Application of molecular imprinting technology in safety analysis of food samples

中文关键词:  分子印迹技术  食品安全分析  样品前处理

英文关键词:molecular imprinting technology  food safety analysis  sample preparation

中文摘要:

      食品基质复杂多样, 食品中相关物质检测的准确性很大程度上依赖于食品的前处理, 如何通过食品的前处理提高方法的选择性和特异性是食品检测的关键。分子印迹聚合物(molecularly imprinted polymers, MIPs)是一种可特异性识别靶标物质的聚合物, 由模板分子和功能单体形成的络合物与致孔剂共聚合, 再去除模板, 形成与目标物在形状、大小、官能团和空间排列上互补的空间结构和结合位点, 由于其亲和力和选择性较强, 目前已经广泛应用于食品样品的前处理过程中。本文介绍了MIPs的主要制备方法, 综述了基于分子印迹技术的固相萃取、固相微萃取、搅拌棒吸附萃取和基质固相分散萃取在食品样品前处理中的最新应用进展, 总结了目前MIPs在食品样品前处理过程中存在的问题以及未来的发展方向和趋势。

英文摘要:

      The accuracy of food samples test has a large extent relying on sample preparation due to the complexity and variety matrix of foods, which is also the key in food tests to promote the selectivity and specificity of test. Molecularly imprinted polymers (MIPs) are kinds of specific polymer to recognize the target substances in foods, which are complex formed by template molecules and functional monomer to the pore copolymerization. After removal of the template, the reaction materials are formed spatial structure and binding site complementary to the target in shape, size, functional group, and spatial arrangement. Due to their strong affinity and selectivity, these kinds of materials have been widely used in the process of food sample preparation. This paper introduced the main preparation methods of MIPs, reviewed the recent progress of the multiple techniques around the latest applications in food sample preparation progress based on molecular imprinting techniques, such as solid phase extraction, solid phase microextraction, stir bar sorptive extraction, and matrix solid-phase dispersion extraction, and summed up the existing problems and the development trend in future about MIPs in food sample preparation.