铁皮石斛对大鼠血液生化指标影响的研究

Effects of Dendrobium officinale on blood biochemical indexes of rats

中文关键词:  铁皮石斛  大鼠  90 d喂养  血生化指标

英文关键词:Dendrobium officinale  rats  90 days feeding  blood biochemical indexes

中文摘要:

      目的 探讨铁皮石斛对大鼠血液生化指标的影响。方法 采用拌饲法连续喂养大鼠90 d后, 观察试验动物一般生长情况, 测试谷草转氨酶、谷丙转氨酶、胆固醇、甘油三酯等血生化指标。结果 各剂量组大鼠体重、增重、进食量及食物利用率均正常。大鼠谷丙转氨酶出现降低, 雄性大鼠受试组与对照组比较有统计学差异(P＜0.01)。中、高剂量组雄性大鼠胆固醇降低, 与对照组比较, 在统计学上有显著性差异(P＜0.01); 与对照组比较, 低、中剂量组雌性大鼠胆固醇出现降低, 在统计学上有显著性差异(P＜0.05)。结论 铁皮石斛具有降低受试动物大鼠谷丙转氨酶和胆固醇的作用。

英文摘要:

      Objective To investigate the effects of Dendrobium officinale on blood biochemical indexes of rats. Methods After the rats were continuously fed with mixed feeding method for 90 d, the general growth conditions of the experimental animals were observed, and blood biochemical indexes such as glutamic oxaloacetic transaminase (AST), alanine transaminase (ALT), cholesterol (TC) and triglyceride (TG) were tested. Results The body weight, weight gain, food intake and food utilization rate of rats in each dose group were normal. The results showed that the ALT in male rats decreased and there was a significant difference between the experimental group and the control group (P<0.01). Compared with the control group, the TC of male rats in the middle and high dose groups decreased significantly (P<0.01). Compared with the control group, the TC of female rats in the low and middle dose groups decreased significantly (P<0.05). Conclusion Dendrobium officinale has the effect of reducing ALT and TC in rats.