2015-2016年河北省腹泻散发病例中诺如病毒感染的流行病学特征分析

Analysis on the epidemiological characteristics of norovirus diarrhea in Hebei province in 2015-2016

中文关键词:  诺如病毒  腹泻  流行病学

英文关键词:norovirus  acute diarrhea  epidemiology

中文摘要:

      目的 了解2015?2016年河北省腹泻散发病例中诺如病毒感染的流行病学特征。方法 收集2015年9月~2016年12月河北省部分医院肠道门诊腹泻病例便样本及流行病学相关资料, 采用RT-PCR方法检测诺如病毒并进行数据分析。结果 在1240样本中, 诺如病毒阳性58份, 阳性率为4.68%; 诺如病毒阳性率存在地域差异, 邢台地区阳性率最高为10.08%; 全年均有散发病例但在冬春季节出现明显的发病高峰; 基因型以GⅡ型为主(4.28%), GI型阳性率0.40%; 易感人群为婴幼儿(0~6岁)和老年组(66~), 其感染不存在性别差异。结论 诺如病毒是河北省散发感染性腹泻的重要病原, 应加强对诺如病毒的监测, 并进一步研究其变异, 为诺如病毒感染的预防和控制提供科学的依据。

英文摘要:

      Objective To understand the epidemiological characteristics of norovirus infection in sporadic diarrhea cases in Hebei province in 2015?2016. Methods The diarrhea stool samples and epidemiological related data from September 2015 to December 2016 in the intestinal clinic were collected, and norovirus was detected and classified by RT-PCR. Results A total of 58 (4.68%) positive specimens were detected among 1240 sporadic cases of acute diarrhea; the positive rate of norovirus varied by region, and the highest positive rate of Xingtai was 10.08%. There were sporadic cases throughout the year, but there were obvious peak in winter and spring. The genotype was mainly GⅡtype (4.28%), GI type positive rate was 0.40%. The susceptible population was infants (0~6) and the elderly group (66~), and there was no difference infection in gender. Conclusion Norovirus is an important pathogen of infections diarrhea in Hebei province. The monitoring of norovirus should be strengthened, and its variation should be further studied to provide a scientific basis for the prevention and control of norovirus infection.