食品安全风险检测中电喷雾电离源的应用及基质效应的应对方法

Application of electrospray ionization source in food safety risk detection and solution of matrix effect

中文关键词:  食品污染物  非法添加  风险监测  基质效应  液相色谱质谱仪  电喷雾电离源

英文关键词:food contaminants  illegal addition  risk monitoring  matrix effect  liquid chromatography mass spectrometer  electrospray ionization source

中文摘要:

      电喷雾电离源(electrospray ionization, ESI)既是液相色谱和质谱仪之间的连接装置, 同时又是电离装置, 是目前最常用的质谱仪离子源。ESI源的应用十分广泛, 特别在食品安全检测领域。基质效应是ESI源使用过程中无法避免的问题, 特别在基质复杂的食品样品中。本文研究了《2018年国家食品污染物和有害因素风险监测工作手册(中卷)》(有机污染物领域), 根据仪器类型、离子源、定量方式进行分类统计分析, 探讨食品安全风险检测中基质效应应对方法, 并对ESI源在食品安全风险检测中的应用进行了展望, 以期为食品安全风险检测的技术人员提供参考。

英文摘要:

      Electrospray ionization (ESI) is not only the connection between liquid chromatography and mass spectrometry, but also the ionization device. It is the most commonly used mass spectrometer ion source. The ESI source is widely used, especially in the field of food safety testing. Matrix effects are an unavoidable problem in the use of ESI sources, especially in food samples with complex matrices. This paper studied the National Food Contaminants and Hazardous Factors Risk Monitoring Manual (Vol. 2) in the 2018 (organic pollutants field). According to the type of instrument, ion source and quantitative method, the classification and statistical analysis were carried out to explore the method of matrix effect in food safety risk detection, and the application of ESI source in food safety risk detection was prospected, in order to provide a reference for technicians in food safety risk testing.