生鲜食品中诺如病毒污染与作用受体的研究进展

Research progress of norovirus contamination and its binging receptors in fresh food

中文关键词:  生鲜食品  诺如病毒  污染  作用受体

英文关键词:fresh food  noroviruses  contamination  binging receptors

中文摘要:

      诺如病毒(noroviruses, NoVs)是世界范围内引起非细菌性急性胃肠炎疫情爆发的主要病原体。组织血型抗原(histo-blood group antigens, HBGAs)作为NoVs的作用受体, 在NoVs的传播中起着极其重要的作用。果蔬产品在从农场到餐桌这一供应链的任何环节均有可能被NoVs污染, 已成为传播NoVs的高风险食品。海产贝类作为NoVs的另一重要传播媒介, 主要通过滤食作用富集NoVs。 部分生鲜食品内也存在类HBGAs与NoVs特异结合, 使存在于生鲜食品内的NoVs难以被净化。本文主要综述了NoVs在生鲜食品中的蓄积、分布、污染来源及其作用受体的研究进展。

英文摘要:

      Noroviruses (NoVs) are the leading etiological agents of causing the worldwide epidemic outbreak of acute epidemic non-bacterial gastroenteritis. Histo-blood group antigens (HBGAs) are considered as receptors of NoVs, which play a critical role in infection of NoVs. Fruits and vegetables are likely contaminated by NoVs in any link of the supply chain from the farm to the table, which become the high-risk food products spreading NoVs. Besides, marine shellfishes are another important communication media of NoVs, which mostly enrich NoVs by filter-feeding. Further studies indicated that there were some combinations of HBGAs-like and NoVs in fresh food which made NoVs in this kind of food difficult to be purified. This paper mainly reviewed the research advances of the accumulation, distribution, pollution sources and binding receptors of NoVs in fresh food.