2013~2015年湖北地区虾中硝基呋喃代谢物残留的监测分析

Monitoring and analysis of nitrofuran metabolites residues in shrimp of Hubei area in 2013~2015

中文关键词:  虾  硝基呋喃  代谢物  残留监测

英文关键词:shrimp  nitrofuran  metabolite  residue monitoring

中文摘要:

      目的 分析2013~2015年湖北地区虾产品中硝基呋喃类药物的残留情况, 以期为硝基呋喃代谢物的来源和危害分析提供科学依据。方法 采用超高效液相色谱串联质谱法检测湖北虾产品中呋喃它酮(furaltadone)、呋喃西林(nitrofurazone)、呋喃妥因(nitrofurantoin)和呋喃唑酮(furazolidone)4种硝基呋喃类代谢物的残留量, 并用Excel和SPSS 16.0对实验数据进行统计学分析。结果 硝基呋喃类药物的代谢产物总体检出率为27.09%, 检出的代谢物均为氨基脲(semi carbazide, SEM), 河虾的检出率最高, 为61.54%; 其次是基围虾为6.78%; 最低是小龙虾为1.38%; 对于整体匀浆的带壳河虾样品, 检出率高达91.67%; 而去壳的河虾虾肉样品没有检出SEM。结论 湖北地区的虾产品中存在不同程度的硝基呋喃污染情况, 同时发现河虾中有内源性SEM的存在。结合湖北地区居民的膳食消费情况分析, 虾中SEM暴露对人类健康危害较小。

英文摘要:

      Objective To analyze the nitrofuran metabolites residues in shrimp of Hubei area in 2013~2015, so as to provide scientific basis for the source and hazard analysis. Methods The residues of 4 kinds of nitrofuran metabolites including furaltadone, nitrofurazone, nitrofurantoin and furazolidone in shrimp of Hubei area were detected by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), and the obtained data were statistically analyzed by Excel and SPSS16.0. Results The detection rate of nitrofuran metabolites was 27.09%, and all of them were semi carbazide (SEM), while river prawn had the highest detection rate of 61.54%, followed by shrimps of 6.78% and crawfish of 1.38%. For overall homogenate river shrimp, the detection rate was up to 91.67%, while SEM was not detected in the shelled shrimp samples. Conclusion Different levels of SEM are detected in shrimp of Hubei area, meanwhile endogenous SEM is founded in river prawn. According to the food consumption data of residents in Hubei area, the SEM exposure in shrimp is less harmful to human health.