以香菇柄为主料固态发酵血芝提取液的抗氧化活性研究

Antioxidant activity of Amauroderma rudis-roots of Lentinus solid fermentation compounds

中文关键词:  血芝  香菇柄  固态发酵  抗氧化

英文关键词:Amauroderma rudis  roots of Lentinus  solid fermentation  antioxidant

中文摘要:

      目的 探讨血芝-香菇柄固态发酵复合物提取液的抗氧化作用。方法 体内抗氧化试验, 将50只昆明种小鼠随机分为5个组, 分别为空白对照组、阳性对照组、低剂量组(2.5 g/kg)、中剂量组(5 g/kg)和高剂量组(10 g/kg)。灌胃30 d后, 采样, 测定小鼠血清超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)含量。 结果 小鼠血清中SOD和GSH-Px的活力随剂量的增加而增大, 且5 g/(kg?d)和10 g/(kg?d)剂量组与阳性对照组相比较, 差异性显著(P<0.05)。结论 血芝-香菇柄固态发酵提取液具有抗氧化作用。

英文摘要:

      Objective To investigate the antioxidant activity of the extract of Amauroderma rudis-roots of Lentinus solid fermentation compounds. Methods A total of 50 healthy mice were randomly divided into blank control group, positive control group, low dose group (2.5 g/kg), middle dose group (5 g/kg) and high dose group (10 g/kg). After 30 d, the content of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in serum were determined. Results The activities of SOD and GSH-Px in serum were increased with the dose increased, and the differences were significant in middle dose group and high dose group compared to positive control group (P＜0.05). Conclusion It was indicated the extract of Amauroderma rudis-roots of Lentinus solid fermentation compounds had antioxidant activity.