ω-3多不饱和脂肪酸对2型糖尿病患者 糖脂代谢的影响

Effect of ω-3 polyunsaturated fatty acids on glucose and lipid metabolism in patients with type 2 diabetes

中文关键词:  ω-3多不饱和脂肪酸  2型糖尿病  糖脂代谢

英文关键词:ω-3 polyunsaturated fatty acid  type 2 diabetes mellitus  glucose and lipid metabolism

中文摘要:

      2型糖尿病已成为当前威胁全球人类健康最重要的慢性非传染性疾病之一。2型糖尿病患者常伴有不同程度的脂代谢紊乱, 血脂异常可导致糖尿病多种并发症的发生, 最终威胁糖尿病患者的生命。近年来, ω-3多不饱和脂肪酸对心血管疾病的保护效应成为医学及营养学界关注的热点, 然而在研究不同来源ω-3多不饱和脂肪酸, 特别是植物性来源ω-3多不饱和脂肪酸对2型糖尿病患者糖脂代谢的影响方面则要落后和迟缓一些。为此, 本文综述了不同来源ω-3多不饱和脂肪酸与2型糖尿病发病风险及其对2型糖尿病患者糖脂代谢的影响, 以期为推动2型糖尿病营养治疗提供参考。

英文摘要:

      Type 2 diabetes mellitus (T2DM) is currently one of the most important chronic non-communicable diseases among global range of people. There existed significant disorder of lipid metabolism in patients with T2DM. The lipid metabolism disorder can cause multiple diabetes complications, all of which can be life threatening eventually. In recent years, the protective effects of ω-3 polyunsaturated fatty acid (PUFA) on car-diovascular disease have become a hot spot of concern among the medicine and nutrition community. However, researches in the effect of ω-3 PUFA coming from different sources, especially the plant-derived ω-3 PUFA, on glucose and lipid metabolism in population of T2DM started relatively late. This paper reviewed the relationship between risk of T2DM and ω-3 PUFA coming from different sources, as well as the effect of ω-3 PUFA on glucose and lipid metabolism in population of T2DM. The related information can serve as references of nutrition therapy for T2DM.