生物法发酵生产木糖醇研究进展

Research advances in xylitol production by biological fermentation

中文关键词:  木糖醇  菌株  发酵调控  固定化

英文关键词:xylitol  strain  fermentation control  immobilization

中文摘要:

      木糖醇作为食品, 医药, 化工等领域的重要合成原料, 具有极高的应用价值。利用微生物法发酵生产木糖醇具有原料来源广泛, 发酵条件温和，产物分离纯化简单等优势, 一直被认为是绿色经济的木糖醇生产工艺路线。本文通过对生物法生产木糖醇的热点问题: 发酵菌种的分类和发酵性能、基因工程菌的改造策略、以半纤维素水解液为发酵底物的制取、脱毒处理和发酵条件优化以及在固定化技术中所应用到的载体和固定化方法等几个方面进行梳理和归纳, 系统阐述了生物法发酵生产木糖醇的最新研究进展, 并对其前景进行了展望。

英文摘要:

      Xylitol, as the important synthetic materials in food, medicine, chemical industry and other fields, has a high application value. The microbial methods of xylitol production have some obvious advantages, such as the wide raw material sources, moderate fermentation condition, simple and convenient way to separation. Therefore, it has been regarded as a green economy route of xylitol production. This paper aimed to summarize some aspects of biological fermentation in xylitol production. It included the classification and performance of fermentation strains, the transformation strategy of genetic engineering bacteria, the preparation and detoxification of hemicellulose hydrolysate, the optimization of fermentation from hydrolysate, and the carrier and methods of immobilization technology. The advanced researches of biological methods for xylitol production were elaborated. Afterwards, its prospect was outlooked.