刘 臻,刘冬英,来伟旗,傅 颖,陈建国,梅 松,张 岭,么春艳,王 茵.甲鱼肽粉对小鼠免疫功能影响的研究[J].食品安全质量检测学报,2013,4(3):830-834
甲鱼肽粉对小鼠免疫功能影响的研究
The effect of turtle peptide powder on immune function in mice
投稿时间:2013-05-10  修订日期:2013-06-02
DOI:
中文关键词:  甲鱼肽粉  增强免疫力  小鼠
英文关键词:turtle peptide powder  enhancement of immune function  mice
基金项目:浙江省科技计划项目(2009F20035、2009R50028、2011F20038)、浙江省卫生高层次创新人才培养项目、浙江省医学支撑学科营养学(11-zc03)
作者单位
刘 臻 浙江省医学科学院 
刘冬英 浙江省医学科学院 
来伟旗 浙江省医学科学院 
傅 颖 浙江省医学科学院 
陈建国 浙江省医学科学院 
梅 松 浙江省医学科学院 
张 岭 浙江省医学科学院 
么春艳 浙江省医学科学院 
王 茵 浙江省医学科学院 
AuthorInstitution
LIU Zhen Zhejiang Academy of Medical Sciences 
LIU Dong-Ying Zhejiang Academy of Medical Sciences 
LAI Wei-Qi Zhejiang Academy of Medical Sciences 
FU Ying Zhejiang Academy of Medical Sciences 
CHEN Jian-Guo Zhejiang Academy of Medical Sciences 
MEI Song Zhejiang Academy of Medical Sciences 
ZHANG Ling Zhejiang Academy of Medical Sciences 
YAO Chun-Yan Zhejiang Academy of Medical Sciences 
WANG Yin Zhejiang Academy of Medical Sciences 
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中文摘要:
      目的 研究甲鱼肽粉对小鼠免疫力的影响。方法 将 200 只雌性健康小鼠随机分为 5 个实验组, 每组 分为低、中、高和阴性对照组, 连续灌胃给药 30 d 后对不同剂量组进行细胞免疫功能(Con A 诱导小鼠脾淋巴 细胞转化实验、迟发型变态反应)、体液免疫功能(抗体生成细胞检测、血清溶血素的测定)、单核-巨噬细胞功 能(碳廓清实验、小鼠腹腔巨噬细胞吞噬鸡红细胞实验)和 NK 细胞活性检测。结果 甲鱼肽粉有促进小鼠迟发 型变态反应的作用, 能提高小鼠抗体生成细胞数和血清溶血素水平, 增强小鼠 NK 细胞的活性。结论 在本实 验条件下, 甲鱼肽粉对小鼠具有一定的免疫增强作用
英文摘要:
      Objective To study the effects of turtle peptide powder on immune function in mice. Methods A total of 200 female mice were divided into five groups randomly and fed with the powder at the dosage of 0, 0.25, 0.5, and 1.5 g/(kg·bw) respectively for 30 d and then 7 indexes of immune function were tested to judge the effects of the turtle peptide powder on immune system. Results In comparison with the control group, the delayed hypersensitivity was accelerated, and the quantity of the antibody-producing cell and the sheep eryt- hrocyte antibody levels in serum were raised and the activity of NK cell was improved. Conclusion Turtle peptide powder could enhance immune function of mice.
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