姓名：詹菁

性别：女

学历：博士

职称：副教授

工作单位：中国农业大学

教育情况：

2014.08-2019.06：中国农业大学，理学院，理学博士

2010.08-2014.06：中国农业大学，理学院，理学学士

工作经历：

2021.06-至今：中国农业大学，优秀人才引进，副教授

2019.07-2021.05：中国科学院生态环境研究中心，环境化学与生态毒理学国家重点实验室，博士后

所主持的项目及其进展：

1.国家自然科学基金青年基金项目“晚期糖基化终产物-羧甲基赖氨酸（AGEs-CML）对肠道屏障的损伤及机制研究”，2023-2025年，主持。

2.中国农业大学基础与前沿交叉研究专项“新型全氟化合物的肠道毒性筛查与评估”，2024.01-2024.12，主持。

3.国家重点研发计划项目课题“冷链食品储运过程化学危害阻控关键技术研发及评价”，2022-2026年，项目骨干。

4.中国博士后科学基金面上项目“红细胞介导的大气细颗粒物诱发血栓的机理研究”，2020-2021年，主持。

所受奖项：

1.第十届中国科协青年人才托举工程，2024年。

2.中国检验检测学会科学技术奖二等奖（第一完成人），2024年。

主要研究方向：

1. 食源性污染物的痕量分析

2. 环境污染物的健康效应与毒理学机制

代表性著作：

1.Qiang, X., Wang, X.Y., Liang, S.M., Li, S.G., Lv, Y.C., Zhan, J*. Long-term effects of Nε-carboxymethyllysine intake on intestinal barrier permeability: Associations with gut microbiota and bile acids. Food Research International, 2025, 201: 115543.

2.Wang, X.Y.#, Lv, Y.C.#, Qiang, X., Liang, S.M., Li, R.S., Zhan, J.*, Liu, J.Y.*. Perfluorooctanoic acid (PFOA) and its alternative perfluorobutanoic acid (PFBA) alter hepatic bile acid profiles via different pathways. Science of The Total Environment, 2024, 950, 175312.

3.Qiang, X., Liang, S.M., Lv, Y.C., Wang, X.Y., Zhang. H., Zhan, J.*. Advanced glycation end products (AGEs) impair the intestinal epithelial barrier via STAT3 activation mediated by macrophages. Food and Chemical Toxicology, 2024, 192, 114966.

4.Zhan, J., Liu, S.Q.*, Zhang, Y.Z., Sun, Z.D., Zhou, Q.F., Jiang, G.J. Silica nanoparticles trigger phosphatidylserine exposure in red blood cells and induce thrombosis risk. Environmental Pollution, 2023, 327, 121591.

5.Niu, X.K., Zhang, N.N., Li, S.S., Li, N., Wang, R., Zhang, Q., He, J.J., Sun, E., Kang, X.H. *, Zhan, J*. Bifidobacterium animalis subsp. lactis MN-Gup protects miceagainst gut microbiota-related obesity and endotoxemia induced by a high fat diet. Frontiers in Nutrition, 2022, 9, 992947.

6.Wang, C.Y., Li, S.S., Sun, E.N., Xiao, R., Wang, R., Ren Y.M., He, J.J., Zhang, Q., Zhan, J*. Effects of fermented milk containing bifidobacterium animalis subsp. lactis MN‐Gup (MN‐Gup) and MN‐Gup‐Based synbiotics on obesity induced by high fat diet in rats. Nutrients, 2022, 14, 2631.

7.Xiao, R., Wang, R., Li S.S., Kang, X.H., Ren Y.M., Sun, E.N., Wang, C.Y., He, J.J., Zhan, J*. Preliminary evaluation of potential properties of three probiotics and their combination with prebiotics on GLP-1 secretion and type 2 diabetes alleviation. Journal of Food Quality, 2022, 2022, 8586843.

8.Zhan, J., Liu, S.Q.*, Sun, Z.D., Zhou, Q.F., Hu, L.G., Qu, G.B., Zhang, J.Q., Zhao, B., Jiang, G.J. Environmental impacts on the transmission and evolution of COVID-19 combing the knowledge of pathogenic respiratory coronaviruses. Environmental Pollution, 2020, 267, 115621.

9.Zhan, J., Ma, X.R., Liu, D.H., Liang, Y.R., Li, P.Z., Cui, J.N., Zhou, Z.Q., Wang, P*. Gut microbiome alterations induced by tributyltin exposure are associated with increased body weight, impaired glucose and insulin homeostasis and endocrine disruption in mice. Environmental Pollution, 2020, 266, 115276.

10.Zhan, J., Liang, Y.R., Liu, D.H., Ma, X.R., Li, P.Z., Zhai, W.J., Zhou, Z.Q., Wang, P*. Pectin reduces environmental pollutant-induced obesity in mice through regulating gut microbiota: A case study of p,p’-DDE. Environment International, 2019, 130, 104861.

11.Liang, Y.R.1, Zhan, J.1, Liu, D.H., Luo, M., Han, J.J., Liu, X.K., Liu, C., Cheng, Z., Zhou, Z.Q., Wang, P*. Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota. Microbiome, 2019, 7, 19.

12.Zhan, J., Liang, Y.R., Liu, D.H., Ma, X.R., Li, P.Z., Liu, C., Liu, X.K., Wang, P*, Zhou, Z.Q*. Antibiotics may increase triazine herbicide exposure risk via disturbing gut microbiota. Microbiome, 2018, 6, 224.

13.Zhan, J.1, Liang, Y.R.1, Liu, D.H., Liu, C., Liu, H., Wang, P., Zhou, Z.Q*. Organochlorine pesticide acetofenate and its hydrolytic metabolite in rabbits: Enantioselective metabolism and cytotoxicity. Pesticide Biochemistry and Physiology, 2018, 145, 76-83.

14.Zhan, J., Li, J.D., Liu, D.H., Liu, C., Yang, G.G., Zhou, Z.Q., Wang, P*. A simple method for the determination of organochlorine pollutants and the enantiomers in oil seeds based on matrix solid-phase dispersion. Food Chemistry, 2016, 194, 319-324.