姓名：石文标

性别：男

学历：博士

职称：副教授

工作单位：中国农业大学

教育情况：

2013.09-2019.04：荷兰瓦赫宁根大学，营养生理学博士

2010.09-2013.06：中国农业科学院，硕士

2006.09-2010.07：西南民族大学，学士

工作经历：

2021.07-至今：中国农业大学，优秀人才引进，副教授

2019.08-2021.03：美国康奈尔大学，博士后

所主持的项目及其进展：

主持十四五国家重点研发计划专项子课题两项（课题-典型新食品原料营养功效评价用标准物质研制2022YFF0710402；课题-功能性维生素生物安全评价技术体系研究及应用2023YFF1103704），北京市自然科学基金青年项目一项（7244368）,省部级课题2项（预制菜营养素评价），横向课题3项。中国营养学会营养与免疫分会委员、中国毒理学会委员。

主要研究方向：

1. 食源性生物活性因子影响代谢健康的分子生理机制研究

2. 维生素缺乏症的生物标志物研究

3. 烟酰胺腺嘌呤二核苷酸(NAD )依赖性酶Sirtuin蛋白家族的功能研究

4. 维生素生物合成安全评价研究

代表性著作：

·Yu Chen; Siyuan Sun; Chenxu Lu; Yixuan Li; Bing Fang; Xiangfeng Tang; Xuepeng Li; Weiru Yu; Yumei Lei; Longjie Sun; Ming Zhang; Jiazeng Sun; Ping Liu; Yongting Luo; Xingwang Zhao; Jing Zhan; Libing Liu; Rong Liu; Jiaqiang Huang; Ziwei Yi; Yifei Yu; Weihan Xiao; Zheng Ding; Lei Li; Dan Su; Fazheng Ren; Changchang Cao; Ran Wang; Wenbiao Shi; Juan Chen ; The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells, Exploration, 2025, 0(270015):1-20（共同通讯）

·Jingyi Qi, Shuaishuai Zhou, Guisheng Wang, Rongrong Hua, Xiaoping Wang, Jian He, Zi Wang, Yinhua Zhu, Junjie Luo, Wenbiao Shi, Yongting Luo, Xiaoxia Chen. The Antioxidant Dendrobium officinale Polysaccharide Modulates Host Metabolism and Gut Microbiota to Alleviate High-Fat Diet-Induced Atherosclerosis in ApoE-/- Mice. Antioxidants. 2024 May 13;13(5):599.（共同通讯）

·Lu Chen, Qian Zhang, Ziwei Yi, Yu Chen, Weihan Xiao, Dan Su, Wenbiao Shi. Risk Assessment of (Herbal) Teas Containing Pyrrolizidine Alkaloids (PAs) Based on Margin of Exposure Approach and Relative Potency (REP) Factors. Foods 2022, 11(19), 2946. https://doi.org/10.3390/foods11192946. （唯一通讯）

·Ziquan Lv#, Wenbiao Shi#, Qian Zhang. Role of Essential Amino Acids in Aging-induced Bone Loss. International Journal of Molecular Sciences 2022 Sep 24;23(19):11281. doi: 10.3390/ijms231911281.（共同第一作者）

·Guohua Hou, Yuan Li, Qimeng Wang, Huijuan Zhang, Shuang Liang, Bin Liu, Wenbiao Shi. iRGD-grafted N-trimethyl chitosan-coated protein nanotubes enhanced the anticancer efficacy of curcumin and melittin. International Journal of Biological Macromolecules 222 (2022) 348–359.（共同通讯）

·Shi W, Hegeman MA, van Dartel DAM, Tang J, Suarez M, Swarts H, van der Hee B, Arola L, Keijer J. Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet. Molecular Nutrition & Food Research. 2017 Aug;61(8). doi: 10.1002/mnfr.201600878.

·Shi W, Hegeman MA, Doncheva A, Grovenstein MB, de Boer VCJ, Keijer J. High dose of dietary nicotinamide riboside (NR) induces glucose intolerance and white adipose tissue (WAT) dysfunction of mice fed a mildly obesogenic diet. Nutrients. 2019 Oct 13;11(10). pii: E2439. doi: 10.3390/nu11102439.

·Shi W, Hegeman MA, Doncheva A, van der Stelt I, Grovenstein MB, van Schothorst EM, de Boer VCJ, Keijer J. Transcriptional response of white adipose tissue to vitamin B3 withdrawal. Molecular Nutrition & Food Research. 2019 Apr 16:e1801100. doi: 10.1002/mnfr.201801100.