姓名:魏芸

性别:

学历:博士研究生

职称:教授

工作单位:北京化工大学

 

教育情况:

1993年毕业于辽宁大学化学系,获学士学位; 

1998年毕业于中国科学院兰州化学物理研究所,获理学博士学位。

 

工作经历:

1998.07-2004.12:北京市新技术应用研究所,副研究员;

2005.01-至今:北京化工大学,教授。

2009.01-2009.04:英国布鲁耐尔大学(Brunel University),访问学者,教授;

2012.08-2013.08:美国国立卫生研究院(National Institutes of Health),访问学者,教授.

 

所主持的项目及其进展

主持项目:

主持国家自然科学基金、国家重点研发计划项目、科技部重大新药创制、国家公益性行业专项;教育部新世纪优秀人才计划;北京市新星计划;北京市自然科学基金;北京市优秀人才培养专项基金;北京市新星交叉学科项目;中石化等项目。

 

所受奖项:

获奖及标准颁布情况:

1)四种制备色谱分离新技术的研究及在黄顶菊等植物样品分离中的应用,中国分析测试协会科学技术一等奖,证书号2012-1-006-01-R,2012-10,第1完成人。

2)新外来入侵植物黄顶菊防控技术与应用,农业部神农奖三等奖,证书号KJ2013-R3-027-05,2013-11-8,第5完成人。

3)防治阿尔茨海默病中药复方的物质基础与药理机制研究,北京市科学技术成果三等奖,2016年,第3完成人。

4)牵头起草国家标准《甘蔗皮渣中对香豆酸检测方法 高效液相色谱法》(GB/T 40833-2021)及国家标准《苹果及苹果制品中根皮苷的检测方法 高效液相色谱法》(GB/T  44620-2024)。

5)获批8项国家实物标准样品。

6)获国家发明专利授权16项。

  

主要研究方向:

1、磁性纳米分离富集材料及新型水凝胶材料研究;

2、植物分离分析及资源化(分离方法学研究-逆流色谱技术及液相色谱技术研究、入侵植物及中草药活性成分研究、国家标准及标准样品研制);

3、食品、环境安全分析及肿瘤标志物分析检测。

 

代表性著作:

[1] Yun Wei*, Ailin Tian, Yan Li, Xiong Wang and Bo Cao. A General Chiral Selector Immobilized on Silica Magnetic Microspheres for Direct Separation of Racemates. J. Mater. Chem. 2012, 22: 8499-8504.

[2] Yun Wei*, Yan Li, Ailin Tian, Yuntian Fan and Xiong Wang. Ionic Liquid Modified Magnetic Microspheres for Isolation of Heme Protein with High Binding Capacity. J. Mater. Chem. B, 2013, 1 (15), 2066-2071. 

[3] Lin Chang, Pengyu Bi, Yanan Liu, Yinglin Mu, Fengquan Nie, Shizhong Luo, Yun Wei*. Simultaneous Analysis of Trace Polymer Additives in Plastic Beverage Packaging by Solvent Sublation Followed by High-Performance Liquid Chromatography. J. Agric. Food Chem., 2013, 61, 7165-7171.

[4] Yali Gao, Yanxiang Gu, Yun Wei*, Determination of polymer additives-antioxidants and UV absorbers by High Performance Liquid chromatography coupled with UV photodiode array detection in food stimulants. J. Agri. Food Chem. 2011, 59: 12982-12989.

[5] Lin Chang, Pengyu Bi, Xiaochen Li, Yun Wei*. Study of solvent sublation for concentration of trace phthalate esters in plastic beverage packaging and an alysis by gas chromatography-mass spectrometry. Food Chem., 2015, 177, 127-133.

[6] Yun Wei*, Wenwen Huang, Yanxiang Gu. Online Isolation and Purification of Four Phthalide Compounds from Chuanxiong Rhizoma Using Counter-current Chromatography Coupled with Semi Preparative Liquid Chromatography. Journal of Chromatograph A. 2013, 1284, 53-58.

[7] Ailin Tian, Jing Qi, Yating Liu, Fengkang Wang, Yoichiro Ito, Yun Wei*, Chiral magnetic microspheres purified by centrifugal field flow fractionation and microspheres magnetic chiral chromatography for benzoin racemates separation. J. Chromatogr. A, 2013, 1305, 333-337.

[8] Lin Chang, Yun Wei*, Peng-yu Bi, Qian Shao. Recovery of liquiritin and glycyrrhizic acid from Glycyrrhiza uralensis Fisch by aqueous two-phase flotation and multi-stage preparative high performance liquid chromatography, Separation and Purification Technology 2014, 134, 204-209.

[9] Quan Li, Kaite Peng, Yanzhen Lu, Aoxin Li, Fenfang Che, Yuanyuan Liu, Xingjun Xi, Qiao Chu, Tao Lan and Yun Wei*, Synthesis of fluorescent ionic liquid-functionalized silicon nanoparticles with tunable amphiphilicity and selective determination of Hg2 . J. Mater. Chem. B, 2018, 6, 8214-8220.

[10] Yanzhen Lu, Yang Du, Xiaoyan Qin, Huantong Wu, Yong Cheng, Yun Wei*. Comprehensive evaluation of effective polyphenols in apple leaves and their combinatory antioxidant and neuroprotective activities. Ind. Crop. Prod., 2019, 129, 242-252.

[11] Aoxin Li, Hanwen Wu, Yuanjiao Feng, Siyu Deng, Aijiao Hou, Fenfang Che, Yuanyuan Liu, Qianqian Geng, Hanwen Ni and Yun Wei*, A strategy of rapidly screening out herbicidal chemicals from Eucalyptusessential oils. Pest Management Science, 2020, 76, 917-927.

[12] Quan Li, Zhiwei Guo, Xiaoyan Zhao, Taoyi Zhang, Jing Chen, and Yun Wei*, One-pot synthesis of 2,2'-dipicolylamine derived highly photoluminescent nitrogen-doped carbon quantum dots for Fe3  detection and fingermark detection. Nanotechnology, 2020, 31, 335501.

[13] Zhiwei Guo, Quan Li, Zhiyue Li, Cong Liu, Xuerui Liu, Yuanyuan Liu, Genlai Dong, Tao Lan, Yun Wei*. Fabrication of effificient alginate composite beads embedded with N-doped carbon dots and their application for enhanced rare earth elements adsorption from aqueous solutions. Journal of Colloid and Interface Science 2020, 562, 224-234.

[14] Cong Liu, Wenjuan Wang, Hao Li, Jiangang Liu, Peng Zhang, Yong Cheng, Xiaoyan Qin, Yang Hu and Yun Wei*. The neuroprotective effects of isoquercitrin purified from apple pomace by high-speed countercurrent chromatography in the MPTP acute mouse model of Parkinson’s disease. Food & Function, 2021, 12, 6091-6101.

[15] Quan Li, Zhile Bai, Xingjun Xi, Zhiwei Guo, Cong Liu, Xuerui Liu, Xiaoyan Zhao, Zhiyue Li, Yong Cheng, and Yun Wei*. Rapid microwave-assisted green synthesis of guanine-derived carbon dots for highly selective detection of Ag  in aqueous solution, Spectrochim. Acta. A., 2021, 248, 119208.

[16] Quan Li, Taoyi Zhang, Jing Chen, Wenxi Ji and Yun Wei*. In situ synthesis of green emitting polydopamine polymer dots based on Fenton reaction for the turn on fluorescence multi-sensing platform. J. Mater. Chem. B, 2021, 9, 5503-5513.

[17] Zhiyue Li, Zhiwei Guo, Taoyi Zhang, Quan Li, Jing Chen, Wenxi Ji, Cong Liu, Yun Wei*, Fabrication of in situ ZIF-67 grown on alginate hydrogels and its application for enhancing Cu(II) adsorption from aqueous solutions, Colloids and Surfaces B: Biointerfaces, 2021, 207, 112036.

[18] Jiajia Zeng, Wenjuan Wang, Junjun Lin, Yuchi Zhang, Hao Li, Jiangang Liu, Chen Yan, Yanxiang Gu, Yun Wei*. Purification of menthone and menthol from Mentha haplocalyx by suspension particle assisted solvent sublation, neuroprotective effect in vitro and molecular docking of menthol on amyloid-beta. J. Chromatogr. A, 2022, 1674, 463125.

[19] Qinglong Cao, Zhen Shu, Taoyi Zhang, Wenxi Ji, Jing Chen, Yun Wei*. Highly Elastic, Sensitive, Stretchable, and Skin-Inspired Conductive Sodium Alginate/Polyacrylamide/Gallium Composite Hydrogel with Toughness as a Flexible Strain Sensor. Biomacromolecules, 2022, 23(6), 2603-2613.

[20] Mengying Zhang, Yuxiang Liu, Yun Wei*, Ratiometric fluorescent probe based on dual-emissive carbon dots for determination of silver ions. Dyes and Pigments, 2024, 226, 112143.

[21] Yuwei Guan, Yanhong Lu, Yun Wei*, Fabrication of a ratiometric fluorescent probe based on Tb3 doped dual-emitting carbon dots for the detection of cytochrome C. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 316, 124310.

[22] Chen Yan, Jiajia Zeng, Hao Li, Xian Pan, Jiangang Liu, Yun Wei*. Research on the chemical composition of Mentha haplocalyx volatile oils from different geographical origins by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry in combination with principal component ana lysis and the enrichment of bioactive compounds by particle-assisted solvent sublation. Microchemical Journal, 2023, 188, 108477.

[23] Mengyao Gao, Chen Yan, Na Li, Yun Wei*. Electroosmotic coupled with particle-assisted deep eutectic solvent flotation for the enrichment of eugenol from clove. Microchemical Journal, 2024, 205, 111326.

[24] Xuan Cao, Qinglong Cao, Taoyi Zhang, Wenxi Ji, Usman Muhammad, Jing Chen, and Yun Wei*. Hydrophobically associated hydrogel for high sensitivity and resolution of interdigital electrode pressure sensor. Biomacromolecules, 2024, 25, 143−154.

[25] Wenjuan Wang, Wenting Li, Jiaqi Shi, Saeed Ahmed Memon, Yun Wei*. The enrichment and separation of lanthanides ions from wastewater using solvent sublation coupled with high- speed countercurrent chromatography. Journal of Molecular Liquids. 2024, 399, 124375.