姓名：刘连亮
性别：男
学历：工学博士
职称：副教授、硕士生导师
工作单位：宁波大学食品与药学学院
教育情况：
2012 年毕业于浙江大学食品科学专业，获工学博士学位。
2017-2019 年于 University of Kansas Medical Center 和 University of Louisville 从事博士后研究
工作经历：
至 今,宁波大学食品与药学学院副教授、硕士生导师
主要研究方向：
食品 生物技术与食品安全（谷物多酚调控美拉德反应；多酚递送体系及其益生评价；肠
道菌群免疫代谢调控）
主要课题：
1．国家自然科学基金项目《裸燕麦酚类化合物与β-葡聚糖介导肠道菌群互作及氧
化应激调控研究》2017-2019 主持，结题
2．浙江省自然科学基金《燕麦酚类化合物抑制食源性 AGEs 生成及调控 DC 细胞
炎性反应研究》2021-2023 主持，在研
3．浙江省自然科学基金《可口革囊星虫寡糖对 AGEs 诱导内皮细胞损伤的调控构
效关系及机制》2015-2017 主持，结题
4．宁波市公益计划项目《燕麦活性成分高效制备耦合技术及其 AGEs 抑制研究》
2019-2021 主持，结题
5．宁波市自然基金项目《燕麦酚类化合物抑制美拉德反应 AGEs 生成机理研究》
2019-2020 主持，结题
代表性著作：
近几年代表性论文
1. Lezhen Dong, Ying Li, Qin Chen, Yahui Liu, Zufang Wu, Daodong Pan, Ning Yan, Lianliang Liu*.
Cereal polyphenols inhibition mechanisms on advanced glycation end products and regulation on type
2 diabetes. Critical Reviews in Food Science and Nutrition. Doi: 10.1080/10408398.2023.2213768.
（SCI 一区，TOP）
2. Lezhen Dong, Ying Li, Qin Chen, Yahui Liu, Zhaohui Qiao, Shangyuan Sang, Jingshun Zhang,
Shengnan Zhan, Zufang Wu, Lianliang Liu*. Research advances of advanced glycation end products in
milk and dairy products: formation, determination, control strategy and immunometabolism via gut
microbiota. Food Chemistry, 417(2023):135861, Doi: 10.1016/j.foodchem.2023.135861. （SCI 一区，
TOP）
3. Qin Chen, Lezhen Dong, Ying Li, Yahui Liu, Qiang Xia, Shangyuan Sang, Zufang Wu, Jianbo Xiao*,
Lingyi Liu*, Lianliang Liu*. Research advance of non-thermal processing technologies on ovalbumin
properties: the gelation, foaming, emulsification, allergenicity, immunoregulation and its delivery system
application. Critical Reviews in Food Science and Nutrition. Doi: 10.1080/10408398.2023.2179969.
（SCI 一区，TOP）
4. Zhang Yunzhen, Li Yueqin, Ren Xiaxia, Zhang Xin, Wu Zufang, Liu Lianliang*. The positive
correlation of antioxidant activity and prebiotic effect about oat phenolic compounds. Food Chemistry,
402(2023): 134231. （SCI 一区，TOP）
5. Ying Li, Chuan Qin, Lezhen Dong, Xin Zhang, Zufang Wu, Lingyi Liu, Junsi Yang, Lianliang Liu*.
Whole grain benefit: oat β-glucan and phenolic compounds synergistically regulates hyperlipidemia via
gut microbiota in high-fat-diet mice. Food & Function, 2022, 13(24), 12686-12696. （SCI 一区，TOP）
6. Dong Lezhen, Qin Chuan, Li Ying, Wu Zufang, Liu Lianliang*. Oat phenolic compounds regulate
metabolic syndrome in high fat diet-fed mice via gut microbiota. Food Bioscience. 50(2022): 101946.
（SCI 一区，TOP）
7. Liu Yahui, Weng Peifang, Liu Yanan, Wu Zufang, Wang Lei*, Liu Lianliang*. Citrus pectin research
advances: Derived as a biomaterial in the construction and applications of micro/nano-delivery systems.
Food Hydrocolloids,133(2022): 107910. （SCI 一区，TOP）
8. Li Ying, Dong Lezhen, Mu Zhishen*, Liu Lingyi, Yang Junsi, Wu Zufang, Pan Daodong, Liu Lianliang*. Research Advances of Lactoferrin in Electrostatic Spinning, Nano Self-Assembly, and Immune and Gut
Microbiota Regulation. Journal of Agricultural and Food Chemistry. 70(33):10075-10089. （SCI 一
区，TOP）
9. Yueqin Li, Yao Peng, Yingbin Shen, Yunzhen Zhang, Lianliang Liu*, Xinquan Yang*. Dietary
polyphenols: regulate the advanced glycation end products (AGEs)-RAGE axis and the microbiota-gut
brain axis to prevent neurodegenerative diseases. Critical Reviews in Food Science and Nutrition. Doi:
10.1080/10408398.2022.2076064. （SCI 一区，TOP）
10. Jingshun Zhang, Qin Chen, Yunzhen Zhang, Yiping Ren*, Lianliang Liu*. Characterization and
determination of bovine immunoglobulin G in milk and dairy products by ultra-high performance liquid
chromatography mass spectrometry. Food Chemistry, 390(2022):133170. （SCI 一区，TOP）
11. Zhang Yunzhen, Dong lezhen, Liu Lingyi, Wu Zufang, Pan Daodong, Liu Lianliang*. Recent advances
of stimuli-responsive polysaccharide hydrogels in delivery systems: A review. Journal of Agricultural
and Food Chemistry. 70(21):6300-6316. （SCI 一区，TOP）
12. Qin Chen, Ying Li, Lezhen Dong, Raran Shi, Zufang Wu, Lianliang Liu*, Jingshun Zhang*, Zufang
Wu，Daodong Pan *. Quantitative determination of Nepsilon-(carboxymethyl)lysine in sterilized milk
by isotope dilution UPLC-MS/MS method without derivatization and ion pair reagents. Food chemistry.
385(2022): 132697. （SCI 一区，TOP）
13. Zhang Yunzhen, Li Yueqin, Xia Qiang, Liu Lianliang*, Wu zufang, & Pan daodong. Recent advances
of cereal beta-glucan on immunity with gut microbiota regulation functions and its intelligent gelling
application. Critical Reviews in Food Science and Nutrition. doi: 10.1080/10408398.2021.1995842.
（SCI 一区，TOP）
14. Chuan Qin, Yueqin Li,Yunzhen Zhang, Lianliang Liu*, Zufang Wu, Peifang Weng. Insights into oat
polyphenols against advanced glycation end products mechanism by spectroscopy and molecular
interaction. Food Bioscience. 43(2021), 101313.
15. Lianliang Liu, Rong Jin, Jiaqing Hao, Jun Zeng, Di Yin, Yanmei Yi, Mingming Zhu, Anita Mandal,
Yuan Hua, Chin K. Ng, Nejat K. Egilmez, Edward R. Sauter, Bing Li*. Consumption of the fish oil high
fat diet uncouples obesity and mammary tumor growth through induction of reactive oxygen species in
pro-tumor macrophages. Cancer Research, 2020, 80(12): 2564-2574. （SCI 一区，TOP）
16. Zhihao Yang, Chuan Qin, Peifang Weng, Xin Zhang, Qiang Xia, Zufang Wu, Lianliang Liu*, Jianbo
Xiao*. In vitro evaluation of digestive enzyme inhibition and antioxidant effects of naked oat phenolic
acid compound (OPC). International Journal of Food Science and Technology, 2020, 55(6): 2531-2540.
参编教材
《Dietary Supplements with Antioxidant Activity: Understanding Mechanisms and Potential Health
Benefits》, edited by Cesarettin Alasalvar, Fereidoon Shahidi and Chi-Tang Ho.
《Handbook of Dietary Flavonoids》, edited by Jianbo Xiao.
《天然产物提取工艺学》
