姓名:李武

性别:

学历:博士

职称:教授

工作单位:五邑大学

 

教育情况:

2006.09-2010.03 江南大学食品学院食品营养与安全专业博士

1995.09-1999.07 内蒙古大学生命科学学院微生物学专业学士

 

工作经历:

2021年6月至今,五邑大学 生物科技与大健康学院 教授

2012.6-2021.5,海南大学食品科学与工程学院 教授/系主任/副院长 博士生导师

/教育部热带多糖资源利用工程研究中心副主任

/海南省食品营养与功能食品重点实验室副主任

2016.11-2017.5,澳大利亚CRSIO Food and Nutrition访问学者

2010.6-2012.6,广东省农业科学院蚕业与农产品加工研究所助理研究员

1999.7-2006.9,内蒙古双奇药业股份有限公司质量部、研发部助理工程师

 

所主持的项目及其进展

1.  国家自然科学基金项目:龙眼多糖肠道菌群代谢物基于DC途径调节肠道免疫的作用与机制(31960481), 41万,202001- 202312,主持;

2.  国家自然科学基金项目:基于Toll样受体通路的干制龙眼多糖免疫调节活性增效机制研究(31360380),40万,201401-201712,主持;

3.  广东省重点建设学科科研能力提升项目:戈登氏菌U82 转化鞣花酸改善非酒精性脂肪肝的作用与机制(2022ZDJS026),50万,202301-202512,主持

4. 海南省自然科学基金-高层次人才项目:鞣花酸生物转化尿石素的特征性肠道菌群与代谢机制研究(320RC511),7万,202012-202312,主持;

5.  海口市重点科技计划项目:润肠通便食用调和油脂的研发及市场推广(2020-022),80万,202008-202208,主持;

6.  企业委托横向项目:润肠通便食用调和油脂研发(HD-KYH-2019043),18万元,201909-202109,主持;

7.  企业委托横向项目:灰树花粗多糖的分离纯化与免疫功能评价(HD-KYH-2020087),15万元,202010-202110,主持.

 

主要研究方向:

食品营养、农产品加工等领域:

1.营养与动脉粥样硬化等慢性代谢性疾病;

2.肠道菌群与健康;

3.天然活性产物;

4.农产品加工。

 

代表性著作:

1. Wenyan Xian, Shiying Yang, Yu Deng, Yuzhe Yang, Chunlian Chen, Wu Li* (通讯作者), Ruili Yang*. Distribution of Urolithins Metabotypes in Healthy Chinese Youth: Difference in Gut Microbiota and Predicted Metabolic Pathways. Journal of Agricultural and Food Chemistry, 2021, 69:13055−13065(封面文章,中科院大类1区,TOP期刊,IF=5.270)

2. Huang XX, Li W*(通讯作者),You BY, Tang W, Gan TS, Feng C,Li CF, Yang, RL*. Serum Metabonomic Study on the Antidepressant-like Effects of Ellagic Acid in a Chronic Unpredictable Mild Stress-Induced Mouse Model. Journal of Agricultural and Food Chemistry, 2020, 68:9546-9556.(封面文章,中科院大类1区,TOP期刊,IF=5.270)

3.  Wu Li, Ruili Yang*, Danyang Ying, Jiawen Yu, Luz Sanguansri, Mary Ann Augustin. Analysis of polyphenols in apple pomace: A comparative study of different extraction and hydrolysis procedures, Industrial Crops and Products, 2020, 147, 112250.(中科院大类1 区,ESI高被引,TOP期刊,IF=5.644)

4.  Wang S, Chen J, Feng C, Lan H, Xu J, Yang R, Li C, Li W*(通讯作者). Effects of simulated digestion on the structural characteristics and dendritic cell activation of longan polysaccharides. International Journal of Biological Macromolecules. 2023,238:124114. (中科院大类1区,TOP期刊,IF=8.025)

5.  Wu Li, Junhong Huang, Lin Zheng, Wanshun Liu, Liqi Fan, Baoguo Sun, Guowan Su, Jucai Xu*, Mouming Zhao*, A fast stop-flow two-dimensional liquid chromatography tandem mass spectrometry and its application in food-derived protein hydrolysates. Food Chemistry, 2022,11:135000(中科院大类1区,TOP期刊,IF=9.231)

6.  Cai, K; Dou, R ; Lin, X (Lin, Xue) ; Hu, XP; Wang, ZL; Liu, SX; Li, CF ; Li, W* (通讯作者). Changes in Phenolic Profiles and Inhibition Potential of Macrophage Foam Cell Formation during Noni (Morinda citrifolia Linn.) Fruit Juice Fermentation. Fermentation-Basel, 2022,8(5):e201(中科院大类2区,IF=5.123)

7.  Haibo Lan, Wu Li*(通讯作者), Jucai Xu, Yuzhe Yang, Zhaolun Tan, Ruili Yang. A Novel Polysaccharide Isolated from Fresh Longan (Dimocarpus longan Lour.) Activates Macrophage via TLR2/4-mediated PI3/AKT and MyD88/TRAF6 Pathways. Frontiers in Pharmacology, 2021, 786127(中科院大类2区,TOP期刊,IF=5.810)

8.  You, B.Y., Yang, S.Y., Yu, J.W., Xian, W.Y., Deng, Y., Huang, W., Li, W.*(通讯作者), Yang, R.L.*. Effect of thermal and dry salt-curing processing on free and bound phenolics and antioxidant activity in Prunus mume fruits together with the phenolic bioaccessibility. LWT-Food Science and Technology. 2021, 145:111355. (中科院大类1区,TOP期刊,IF=4.953)

9.  Rong Yu, Yang Ruili, Yang Yuzhe, Wen Yazhou, Liu Sixin; Li Congfa; Hu Zhouyan, Cheng Xiangrong, Li Wu*(通讯作者). Structural characterization of an active polysaccharide of longan and evaluation of immunological activity. Carbohydrate Polymers, 2019, 213(6): 247-256. (中科院大类1区,TOP期刊,IF=7.182)

10.  Jiachao Zhang, Guangmei Yang, Yazhou Wen1, Sixin Liu, Congfa Li, Ruili Yang, Wu Li*(通讯作者). Intestinal microbiota are involved in the immunomodulatory activities of longan polysaccharide. Molecular Nutrition & Food Research, 2017,61(11):1700466 (中科院大类1区,TOP期刊,IF=5.151)