姓名:徐振上

性别:

学历:博士研究生

职称:副教授

工作单位:齐鲁工业大学生物工程学部

 

教育情况:

博士学位(2014/09 - 2018/06   山东大学  微生物技术国家重点实验室

硕士学位(2011/09 - 2014/06) 齐鲁工业大学  山东省微生物工程重点实验室

学士学位(2007/09 - 2011/06   河北大学  生命科学学院  生物技术

 

工作经历:

2018.07-至今  齐鲁工业大学生物工程学部

 

所受奖项:

山东省科学技术进步二等奖(7/7

 

主要研究方向:

乳酸菌及其活性代谢产物研究:挖掘乳酸菌的功能性代谢产物,揭示功能化合物的合成机理并实现经济高效的合成。

乳酸菌生理遗传及应用:围绕乳酸菌的生理遗传特性开展研究,以此为基础开发乳酸菌细胞工厂。

 

代表性著作:

Zhe Wang; Chunhai Li; Xi He; Kang Xu; Zhipeng Xue; Ting Wang; Zhenshang Xu*; Xinli Liu. Platycodon grandiflorum root fermentation broth reduces inflammation in a mouse IBD model through the AMPK/NF-κB/NLRP3 pathway. Food & Function. 2022

Jiapeng Wang; Xuekui Xia; Peipei Zhao; Xi He; Susu Zhang; Ting Wang; Zhenshang Xu*.

High-level secretory production of lysostaphin in Escherichia coli mutant by codon optimization and atmospheric and room temperature plasma mutagenesis. LWT. 2022

Zhenshang Xu; Yan Liang; Jian Kong; Susu Zhang; Xinli Liu; Ting Wang. A food-grade vector for Streptococcus thermophilus based on the α-complementation of β-galactosidase. Journal of Dairy Science. 2022

Jiapeng Wang; Susu Zhang; Chunhai Li; Xinli Liu; Zhenshang Xu*; Ting Wang. Efficient secretion of xylanase in Escherichia coli for production of prebiotic xylooligosaccharides. LWT. 2022

Zhenshang Xu, Can Li, Yanxin Ye, Ting Wang, Susu Zhang, Xinli Liu. The β-galactosidase LacLM plays the major role in lactose utilization of Lactiplantibacillus plantarum.  LWT. 2021

Ting Wang, Zhe Wang, Zhipeng Yang, Xin Cui, Yan Liang, Zhenshang Xu*, Xinli Liu. Effect of the fermentation broth of the mixture of Pueraria lobata, Lonicera japonica, Crataegus pinnatifida by Lactobacillus rhamnosus 217-1 on liver health and intestinal flora in mice with alcoholic liver disease induced by liquor. Frontiers in Microbiology. 2021, 12: 722171.

Zhenshang Xu, Rongling Zhang, Ting Wang, and Jian Kong. The N-terminus of Lactobacillus amylovorus feruloyl esterase plays an important role in its secretion by Lactobacillus plantarum and Escherichia coli. Microbial Cell Factories. 2021,20: 152 .

Zhenshang Xu, Zhe Wang, X in Cui, Yan Liang, Ting Wang and Jian Kong. Peptide transporter-related protein 2 plays an important role in glutathione transport of Streptococcus theromophilus. Journal of Dairy Science. 2021, 104: 3990-4001. 

Zhenshang Xu, Jian Kong, Susu Zhang, Ting Wang and Xinli Liu. Comparison of enzyme secretion and ferulic acid production by Escherichia coli expressing different Lactobacillus feruloyl esterases. Frontiers in Microbiology. 2020, 11:569716.

Zhenshang Xu, Ting Wang and Susu Zhang. Extracellular secretion of feruloyl esterase derived from Lactobacillus crispatus in Escherichia coli and its application for ferulic acid production. Bioresource Technology. 2019.

Zhenshang Xu, Xinjun Zhao, Ting Wang. The family 36 carbohydrate binding module enhances the efficiency of feruloyl esterase to release ferulic acid from destarched wheat bran. Basci & Clinical Pharmacology & Toxicology. 2019.

Ting Wang, Dong Yang, Zhenshang Xu*. Effects of fermented seaweed on the proliferation and wound healing of skin fibroblasts. Basci & Clinical Pharmacology & Toxicology. 2019. Zhenshang Xu, Huiying He, Susu Zhang, Tingting Guo and Jian Kong. Characterization of feruloyl esterases produced by the four lactobacillus species: L. amylovorus, L. acidophilus, L. farciminis and L. fermentum, isolated from ensiled corn stover. Frontiers in Microbiology. 2017, 8:941.

Zhenshang Xu, Huiying He, Susu Zhang and Jian Kong. Effects of inoculants Lactobacillus brevis and Lactobacillus parafarraginis on the fermentation characteristics and microbial communities of corn stover silage. Scientific Reports. 2017, 7(1):13614.

Zhenshang Xu, Susu Zhang, Yingli Mu and Jian Kong. Paenibacillus panacisoli enhances growth of Lactobacillus spp. by producing xylooligosaccharides in corn stover ensilages. Carbohydrate polymers. 2018, 184:435-444.

Zhenshang Xu, Susu Zhang, Rongling Zhang, Shixu Li and Jian Kong. The changes of dominant lactic acid bacteria and their metabolites during corn stover ensiling. Journal of Applied Microbiology.

Ting Wang1, Zhenshang Xu1, Shiyi Lu, Min Xin and Jian Kong. Effects of glutathione on acid stress resistance and symbiosis between Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus. International Dairy Journal. 2016, 61:22-28.

Susu Zhang1, Zhenshang Xu1,Ting Wang, and Jian Kong. Endoglucanase improve the growth of homofermentative Lactobacillus spp. in ensilages. Journal of Biotechnology. 2019.