姓名:满淑丽

性别:

学历:博士

职称:副教授

工作单位:天津科技大学

 

教育情况:

2006.9-2011.6  天津大学  应用化学    博士(硕博连读)

2002.9-2006.6  吉林大学            学士

 

工作经历:

2014.12-至今   天津科技大学 生物工程学院 副教授

2011.8-2014.11  天津科技大学 生物工程学院 讲师

 

所主持的项目及其进展:

[1] 国家自然科学基金项目“重楼皂苷作用于STAT3信号通路的抗肝癌机制研究”(编号: 82074069),项目负责人,2021.1-2024.12. (在研)

[2] 国家自然科学基金项目“基于肿瘤微环境干预的重楼皂苷抗转移性肺癌作用机制及物质基础研究”(编号:81673647),项目负责人,2017.1-2020.12. (已结题)

[3] 国家自然科学基金项目“基于代谢调控网络干预的重楼总皂苷组分配伍机制研究”(编号:81202952),项目负责人,2013.1-2015.12. (已结题)

[4] 天津市自然科学基金项目“基于细胞周期阻滞的楼黄配伍作用机制研究”(编号:13JCQNJC13400),项目负责人,2013.4-2016.3. (已结题)

[5] 食品营养与安全国家重点实验室开放课题“荔枝核辅助降糖营养因子的发掘与机制研究”(编号: SKLFNS-KF-201828),项目负责人,2018.11-2019.11.(已结题)

 

主要研究方向:

食品营养机理与功能评价、医药健康领域方向

 

代表性著作:

1.  Ma L*, Peng L, Yin LJ, Liu GZ, Man SL*. CRISPR-Cas12a powered dual mode biosensor for ultrasensitive and cross-validating detection of pathogenic bacteria. ACS Sensors.

2.  Lv PP, Man SL*, Xie L, Ma L, Gao WY*. Pathogenesis and therapeutic strategy in platinum resistance lung cancer. BBA - Reviews on Cancer. 2021, 1876, 188577.

3.  Man SL*, Liu TH, Yao Y, Lu YY, Ma L, Lu FP*. Friend or foe? The roles of inulin-type fructans. Carbohydrate Polymers. 2021, 252: 117155.

4.  Man SL1, Lu YY1, Yin LJ, Cheng XK, Ma L*. Potential and promising anti-cancer drugs from adenosine and its analogues. Drug Discovery Today. 2021, 26(6): 1490-1500.

5.  Yao Y, Liu TH, Yin LJ, Man SL*, Ye SY*, Ma L*. Polyphenol-Riched Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats. J Agr Food Chem. 2021, 69:2138-48.

6.  Wang Y1, Liu YX1, Zhang YQ1, Huo ZP, Wang GB, He Y, Man SL*, Gao WY*. Effects of the polysaccharides extracted from Chinese yam (Dioscorea opposita Thunb.) on cancer-related fatigue in mice. Food & Function. 2021, 21:10602.

7.  Man SL1, Yao JW1, Lv PP, Liu Y, Ma L*. Curcumin enhanced antitumor effects of sorafenib via regulating metabolism and tumor microenvironment. Food & Function. 2020, 11, 6422-6432.

8.  Meng X1, Dong HH1, Pan YW, Ma L, Liu CX, Man SL*, Gao WY*. Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells. Journal of Agricultural and Food Chemistry. 2019; 67(41): 11428-11435.

9.  Man SL, Ma J, Yao JW, Cui JX, Wang CX, Li Y, Ma L*, Lu FP*. Systemic Perturbations of Key Metabolites in Type 2 Diabetic Rats Treated by Polyphenol Extracts from Litchi chinensis Seeds. J Agric Food Chem. 2017; 65(35):7698-704.

10. Qiu PY, Sun JC, Man SL*, Yang H, Ma L, Yu P, Gao WY*. Curcumin attenuates N- nitrosodiethylamine-induced liver injury in mice by utilizing the method of metabonomics. Journal of Agricultural and Food Chemistry. 2017; 65 (9), 2000-7.