姓名：邓禹
性别：男
学历：博士
职称：教授
工作单位：江南大学 生物工程学院
教育情况：
2007.8-2011.5： 美国弗吉尼亚联邦大学(Virginia Commonwealth University)，化学与生命科学工程专业(Chemical and Life Science Engineering)，工学博士；导师：Dr. Stephen S. Fong, 教授；
2005.9-2007.6： 江南大学，生物工程学院, 发酵工程专业， 工学硕士；导师：陈坚，教授；
2001.9-2005.6：江南大学，生物工程专业，工学学士
工作经历：
2015.1-现在：江南大学粮食发酵工艺与技术国家工程实验室，江苏特聘教授，江苏省双创人才，博士生导师, 代谢工程团队负责人；
2013.8-2014.12: 助理教授（Assistant Professor）, 生物与农业工程系(Department of Biological and Agricultural Engineering), 美国堪萨斯州立大学(Kansas State University)；
2011.5- 2013.6：博士后研究员(Postdoctoral Research Associate)，Thayer工学院(Thayer School of Engineering)，美国达特茅斯学院(Dartmouth College)
所受奖项
1. 江苏特聘教授，2015
2. 江苏省“双创人才”，2016
3. 江苏双创团队，2017
4. 江苏省“六大人才高峰”，2016
5. 无锡市社会事业领军人才，2015
6. 江南大学至善青年学者，2016, 2017
7. 粮油学会玉米深加工分会理事，2018
主要研究方向：
发酵工程
代谢工程
合成生物学
工业微生物等
代表性著作：
1. Shenghu Zhou, Tingting Hao, Shumin Xu, Yu Deng*. Coenzyme A thioester-mediated carbon chain elongation as a paintbrush to draw colorful chemical compounds. Biotechnology Advances. 2020 Jun 5;107575. doi: 10.1016/j.biotechadv.2020.107575. Online ahead of print. (IF=10.744).
2. Mei Zhao, Dixuan Huang, Xiaojuan Zhang, Mattheos A.G. Koffas, Jingwen Zhou, Yu Deng*. Metabolic engineering of Escherichia coli for producing adipic acid through the reverse adipate-degradation pathway. Metabolic Engineering, 2018, 47:254-262. (IF = 7.263).
3. Yu Deng*, Ning Ma, Kangjia Zhu, Xuetuan Wei*, Yunying Zhao. Balancing the carbon flux distributions between the TCA cycle and glyoxylate shunt to produce glycolate at high yield and titer in Escherichia coli. Metabolic Engineering, 2018, 46: 28-34. (IF = 7.263).
4. Liying Ruan, Lu Li, Dian Zou, Cong Jiang, Zhiyou Wen, Shouwen Chen, Yu Deng*, Xuetuan Wei*. Metabolic engineering of Bacillus amyloliquefaciens for enhanced production of S-adenosylmethionine by coupling of an engineered S-adenosylmethionine pathway and the tricarboxylic acid cycle. Biotechnology for Biofuels. 2019, 12:211. (IF=5.452).
5. Mei Zhao, Guohui Li, Yu Deng*. Engineering Escherichia coli for glutarate production as the C5 platform backbone. Applied and Environmental Microbiology, 2018, 84:e00814-18. (IF= 4.016).
6. Na Chen, Jingya Wang, Yunying Zhao and Yu Deng*. Metabolic engineering of Saccharomyces cerevisiae for efficient production of glucaric acid at high titer. Microbial Cell factories, 2018, 17:67. (IF = 4.187)
7. Xi Zhang, Yunying Zhao, Yingli Liu, Jing Wang, Yu Deng*. Recent progress on bio-based production of dicarboxylic acids in yeast. Applied Microbiology and Biotechnology. 2020, 104(10):4259-4272. (IF=3.53)
8. Yu Zhou, Mei Zhao, Shenghu Zhou, Yunying Zhao, Guohui Li, Yu Deng*. Biosynthesis of adipic acid by a highly efficient induction-free system in Escherichia Coli. Journal of Biotechnology. 2020, 314-315:8-13. (IF=3.503)
9. Yunying Zhao, Chunlei Cao, Yingli Liu, Jing Wang, Shiyun Li, Jie Li, Yu Deng*. Genetic analysis of oxidative and endoplasmic reticulum stress responses induced by cobalt toxicity in budding yeast. Biochimica et Biophysica Acta-General Subjects. 2020, 1864(3):129516. (IF=3.422).
10. Guohui Li, Dixuan Huang, Xue Sui, Shiyun Li, Bing Huang, Xiao-Juan Zhang, Hui Wu, Yu Deng*. Advances in biological production of medium-chain dicarboxylic acids for nylon materials. Reaction Chemistry & Engineering. 2019. Accepted. DOI: 10.1039/C9RE00338J. (IF=3.441).
11. Yuqing Tian, Yu Deng*, Wenli Zhang*, Wanmeng Mu. Sucrose isomers as alternative sweeteners: properties, production, and applications. Applied Microbiology and Biotechnology. 2019, 103(21-22):8677-8687. (IF=3.53).
12. Hao Wu, Jiawei Huang, Yu Deng*, Wenli Zhang*, Wanmeng Mu. Production of L-ribose from L-arabinose by co-expression of L-arabinose isomerase and D-lyxose isomerase in Escherichia coli. Enzyme and Microbial Technology. 2020, 132:109443. (IF= 3.448)
13. Kangjia Zhu, Guohui Li, Ren Wei, Yin Mao, Yunying Zhao, Aiyong He, Zhonghu Bai, Yu Deng*. Systematic analysis of the effects of different nitrogen source and ICDH knockout on glycolate synthesis in Escherichia coli. Journal of Biological Engineering, 2019, 13 (1), 30 (IF= 3.429)
14. Ju Yang, Yiting Lu, Yunying Zhao, Zhonghu Bai, Zheng Ma, Yu Deng*. Site-directed mutation to improve the enzymatic activity of 5-carboxy-2-pentenoyl-CoA reductase for enhancing adipic acid biosynthesis. Enzyme and Microbial Technology, 2019, 125, 6-12 (IF= 3.448)
15. Yu Deng*, Xi Zhang, Xiaojuan Zhang. Recent advances in genetic modification systems for Actinobacteria. Applied Microbiology and Biotechnology, 2017, 101(6):2217-2226. (IF= 3.53).
16. Yu Deng*, Jia Lin, Yin Mao, Xiaojuan Zhang. Systematic analysis of an evolved Thermobifida fusca muC producing malic acid on organic and inorganic nitrogen sources. Scientific Reports, 2016, 6: 30025. (IF= 3.998).
17. Yu Deng, Mingxue Sun , Sha Xu, Jingwen Zhou. Enhanced (S)-linalool production by fusion expression of farnesyl diphosphate synthase and linalool synthase in Saccharomyces cerevisiae. Journal of Applied Microbiology, 2016, 121, 187-195. (IF=3.066).
18. Yu Deng*, Yin Mao, Xiaojuan Zhang. Driving carbon flux through exogenous butyryl-CoA: Acetate CoA-transferase to produce butyric acid at high titer in Thermobifida fusca. Journal of Biotechnology, 2015, 216:151–157. (IF= 3.503)
19. Yu Deng*, Li Zhou Ma, Yin Mao. Biological production of adipic acid from renewable substrates: current and future methods. Biochemical Engineering Journal, 2016, 105:16–26. (IF=3.475)
20. Yu Deng*, Yin Mao, Xiaojuan Zhang. Metabolic Engineering of E. coli for Efficient Production of Glycolic Acid from Glucose. Biochemical Engineering Journal, 2015, 103: 256-262. (IF=3.475)
