姓名：李敬光
性别：男
学历：博士研究生
职称：研究员
工作单位：国家食品安全风险评估中心
教育情况：
1994-1998 北京医科大学药学院 药物化学 理学学士
2000-2005 中国疾病预防控制中心 营养与食品卫生学 理学博士
工作经历：
1998-2004 中国疾病预防控制中心（中国预防医学科学院）, 营养与食品安全所, 研究实习员
2004-2007 中国疾病预防控制中心, 营养与食品安全所, 助理研究员
2007-2011 中国疾病预防控制中心, 营养与食品安全所, 副研究员
2011-2012 中国疾病预防控制中心, 营养与食品安全所, 研究员
2012至今 国家食品安全风险评估中心, 研究员
所主持的项目及其进展:
1 中国医学科学院，中国医学科学院医学与健康科技创新工程项目，2019-12M-5-024 ，食品安全监测评估关键技术，2019-01至2023-12，500万元，在研，主持。
2 科技部，国家重点研发计划项目食品安全关键技术专项，2017YFC1600500，食品污 染物暴露组解析和总膳食研究，2018-01至2021-12，2679万元，在研，主持。
3 国家自然科学基金委员会，面上项目，21477030，二噁英类物质暴露与妊娠期糖尿病 关系及相关microRNA差异表达研究，2015-01至2018-12，90万元，已结题，主持。
4 国家卫生健康委员会，食品安全国家标准制订、修订项目，spaq-2017-079，食品中 二噁英及其类似物毒性当量的测定，2019年-01至2019年-12，180万元，在研，主持
5 国家自然科学基金委员会，面上项目，21077098，全氟有机化合物新型暴露标志物和婴儿暴露途径研究，2011-01-2013-12， 36万元，已结题，主持。
6 科技部，国家国际合作专项项目，2011DFA317，食品污染监测与风险评估技术合作 研究，2012-01至2015-12，475万元，已结题，主持。
7 科技部，国家高技术研究发展计划（863计划），2006AA06Z403， 持久性有机污染 物与溴系阻燃剂监测与履约效果评估方法，2007-01至2009-12，128 万元，已结题，主持。
8 国家自然科学基金委员会，青年基金项目，20607021，生物基质中典型氟化有机污 染物的代谢表征与暴露途径研究，2007-01至2009-12，25.5万元，已结题，主持。
所受奖项：
（1）李敬光(5/10); 动物性食品中药物残留及化学污染物检测关键技术及试剂盒产业 化, 中华人民共和国国务院, 科技进步, 国家二等奖, 2007(沈建忠; 吴永宁; 何方洋; 丁双阳; 李敬光; 江海洋; 苗虹; 肖希龙; 张素霞; 万宇平).
(2) 李敬光(2/10); 食品化学污染物限量标准与检测技术, 北京市人民政府, 科技进 步, 省部二等奖, 2012(吴永宁; 李敬光; 赵云峰; 史建波; 阴永光; 苗 虹; 尚晓虹; 周萍萍; 李筱薇; 张 磊).
(3) 李敬光(2/10); 二噁英、多氯联苯和氯丙醇的痕量和超痕量检测技术的研究, 中 华医学会, 中华医学科技奖二等奖, 其他, 2005(吴永宁; 李敬光; 郑明辉; 吴文忠; 付武胜; 张建清; 赵云峰; 陈左生; 庄志雄; 邵 兵).
(4) 李敬光(2/10); 化学污染物分析技术与暴露评估及其食品安全控制标准, 中华医 学会, 中华医学科技奖二等奖, 其他, 2012(吴永宁; 李敬光; 周群芳; 任一平; 章 宇; 闻 胜; 刘稷燕; 赵云峰; 李筱薇; 苗 虹).
(5) 李敬光(3/12); 食品中热点污染物监测控制标准与配套检验方法, 中国分析测试 协会, 中国分析测试协会科学技术奖特等奖, 其他, 2014(吴永宁; 江桂斌; 李敬光; 何滨; 史建波; 邵兵; 沈海涛; 赵云峰; 苗虹; 尚晓虹; 张磊; 李筱薇).
(6) 李敬光(3/10); 食品中化学污染物与真菌毒素监控技术与标准, 中国食品科学技 术学会, 中国食品科学技术学会科技创新奖-技术进步奖一等奖, 其他, 2014(吴永宁; 江桂斌; 李敬光; 任一平; 何滨; 赵云峰; 李凤琴; 史建波; 李筱薇; 尚晓虹).
主要研究方向：
食品安全与环境健康。食品中化学污染物检测技术，污染物膳食暴露评估和风险评估，持久性有机污染物健康效应。
代表性著作：
1. Xin Liu, Lei Zhang, Liangkai Chen, Jingguang Li*, Jun Wang, Yunfeng Zhao, Liegang Liu, Yongning Wu，Identification and prioritization of the potent components for combined exposure of multiple persistent organic pollutants associated with gestational diabetes mellitus，Journal of Hazardous Materials，2021, 409: 124905
2. Xuezhen Zhao, Tian Chen , Bin Yang , Dejun Wang, Wen Sun, Yuwei Wang, Xiaodi Yang, Sheng Wen , Jingguang Li*, Zhixiong Shi*，Serum levels of novel brominated flame retardants (NBFRs) in residents of a major BFR-producing region: Occurrence, impact factors and the relationship to thyroid and liver function，Ecotoxicology and Environmental Safety，2021，208：111467
3. Lirong Gao*; Jingguang Li*; Short- and Medium-Chain Chlorinated Paraffins in Foods from the Sixth Chinese Total Diet Study: Occurrences and Estimates of Dietary Intakes in South China, Journal of Agricultural and Food Chemistry, 2020, 68：9043-9051.
4. Chen Dawei, Liu Zhibin, Barrett Holly, Han Jiajun*, Lv Bing, Li Yan, Li Jingguang*, Zhao Yunfeng, Wu Yongning, Nationwide Biomonitoring of Neonicotinoid Insecticides in Breast Milk and Health Risk Assessment to Nursing Infants in the Chinese Population. Journal of Agricultural and Food Chemistry, 2020, 68: 13906−13915
5. Fang Li, Binbin Xiang, Yan Jin, Chao Li, Songlei Ren, Yongning Wu, Jingguang Li*,
6. Qian Luo*, Hepatotoxic effects of inhalation exposure to polycyclic aromatic hydrocarbons on lipid metabolism of C57BL/6 mice. Environment International, 2020,134:105000.
7. Chen Dawei, Zhang Yiping, Lv Bing, Liu Zhibin, Han Jiajun, Li Jingguang*, Zhao Yunfeng, Wu Yongning, Dietary exposure to neonicotinoid insecticides and health risks in the Chinese general population through two consecutive total diet studies. Environment International, 2020, 135,105399
8. Yan Bao, Lei Zhang, Xin Liu, Lei Shi, Jingguang Li*, Guimin Meng, Yunfeng Zhao, Yongning Wu, Dioxin-like compounds in paired maternal serum and breast milk under long sampling intervals, Ecotoxicology and Environmental Safety, 2020, 194: 110339
9. Liu Xin, Zhang Lei, Li Jingguang*, Wang, Jun, Meng Guimin, Chi Min, Zhao Yunfeng; Wu Yongning, Relative Effect Potency Estimates for Dioxin-Like Compounds in Pregnant Women with Gestational Diabetes Mellitus and Blood Glucose Outcomes Based on a Nested Case-control Study, Environmental Science & Technology, 2019, 53：7792-7802
10. Liu Xin, Zhang Lei, Chen Liangkai, Li Jingguang*, Wang Yuxin, Wang Jun, Meng Guimin, Chi Min, Zhao Yunfeng, Chen Hongbing, Wu, Yongning, Structure-based investigation on the association between perfluoroalkyl acids exposure and both gestational diabetes mellitus and glucose homeostasis in pregnant women, Environment International, 2019, 127：85-93.
11. Fang Li, Binbin Xiang, Yan Jin, Chao Li, Jingguang Li*, Songlei Ren, Huiting Huang , Qian Luo*, Dysregulation of lipid metabolism induced by airway exposure to polycyclic aromatic hydrocarbons in C57BL/6 mice. Environmental Pollution, 2019,245:986-993
12. Runhua Wang, Lirong Gao*, Minghui Zheng, Jingguang Li*, Lei Zhang, YongningWu , GuoquanWang, Lipei Xiong, Danting Ding, Dasheng Lu, Lin Qiao, Lili Cui, Chi Xu, Characterization of short- and medium-chain chlorinated paraffins in cereals and legumes from 19 Chinese provinces. Chemosphere, 2019,226:282-289.
13. Hongjian Miao, Yue Huang, Chao Ma, Jingguang Li*, Yunfeng Zhao, Yongning Wu, Ultra-High-Performance Liquid Chromatography-Isotope Dilution Tandem Mass Spectrometry for the Determination of Phthalate Secondary Metabolites in Human Serum Based on Solid-Phase Extraction[J]. Journal of AOAC International, 2019,102:271-277.
14. Liu Xin; Zhang Lei; Li Jingguang*; Meng Guimin; Chi Min; Li Tiantian; Zhao Yunfeng; Wu Yongning, A nested case-control study of the association between exposure to polybrominated diphenyl ethers and the risk of gestational diabetes mellitus. Environment International, 2018,119:232-238.
15. Yuwei Wang, Yanmin Sun, Tian Chen, Zhixiong Shi*, Xianqing Zhou, Zhiwei Sun, Lei Zhang, Jingguang Li*, Determination of polybrominated diphenyl ethers and novel brominated flame retardants in human serum by gas chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry. Journal of Chromatography B, 2018,1099:64-72.
16. Huiting Huang, Lirong Gao*, Minghui Zheng , Jingguang Li*, Lei Zhang , Yongning Wu , Runhua Wang , Dan Xia, Lin Qiao, Lili Cui, Guijin Su , Wenbin Liu, Guorui Liu, Dietary exposure to short- and medium-chain chlorinated paraffins in meat and meat products from 20 provinces of China. Environmental Pollution, 2018,233:439-445.
17. Lin Qiao, Lirong Gao*, Minghui Zheng, Dan Xia, Jingguang Li,* Lei Zhang, Yongning Wu, Runhua Wang, Lili Cui, Chi Xu, Mass Fractions, Congener Group Patterns, and Placental Transfer of Short- and Medium-Chain Chlorinated Paraffins in Paired Maternal and Cord Serum. Environmental Science & Technology, 2018,52:10097-10103.
18. Lei Zhang, Xin Liu, Guimin Meng, Min Chi, Jingguang Li*, Shuaixing Yin, Yunfeng Zhao, Yongning Wu , Non-dioxin-like polychlorinated biphenyls in early pregnancy and risk of gestational diabetes mellitus. Environment International, 2018,115:127-132.
19. Yuxin Wang, Yuxin Zhong, Jingguang Li*, Jianqing Zhang, Bing Lyu, Yunfeng Zhao, Yongning Wu, Occurrence of perfluoroalkyl substances in matched human serum, urine, hair and nail. Journal of Environmental Sciences, 2018,67:191-197.
20. Zhixiong Shi*, Lei Zhang, Yunfeng Zhao , Zhiwei Sun, Xianqing Zhou, Jingguang Li*, Yongning Wu. A national survey of tetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenyl ether in human milk from China: Occurrence and exposure assessment. Science of The Total Environment, 2017,599-600:237-245.
21. Jiaying Liu, Jingguang Li,* Yongning Wu, Yunfeng Zhao, Fengji Luo, Shuming Li, Lin Yang, Elham K. Moez, Irina Dinu, and Jonathan W. Martin*, Bisphenol A Metabolites and Bisphenol S in Paired Maternal and Cord Serum. Environmental Science & Technology, 2017,51:2456-2463.
22. Lei Zhang, Yuxin Zhong, Xin Liu, Yan Bao, Yunfeng Zhao, YongningWu1 Zongwei Cai, Jingguang Li, Determination of polychlorinated dibenzo‐p‐dioxins and polychlorinated dibenzofurans, and dioxin‐like polychlorinated biphenyls in human serum using programmable‐temperature vaporization gas chromatography with high‐resolution mass spectrometry. Journal of Separation Science, 2017,40:3453-3461.
23. Zhixiong Shi, Lei Zhang, Yunfeng Zhao, Zhiwei Sun, Xianqing Zhou, Jingguang Li, Yongning Wu, Dietary exposure assessment of Chinese population to tetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenyl ether: Results of the 5th Chinese Total Diet Study. Environmental Pollution, 2017,229:539-547.
24. Yu Shi, Lin Yang, Jingguang Li*, Jianqiang Lai, Yuxin Wang, Yunfeng Zhao, Yongning Wu*, Occurrence of perfluoroalkyl substances in cord serum and association with growth indicators in newborns from Beijing. Chemosphere, 2017,169:396-402.
25. Lei Zhang, Shuaixing Yin, Yunfeng Zhao, Zhixiong Shi, Jingguang Li*, Yongning Wu Polybrominated diphenyl ethers and indicator polychlorinated biphenyls in human milk from China under the Stockholm Convention. Chemosphere, 2017,189:32-38.
26. Xiao Liu, Sheng Wen, Jingguang Li, Lei Zhang, Yunfeng Zhao, Yongning Wu A study on the levels of a polybrominated biphenyl in Chinese human milk samples collected in 2007 and 2011. Environmental Monitoring and Assessment, 2016,188:515.
27. LinYang,ZhenWang,YuShi,JingguangLi*,YuxinWang,YunfengZhao,YongningWu, ZongweiCai*, Human placental transfer of perfluoroalkyl acid precursors: Levels and profiles in paired maternal and cord serum. Chemosphere, 2016,144:1631-1638.
