姓名:李建科
性别:男
学历:博士研究生
职称:教授
职务:兼任省级学会理事长
工作单位:陕西师范大学,食品工程与营养科学学院
教育情况:
1979.9-1983.7:西北农林科技大学,动物医学专业,本科,学士。
1999.9-2000.7:西北农林科技大学,动物临床医学,硕士。
2003.9-2006.7:南京农业大学,食品科学,博士学位。
工作经历:
1983.7-1996.5:西北民族大学,食品科学与动物科学系,助教,讲师、副教授,系副主任。
1996.5-1998.10:山东农业大学,动物科技学院,副教授,硕士生导师,新兽药试验中心副主任。
1998.10-至今:陕西师范大学,食品工程与营养科学学院,院长(2007-2014),二级教授,博士研究导师。
所受奖项:
1.黄花棘豆、甘肃棘豆中毒病综合防治研究,1991年获甘肃省科技进步三等奖。
2.1992年国务院批准获得享受政府特殊津贴。
3.苹果浓缩汁中耐热菌的PCR快速检测技术,2006年获陕西省科技进步三等奖。
4.果汁中耐热菌ELISA快速检测新技术研究及其试剂盒创制,2016年获陕西省科学技术二等奖。
5. 耐热菌快速检测试剂盒创制及应用,2018年陕西省职工优秀科技创新成果银奖。
6. 优质牛奶安全生产、评估及其活性物质综合利用研究与示范,2018年获陕西省科学技术二等奖。
主要研究方向:
食品化学与营养学、食品毒理学与安全性评价、细胞分子营养学、食品加工副产物深度开发与高值化利用、膳食因素对肠道菌群及健康影响、天然产物功能成分的提取分离及生物活性等。
代表性著作:
Lin Du, Jianke Li*, Xitong Zhang, Lifang Wang, Weimin Zhang, Pomegranate peel polyphenols inhibits inflammation in LPS-induced RAW264.7 macrophages via the suppression of MAPKs activation. Journal of Functional Foods, 43(2018), 62-69. (SCI一区)
Ying Luo, Xiaojiao Liu, Jianke Li*, Updating techniques on controlling mycotoxins - A review. Food Control, 89(2018), 123-132. (SCI二区)
Jiamu Kang, Liu Liu,∗, Meihui Liu, Xiaoxia Wu, Jianke Li∗, Antibacterial activity of gallic acid against Shigella flexneri and its effect on biofilm formation by repressing mdoH gene expression,Food Control, 94(2018)147-154. (SCI 2区)
Liu, M.H., Wu, X.X., Li, J.K*., et al. The specific anti-biofilm effect of gallic acid on Staphylococcus aureus by regulating the expression of the ica operon. Food Control. 2017,73,613-618. (SCI二区)
Yingsha Liu, Jianke Li*, Lin Zhang, Xiaoxia Wu, Feng Wang. Development of colloidal gold-based immunochromatographic assay for rapid detection of Alicyclobacillus acidoterrestris in apple juice. CyTA-Journal of Food, 2017,15(3), 352-356.(SCI三区)
Zhao.S.J., Li.J.K*., Wang.L.F and Wu.X.X., Pomegranate peel polyphenols inhibit lipid accumulation and enhance cholesterol efflux in raw264.7 macrophages. Food & Function. 2016,7, 3201–3210. (SCI一区)
Ou Lv, Lifang Wang, Jianke Li*, Qianqian Ma,Wei Zhao, Effects of pomegranate peel polyphenols on lipid accumulation and cholesterol metabolic transformation in human hepatic cell L-02 via PPARγ-ABCA1/CYP 7A1 pathway. Food & Function, 2016, 7, 4976–4983. (SCI一区)
Song, B.B., Li, J., Li, J.K*., Pomegranate peel extract polyphenols induced apoptosis in human hepatoma cells by mitochondrial pathway. Food Chem. Toxicol. 2016, 93, 158-166. (SCI二区)
Jianke Li*, Xiaoye He, Mengying Li, Wei Zhao, Liu Liu, Xianghong Kong. Chemical fingerprint and quantitative analysis for quality control of polyphenols extracted from pomegranate peel by HPLC. Food Chemistry, 2015, 176: 7-11. (SCI二区)
Xiaoye He, Jianke Li*, Wei Zhao, Run Liu, Lin Zhang, Xianghong Kong. Chemical fingerprint analysis for quality control and identification of Ziyang green tea by HPLC. Food Chemistry, 2015, 171: 405-411. (SCI二区)
Run Liu, Jianke Li*, Yujiang Cheng, Tianbo Huo,Jiayi Xue,Yingli Liu. Effects of ellagic acid-rich extract of pomegranates peel on regulation of cholesterol metabolism and its molecular mechanism in hamsters. Food & Function, 2015, 6(3): 780-787. (SCI一区)
Wei Zhao, Jianke Li*, Xiaoye He, Ou Lv, Yujiang Cheng, Run Liu, In vitro steatosis hepatic cell model to compare the lipid-lowering effects of pomegranate peel polyphenols with several other plant polyphenols as well as its related cholesterol efflux mechanisms. Toxicology Reports, 2014, 1, 945–954. (SCI)
Jianke Li*, Ruirui Huang, Kai Xia, Liu Liu. Double antibodies sandwich enzyme-linked immunosorbent assay for the detection of Alicyclobacillus acidoterrestris in apple juice concentrate, Food Control, 40 (2014), 172-176. (SCI二区).
Jianke Li*, Kai Xia,Chaozhou Yu. Detection of Alicyclobacillus acidoterrestris in Apple Juice Concentrate by Enzyme-linked Immunosorbent Assay. Food Control, 30 (2013), 251-254.(SCI). (SCI二区)
《食品毒理学》,李建科主编,高等学校统编教材,中国计量出版社(中国质检出版社),北京,2007年第一版。