姓名：张磊
性别：男
学历：博士
职称：
工作单位：阿尔塔科技有限公司
教育情况：
1981-1985，南开大学化学系，学士
1985-1988，南开大学元素所，硕士
1992-1996，西班牙奥维多大学化学院，博士
1996-1998，西班牙奥维多大学化学院，博士后
1998-1999，葡萄牙里斯本高工，博士后
1999-2004，美国麻省州立大学医学院，博士后研究助理
工作经历：
1988-1992，南开大学元素所，助教、讲师
2004-2007，美国上市公司CytRx Corp 资深研究员
2007-2008，美国上市公司Epix Pharma 资深研究员
2008-至今， 美国 A ChemTek, Inc.，创始人、CSO
2011-至今， 阿尔塔科技有限公司，创始人、董事长、CSO
所受奖项：
天津市“千人计划”特聘专家
主要研究方向：
有机化学，药物化学，农药化学，医药、兽药、农药合成与分析研究，精细有机化学试剂与有机标准物质合成与分析研究，稳定同位素标记化合物合成及质谱应用研究
代表性著作：
专著：
1.庞国芳，张磊，等，《世界常用农药核磁谱图集-上、下册》，化工出版社，2018年
Oral Presentations：
1.张磊，食品安全检测中混标问题解析，2018年AOAC中国食品安全技术与标准研讨会，昆明，2018
2.张磊，食品检测中农兽药杂质与代谢物研究, 第一届全国食品安全检测仪器及应用会议，北京，2017
3.Lei Zhang，Applications of Chemical Purification Technique In Preparation of Reference Materials，BCEIA，Beijing，2017
4.张磊，标准品制备中的影响因素分析，饲料质量安全培训班，南昌，2017
5.张磊，农兽药杂质与代谢物研究，饲料质量安全培训班，济南，2017
6.张磊，中外试剂的标准对比分析，中国科学仪器发展年会，北京，2014
Publications:
1.Juling CHEN, Maomao WANG, Lei ZHANG，PREPARATION OF CHOLESTEROL REFERENCE MATERIAL，BCEIA，Beijing，2017
2.Maomao WANG, Zijuan Zhang, Juling CHEN, Yanbo JIA, Yin XU, Lei ZHANG, STUDIES ON STABILITY AND DEGRAGATION PRODUCT OF TRIAMCINOLONE IN METHANOL, BCEIA，Beijing，2017
3.于瑞林，杨立凤，张磊，环状二聚对苯二甲酸丁二醇酯的制备，中国化学试剂协会年会暨发展研讨会，北京，2013
4.张磊，环状三聚对苯二甲酸丁二醇酯的制备，中国化学试剂协会年会暨发展研讨会，北京，2013
5.Lei Zhang and John Y. Zhang. Microwave-Assisted, Boron Trichloride Mediated Acylation of Phenols – Synthesis of (o-Hydroxyaryl)(aryl)methanones and Xanthones. J. Comb. Chem. 2006, 8, 361-367.
6.Lei Zhang, Y. John Zhang, Microwave-assisted Synthesis of 8-Mercapto-3-methyl-7-alkylxanthines – An Improved Method. Tetrahedron Letters, 2006, 47, 775-778.
7.Lei Zhang and John Y. Zhang. Microwave-Assisted Synthesis of Salicylamide via BCl3 Mediated Coupling. J. Comb. Chem. 2005, 7, 622-626.
8.Dennis G. Sprous, John Zhang, Lei Zhang, Zhaolin Wang and Mark A. Tepper. Kinase inhibitor recognition by use of a multivariable QSAR model. J. Mol. Graphics Modell. 2006, 24, 278-295.
9.Lei Zhang, Tariq M. Rana. Solid-phase synthesis of a heterocyclic compound library. A new strategy to create diversity in heterocyclic scaffolds. J. Comb. Chem. 2004, 6, 457-459.
10. Lei Zhang, Zhiyong Cui, Biliang Zhang. An efficient synthesis of 3'-amino-3'-deoxyguanosine from guanosine. Helv. Chim. Acta 2003, 86, 703-710.
11.Biliang Zhang, Lei Zhang, Lele Sun and Zhiyong Cui. Synthesis of pCpCpA-3'-NH-phenylalanine as a ribosomal substrate. Org. Lett., 2002, 4, 3615-3618.
12.Zhiyong Cui, Lei Zhang and Biliang Zhang. Efficient synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine from adenosine and guanosine. Tetrahedron Letters, 2001, 42, 561-563.
13.Lei Zhang, Lele Sun, Zhiyong Cui, Robert L. Gottlieb, Biliang Zhang. 5'-Sulfhydryl-modified RNA: Initiator synthesis, in vitro transcription, and enzymatic incorporation. Bioconjugate Chem. 2001, 12, 939-948.
14.Lei Zhang, M. Fatima C. Guedes da Silva, Maxim L. Kuznetsov, M. Pilar Gamasa, Jose Gimeno, Joao J. R. Frausto da Silva, Armando J. L. Pombeiro. Synthesis, electrochemical and theoretical stidies of Fischer-type alkenyl-carbyne tungsten complexes. [(dppe)(CO)2(RNC)W{CCH=C-CH2CH2(CH2)nCH2}][BF4] (R = Alkyl, Aryl). Organometallics, 2001, 20, 2782-2793.
15.Lei Zhang, M. Pilar Gamasa, Jose Gimeno, M. Fatima C. Guedes da Silva, Armando J. L. Pombeeiro. Synthesis, structural characterization and electro-chemical studies of neutral alkenylcarbyne tungsten complexes bearing chelating bidentate and tridentate phosphines. Eur J. Inorg. Chem. 2000, 1707-1715.
16.Lei Zhang, M. Pilar Gamasa, Jose Gimeno, M. Fatima C. Guedes da Silva, Armando J. L. Pombeiro. Mono and dinuclear tungsten alkenyl-carbyne complexes bridged by cyanide and diisocyanide ligands: synthesis, electrochemical and 183W NMR studies. Eur J. Inorg. Chem. 2000, 341-350.
17.Lei Zhang, M. Pilar Gamasa, Jose Gimeno. [MoBr(CO)2{k2(P,P)-dppm}2][PF6] (dppm = Ph2PCH2PPh2). A seven coordinate molybdenum (II) – dicarbonyl complex showing a capped octahedron geometry. Anal. Quim., Int. Ed. 1998, 94, 84-87.
18.Rodrigo J. Carbajo, Lei Zhang, Fernando Lopez-Ortiz. 183W NMR study of alkenyl-carbyne and alkenyl-vinylidene tungsten complexes. Magn. Reson. Chem. 1998, 36, 807-814.
19.Lei Zhang, M. Pilar Gamasa, Jose Gimeno, Agustin Galindo, Antonio Tiripiccio. Synthesis and characterization of tungsten alkenyl-carbyne and alkenyl-ketenyl complexes containing dithio ligands. X-ray crystal structure and MO analysis of [(dppe){k3(S,C,S)-S2CPCy3}W {≡CCH=C-(CH2)3CH2}][BF4]. Organometallics, 1997, 16, 4099-4108.
20.Lei Zhang, M. Pilar Gamasa, Jose Gimeno, Rodrigo J. Carbajo, Fernando Lopez-Ortiz, Antonio Tiripiccio. Synthesis and characterization of tungsten alkenyl-carbyne complexes complexes [(dppe)(CO)2LW{≡CCH=CCH2CH2(CH2)nCH2}][BF4] (L = CO, MeCN, PMe3) and [(dppe)(CO)2 XW{≡CCH=CCH2CH2(CH2)n CH2}][BF4] (X = Cl, Br, I). X-ray crystal structure of [(dppe)(CO)2ClW≡C-CH=CCH2CH2CH2CH2][BF4] and 183W NMR studies. Organometallics, 1996, 15, 4274-4284.
21.Lei Zhang, Jose Gimeno, M. Pilar Gamasa, Antonio Tiripiccio. Synthesis and characterization of novel alkenylcarbonyl-nitrosyl molybdenum (0) and tungsten (0) complexes. Crystal structure of [Mo(C≡CPrn)(CO)2(dppe)(NO)] [dppe = 1,2-bis(diphenylphosphino)ethane]. J. Organomet. Chem., 1996, 514, 287-297.
22.Lei Zhang, M. Fatima C. Guedes da Silva, Armando J. L. Pombeiro, M. P. Gamasa, J. Gimeno. Mo or W Complexes with 4e- or 2e-Donor Alkenylalkyne Ligands. International Conference on Organometallis and Catalysis. Sept. 1999, Rennes, France.
23.Lei Zhang, M. Pilar Gamasa, Jose Gimeno, Armando J. L. Pombeiro. Synthesis and Electrochemical Studies of Novel Carbene and Carbyne Tungsten Complexes. XXXIII International Conference on Coordination Chemistry, Aug 30-Sept 4, 1998, Florence, Italy.
24.Rodrigo J. Carbajo, Lei Zhang, Fernando Lopez-Ortiz. 183-W RMN en Complejos Alquenil-Carbino y Alquenil-Vinilideno. XVI National Spectrascopy Meeting, Sept 1998, Sevilla, Spain.
25.Lei Zhang, M. P. Gamasa, J. Gimeno, M. Fatima C. Guedes da Silva, Armando J. L. Pombeiro. Synthesis and Electrochemical Studies of Cyanide and Diisocyanide Bridged Fischer Type Dinuclear Bis(alkenyl-carnyne)tungsten Complexes. International School of Organometallic Chemistry, Sept 9-13, 1997, Camerino, Italy.
26.J. Gimeno, M.P. Gamasa, L. Zhang, A. Tiripiccio, M. Lanfranchi. Sintesis y Reactividad de Carbinos α,β–Insaturados de Wolframio. XV Reunion del Grupo Especializados de Quimica Organometalica. Sept 20-22, 1995, Sevilla, Spain.
27.J. Gimeno, M.P. Gamasa, L. Zhang, A. Tiripiccio, M. Lanfranchi. Synthesis and Reactivity of Unsaturated Carbene and Carbyne Tungsten Complexes. XIth FECHEM Conference on Organometallic Chemistry. Sept 10-15, 1995, Parma, Italy.
28.M.P. Gamasa, J. Gimeno, Lei Zhang, A. Tiripiccio, M. Lanfranchi. Synthesis and Reactivity of New Alkynyl Nitrosyl Molybdenum and Tungsten Complexes. Latin-American Inorganic Chemistry Meeting. Sept 13-17, 1993, Santiago de Compostela, Spain.
29.Chen Qi-jie, Zhang Lei. Studies on the Synthesis and Bioactivity of Thienoxazaphos-pholane S,S-Dioxides. First National Conference of Organophosphorous Chemistry, Sept 1988, Beijing, China.
