姓名:沈新春

性别:

学历:博士研究生

职称:教授

工作单位:南京财经大学

 

教育情况:

20003  博士(工学)  日本东京大学化学生命工程专业

19973  硕士(工学)  日本东京大学化学生命工程专业

19877  学士(工学)  南京粮食经济学院粮油贮藏专业

 

工作经历:

2012/08-至今,南京财经大学,食品科学与工程学院,教授

2005/07-2012/07,美国北卡罗来纳大学教堂山分校,医学院McAllister心脏研究院,助理研究员

2003/10-2005/07,美国北卡罗来纳大学教堂山分校,药学院基因组学研究中心,博士后研究员

2002/07-2003/09,美国堪萨斯州立大学,食品科学系,博士后研究员

2000/04-2002/07,日本理化学研究所(RIKEN),基因组学研究中心(GSC)蛋白质结构和功能研究组,研究员

1987/07-1993/09,南京粮食经济学院,粮油贮藏系,讲师

 

所受奖项:

中国商业联合会科技进步奖一等奖, 20164/15

科学中国人 (2014) 年度人物, 2015

The Endocrine Society Outstanding Abstract Award, 2011

The Endocrine Society Travel Grant Award, 2011

The Endocrine Society Travel Grant Award, 2009  

The Endocrine Society Travel Grant Award, 2007

 

主要研究方向:

分子营养与 功能性食品
农产品深加工与副产品综合利用
食品质量与安全

 

代表性著作:

1.  Haijuan Chen, Zheng Xu, Jialu Mo,  Yi Lyu, Xiaozhi Tang, Xinchun Shen, Effects of guar gum on adhesion properties of soybean protein isolate onto porcine bones. International Journal of Adhesion and Adhesives, 2017, 75: 124-131. (Correspondence author)

2.  Xiaozhou Cao, Yi Lyu, Junyu Ning, Xiaozhi Tang, Xinchun Shen, Synthetic peptide, Ala-Arg-Glu-Gly-Glu-Met, abolishes pro-proliferative and anti-apoptotic effects of high glucose in vascular smooth muscle cells. Biochemical and Biophysical Research Communications, 2017, 485: 215–220. (Correspondence author)

3.  Siyuan Chen, Dingbo Lin, Yulong Gao, Xiaozhou Cao, Xinchun Shen, A novel antioxidant peptide derived from wheat germ prevents high glucose-induced oxidative stress in vascular smooth muscle cells in vitro. Food & Function. 2017, 8: 142-150. (Correspondence author)

4.  Chen Yu, Junfei Liu, Xiaozhi Tang, Xinchun Shen, Shaowei Liu, Correlations between the physical properties and chemical bonds of extruded corn starch enriched with whey protein concentrate. RSC Advances, 2017, 7: 11979-11986

5.  Gang Xi, Xinchun Shen, Clifford J. Rosen, David R Clemmons, IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation. Journal of Bone and Mineral Research, 2016, 31(6):1300-1314

6.  Xinchun Shen, Gang Xi, Christine Wai, David R Clemmons, The Coordinate Cellular Response to Insulin-Like Growth Factor-I (IGF-I) and Insulin-Like Growth Factor Binding Protein-2 (IGFBP-2) Is Regulated Through Vimentin Binding to Receptor Tyrosine Phosphatase β (RPTPβ). Journal of Biological Chemistry, 2015, 290: 11578-90

7. Gang Xi§, Xinchun Shen§, Christine Wai, Caroline K. Vilas, David R Clemmons, Hyperglycemia stimulates p62/PKC? interaction, which mediates NF-?? activation, increased Nox4 expression, and inflammatory cytokine activation in vascular smooth muscle. The FASEB Journal, 2015, 29: 4772-4782 (§并列第一作者)

8.  Xinchun Shen*, Yuan Chen, Heng Ge, Combinatory Use of Cell-free Protein Expression, Limited Proteolysis and Mass Spectrometry for the High-throughput domain Boundary Identification. Biochemical and Biophysical Research Communications, 2014, 444: 480-484. (*Correspondence author)

9.  Gang Xi, Xinchun Shen, Christine Wai, and David Clemmons. Recruitment of Nox4 to a plasma membrane scaffold is required for localized reactive oxygen species generation and sustained Src activation in response to insulin-like growth factor-I. Journal of Biological Chemistry, 2013, 288: 15641-15653.

10. Xinchun Shen, Gang Xi, Laura A Maile, Christine Wai, Clifford J Rosen, David R Clemmons, Insulin-like growth factor binding protein-2 functions coordinately with receptor protein tyrosine phosphatase β and the IGF-I receptor to regulate IGF-I-stimulated signaling. Molecular and Cellular Biology, 2012, 32: 4116-30.

 

[1]张逸婧,刘永祥,陈思远,陈海娟,张云璐,周建新,沈新春. 脱脂溶剂对大豆分离蛋白、7S11S球蛋白提取率及纯度的影响[J]. 中国油脂,2016,02:30-33.

 

 

 

 

[2]张逸婧,陈海娟,吕奕,刘永祥,汤晓智,沈新春. 羧甲基纤维素钠对大豆分离蛋白骨粘合性能的影响[J]. 中国农业科学,2016,08:1550-1558.

 

[3]张逸婧 大豆分离蛋白胶骨粘合性能的研究, 2016 天然产物研究与开发

 

[4]陈思远,刘永祥,曹小舟,张逸婧,陈海娟,沈新春. 从麦胚清蛋白分离制备高活性抗氧化肽[J]. 中国农业科学,2016,12:2379-2388.

 

[5]刘永祥,张逸婧,陈思远,周建新,沈新春. 响应面法优化麦胚清蛋白制备抗氧化肽的酶解工艺[J]. 食品工业,2016,05:88-93.

[6]曹小舟,刘永祥,俞凌,苏安祥,沈新春. 植物蛋白源抗氧化肽活性的评价方法及作用机制的研究进展[J]. 食品工业科技,2016,13:355-359+364.

[7] 曹小舟 小麦胚芽抗氧化肽对高糖诱导的血管平滑肌细胞增殖的保护作用 食品工业科技 2016

[8]刘永祥,陈思远,张逸婧,曹小舟,陈海娟,沈新春.  麦胚无细胞蛋白合成系统研究进展[J]. 食品工业科技. 食品工业科技,20153617):379-383