姓名:史贤明

性别:

学历:博士

职称:教授

工作单位:上海交通大学农业与生物学院

 

教育情况:

1994.11-1998.03,香港大学,生物技术,理学博士

1985.09-1988.06,华中农业大学,微生物学,农学硕士

1978.10-1982.08,华中农业大学,微生物学,农学学士

 

工作经历:

2004.02-现在,上海交通大学农业与生物学院,教授、博导、系主任(2015-2018)、中美食品安全联合研究中心主任(2008-现在)

2014.01-08,美国罗格斯大学食品科学系,资深访问教授

2007.07-08,美国农业部东部研究中心,访问教授

1988.07-2004.01,华中农业大学食品科技系(学院),讲师、教授、博导、食品安全与微生物系主任,农业微生物学国家重点实验室食品微生物分室主任、农业部食品安全重点实验室副主任

2003.01-08,美国康奈尔大学食品科学系,访问教授

1998.08-11,香港大学理学院植物学系,访问教授

1993.10-1994.10,美国华盛顿大学医学院微生物学系,访问学者

1982.08-1985.08,农业部环保所,团委书记、实习研究员

 

所主持的项目及其进展:

20221-202512月,国家自然基金科学基金面上项目,32172316 RNA DsrA介导鼠伤寒沙门氏菌形成过氧化氢抗性的分子机制,58万元,在研

202012-202311月,国家重点研发计划政府间国际科技创新合作专项,2019YFE0119700,基于基因组的耐药沙门氏菌智能检测系统的构建及其在中美间传播风险的评估,370万,在研

201911-202210月,上海市科技创新行动计划农业领域项目,19391902100,即食蔬菜中主要食源性致病菌量子点快速检测芯片的研发,60万元,在研

201612-201911月,国家重点研发计划政府间国际科技创新合作重点专项,2016YFE0106100,食源性致病微生物快速检测与精准分析技术的研发及应用,385.2万元,已结题

201301-201712月,国家自然基金重点项目,31230058,鸡蛋贮藏过程中肠炎沙门氏菌生存与增殖的抗逆分子机制,295万元,已结题

201201-201512月,国家863项目,2012AA101601,食品中有害微生物精确检测与快速分型技术,771万元,已结题

 

所受奖项:

2019年,中国食品科学技术学会突出贡献奖

2016年,国际食品科学院(IAFoST)院士(Fellow

2013年,国际食品科学认证委员会授予的“Certified Food Scientist”

 

主要研究方向:

1.     食品安全

2.     食源性细菌分子生态

 

代表性著作:

1) 史贤明(主编). 2003. 《食品安全与卫生学》(面向二十一世纪课程教材). 中国农业出版社, 北京.

2) He, S., Qin, X., Wong, C., Shi, C., Wang, S*, Shi, X*. Ethanol adaptation strategies in Salmonella enterica serovar Enteritidis revealed by global proteomic and mutagenic analyses. Applied and Environmental Microbiology, 2019, 85: e01107-19.

3) Huang, X., Zhou, X., Jia, B., Li, N., Jia, J., He, M., He, Y., Qin, X., Cui, Y., Shi, C., Liu, Y., Shi, X*. Transcriptional sequencing uncovers survival mechanisms of Salmonella enterica serovar Enteritidis in antibacterial egg white. mSphere, 2019, 4: e00700-18.

4) Qin, X., He, S., Zhou, X., Cheng, X., Huang, X., Wang, Y., Wang, S., Cui, Y., Shi, C., Shi, X*. Quantitative proteomics reveals the crucial role of YbgC for Salmonella enterica serovar Enteritidis survival in egg white. International Journal of Food Microbiology, 2019, 289: 115-126.

5) Zhang, Z., Liu, D., Bai, Y., Cui, Y., Wang, D., Shi, X*.  Identification and characterization of two high affinity aptamers specific for Salmonella Enteritidis. Food Control, 2019,106: 106719.

6) Bai, Y., Cui, Y., Suo, Y., Shi, C., Wang, D., Shi, X*. A rapid method for detection of Salmonella in milk based on extraction of mRNA using magnetic capture probes and RT-qPCR. Frontiers in Microbiology, 2019, 10: 770.

7) Ye, B#., He, S#., Zhou, X., Cui, Y., Zhou, M., Shi, X*. Response to acid adaptation in Salmonella enterica serovar Enteritidis. Journal of Food Science, 2019, 84: 599-605.

8) Huang, X., Hu, M., Zhou, X., Liu, Y., Shi, C., Shi, X*. Role of yoaE Gene Regulated by CpxR in the Survival of Salmonella enterica Serovar Enteritidis in Antibacterial Egg. mSphere, 2020, 5:1–10.

9) Zhang, Z., Yang, J., Xu, X., Zhou, X., Shi, C., Zhao, X., Liu, Y., Shi, X*. Co-existence of mphA, oqxAB and blaCTX-M-65 on the IncHI2 plasmid in highly drug-resistant Salmonella enterica serovar Indiana ST17 isolated from retail foods and humans in China. Food Control, 2020:107269.

10) Qin, X., Dong, R., He, S., Zhou, X., Zhang, Z., Cui, Y., Shi, C., Liu,Y., Shi, X*. Characterization of the role of ybgC in lysozyme resistance of Salmonella Enteritidis. Food Control, 2020, 109:106732.

11) Yang, J., Zhang, Z., Zhou, X., Cui, Y., Shi, C., Shi, X*. Prevalence and characterization of antimicrobial resistance in Salmonella enterica isolates from retail foods in Shanghai, China. Foodborne Pathogens and Disease, 2020, 17(1), 35-43.

12) Zhou, X., Liu, B, Liu,Y., Shi, C., Fratamico, P., Zhang, L., Wang, D., Zhang, J., Cui, Y., Xu, P., Shi, X*. Two homologous Salmonella serogroup C1-specific genes are required for flagellar motility and cell invasion. BMC Genomics, 2021, 22:507.

13) He, S., Fong, K., Wang, S.*, Shi, X*. Ethanol adaptation in foodborne bacterial pathogens. Critical reviews in food science and nutrition, 2021, 61(5): 777-787.

14) He, S., Shi, X*. Microbial Food Safety in China: Past, Present, and Future. Foodborne Pathogens and Disease, 2021, 18(8): 510-518.

15) Zhang, Z., Chang, J., Xu, X., Zhou, M., Shi, C., Liu, Y., Shi, X*. Dissemination of IncFII plasmids carrying fosA3 and blaCTX-M-55 in clinical isolates of Salmonella Enteritidis. Zoonoses and Public Health, 2021, 00: 1-9.

16) Zhu, J., Zhang, D., Zhou, X., Cui, Y., Jiao, S., Shi, X*. Development of a pasteurization method based on radio frequency heating to ensure microbiological safety of liquid egg. Food Control, 2021, 123, 107035.

17) Li, C., Zhang, Z., Xu, X., He, S., Zhao, X., Cui, Y., Zhou, X., Shi, C., Liu, Y., Zhou, M., Shi, X*. Molecular Characterization of cephalosporin-resistant Salmonella Enteritidis ST11 isolates carrying blaCTX-M from children with diarrhea. Foodborne Pathogens and Disease, 2021, 10(18):702-711.

18) Dong, R., Qin, X., He, S., Zhou, X., Cui, Y., Shi, C., He, Y., Shi, X*. DsrA confers resistance to oxidative stress in Salmonella enterica serovar Typhimurium. Food Control, 2021:107571.

19) Zhang, Z., He, S., Yang, B., Shi, C., Liu, Y., Shi, X*. Genomic characterization of an extensively drug-resistant chicken-borne Salmonella Indiana isolate carrying an IncHI2-IncHI2A plasmid. Food Control, 2021, 125: 107761.