姓名:詹晓北

性别:

学历:博士

职称:教授

工作单位:江南大学食品学院

 

教育情况:

19831987分别获得无锡轻工业大学发酵工程专业本科和硕士学位,2004年获得美国Kansans State University 博士学位

 

 

工作经历:

1987-09~1997-09             中国      无锡轻工大学                         讲师

1997-09~2004-12             中国      江南大学                                 副教授

2001-06~2004-12             美国      美国Kansas State University         博士

2004-12~2008-10             中国      江南大学                                 教授

2008-10~2009-10             美国      美国Emory University                   高访

2009-10~2011-05              美国      美国Kingwason LLC             总工/股东

2011-05~                           中国      江南大学                          中心主任

 

所受奖项:

[入选人才项目]

国家级

2005 国家注册化工工程师资格

2005教育部长江学者与创新团队主要承担人

2012年入选中组部千人计划

省部级

2002年,江苏高校青蓝工程中青年学术带头人

2006, “无锡市学术技术带头人培养工程

2011年,入选无锡市“130”计划

2013年入选内蒙古草原英才

2013年入选江苏省双创人才

[科研与奖励]

2010年获得中国食品科技协会科技进步三等奖食品级微生物多糖发酵关键技术(排名第一)。

2002年完成的“20000/时纯生啤酒瓶装生产线获广东省科学技术二等奖(排名第三)。

1998年主持完成的冰啤酒及冷冻浓缩成套设备生产冰啤酒新技术项目获安徽省科学技术进步四等奖(排名第一)。

1991年研究的高粘度流体黄原胶生物反应器项目获得轻工业部科技进步三等奖(排名第二)

 

主要研究方向:

二十多年来一直致力于微生物多、寡糖的理论和生产应用研究,在微生物菌种育种、生物过程优化、生物聚合物工程等方面积累了丰富理论知识和实践经验。主要研究方向是:高粘度发酵技术;微生物多糖生物合成;功能性寡糖制备;生物反应器;传统发酵食品

 

代表性著作:

1 Optimization of conditions for the production of pullulan and high molecular weight pullulan by Aureobasidium pullulans

2 Production of polysialic acid from fed-batch fermentation with pH control

3 Ethanol and lactic acid production as affected by sorghum genotype and location

4 Ethanol production from supercritical-fluid-extrusion cooked sorghum

5 Effect of metabolic structures and energy requirements on curdlan production byAlcaligenes faecalis

6 Construction of a flocculating yeast for fuel ethanol production

7 Improvement of hEGF production with enhanced cell division ability using dissolved oxygen responses to pulse addition of tryptone

8 A new strategy to enhance polysialic acid production by controlling sorbitol concentration in cultivation of Escherichia coli K235

9 An efficient and large-scale preparation process for polysialic acid by Escherichia coli CCTCC M208088

10 Enhancement of polysialic acid yield by reducing initial phosphate and feeding ammonia water to Escherichia coli CCTCC M208088

11 Improvement of the CuZn-superoxide dismutase enzyme activity and stability as a therapeutic agent by modification with polysialic acids

12 Improvement of ATP regeneration efficiency and operation stability in porcine interferon-α production by Pichia pastoris under lower induction temperature

13 Enhanced curdlan production in Agrobacterium sp. ATCC 31749 by addition of low-polyphosphates 

14 Component identification of electron transport chains in curdlan-producing Agrobacterium sp. ATCC 31749 and its genome-specific prediction using comparative genome and phylogenetic trees analysis

15 Changes of curdlan biosynthesis and nitrogenous compounds utilization characterized in ntrC mutant of Agrobacterium sp. ATCC 31749

16 Sequence and transcriptional analysis of the genes responsible for curdlan biosynthesis in Agrobacterium sp. ATCC 31749 under simulated dissolved oxygen

17 Changes in gene transcription and protein expression involved in the response of Agrobacterium sp ATCC 31749 to nitrogen availability during curdlan production

18 Methanol/sorbitol co-feeding induction enhanced porcine interferon-α production by P. pastoris associated with energy metabolism shift

19 Improvement of specific growth rate of Pichia pastoris for effective porcine interferon-α production with an on-line model-based glycerol feeding strategy

20 Recent advances in curdlan biosynthesis, biotechnological production, and applications 

21 NtrC-dependent regulatory network for curdlan biosynthesis in response to nitrogen limitation in Agrobacterium sp. ATCC 31749

22 Identification and analysis of the metabolic functions of a high-salt-tolerant halophilic aromatic yeast Candida etchellsii for soy sauce production

23 An unstructured kinetic model to study NaCl effect on volatile ester fermentation by Candida etchellsii for soy sauce production

24 Structure of oligosaccharide F21 derived from exopolysaccharide WL-26 produced by Sphingomonas sp. ATCC 31555

25 A two-step inoculation of Candida etchellsii to enhance soy sauce flavour and quality

26 Improved curdlan fermentation process based on optimization of dissolved oxygen combined with pH control and metabolic characterization of Agrobacterium sp.ATCC 31749

27 Typing of Blood-Group Antigens on Neutral Oligosaccharides by Negative-Ion Electrospray Ionization Tandem Mass Spectrometry

28 Enhancing pIFN-α Production and Process Stability in Fed-Batch Culture of Pichia pastoris by Controlling the Methanol Concentration and Monitoring the Responses 

29 A new polysialic acid production process based on dual-stage pH control and fed-batch fermentation for higher yield and resulting high molecular weight product

30 New Model for Flavour Quality Evaluation of Soy Sauce

31 Influence of sodium chloride on thermal denaturation of a high-salt-tolerant neutral protease from Aspergillus oryzae

32 A new effective process for production of curdlan oligosaccharides based on alkali-neutralization treatment and acid hydrolysis of curdlan particles in water suspension. 

33 A novel osmotic pressure control fed-batch fermentation strategy for improvement of erythritol production by Yarrowia lipolytica from glycerol