Name: ZHUGE Bin
Gender: Male
Degree: Ph.D.
Title: Professor
Organization: Jiangnan University
Education Experience:
March,2003－March ,2007: Jiangnan University, PhD candidate. PhD
March,1999－July, 2001: Wuxi University of Light Industry, Graduate student (Master’s degree)
September, 1987－July,1990: Department of Applying Chemistry, Jiangnan University, Majored in Environment Protection Engineering, Undergraduate
Work Experience:
2010-now: School of Biotechnology, Jiangnan University, Professor
2004－2009: School of Biotechnology, Jiangnan University, Associate professor
2001－2004: School of Biotechnology, Jiangnan, Lecturer
1993－2001: Department of Applying Chemistry in Jiangnan College, Lecturer
Rewards:
The first prize of 2008 Scientific and Technological Progress Awards of Chinese Cereals and Oils Association (CCOA)。
The third prize of Scientific and Technological Progress Awards of China National Light Industry Council (CNLIC)
The first prize of 1997 Award of Science & Technology of China Ministry of Light Industry
Research Area:
Microbiolog、Biotechnology、Biochemistry、Flavouring
Publication:
1. Zhuge B, Fang HY, Yu H, Rao ZM, Shen W, Song J, Zhuge J (2008) Bioconversion of lovastatin to a novel statin by Amycolatopsis sp. Applied Microbiology and Biotechnology 79:209-216
2. Zhuge B, Du GC, Shen W, Zhuge J, Chen J (2007) Expression of a Bacillus subtilis pectate lyase gene in Pichia pastoris. Biochemical Engineering Journal 40(1):92-98
3. Bin Zhuge, Guo-Cheng Du, Wei Shen, Jian Zhuge,Jian Chen(2007). Efficient secretory expression of an alkaline pectate lyase gene from Bacillus subtilis in E.coil and the purification and characterization of the protein. Biotechnology letters. 29: 405-410
4. Bin Zhuge， Cheng Zhang ， Huiying Fang ，Jian Zhuge ， Kugen Permaul (2010) Expression of 1,3-propanediol oxidoreductase and its isoenzyme in Klebsiella pneumoniae for bioconversion of glycerol into 1,3-propanediol Applied Microbiology and Biotechnology 87:2177-2218
5. Bin Zhuge, Xue-Na Guo, Crispen Mawadza, Hui-Ying Fang, Xue-Ming Tang, Xi-Hong Zhang and Jiang Zhuge. A Novel Candida glycerinogenes Mutant with High Glycerol Productivity in High Phosphate Concentration Medium World Journal of Microbiology & Biotechnology (2005) 21:453-456
6. Chen X, Fang H, Rao Z, Shen W, Zhuge B, Wang Z, Zhuge J. Cloning and characterization of a NAD( )-dependent glycerol-3-phosphate dehydrogenase gene from Candida glycerinogenes, an industrial glycerol producer。FEMS Yeast Res. 2008 8(5):725-734
7. Chen X, Fang H, Rao Z, Shen W, Zhuge B, Wang Z, Zhuge J.An efficient genetic transformation method for glycerol producer Candida glycerinogenes. Microbiol Res. 2008;163(5):531-537.
8. Ma Z, Rao Z, Zhuge B, Fang H, Liao X, Zhuge J.Construction of a novel expression system in Klebsiella pneumoniae and its application for 1,3-propanediol production.Appl Biochem Biotechnol. 2010;162(2):399-407.
9. T. Xie, H. Y. Fang, B.Zhuge, and J. Zhuge Promotional Mechanism of High Glycerol Productivity in the Aerobic Batch Fermentation of Candida glycerinogenes after Feeding Several Amino Acids Applied Biochemistry and Microbiology,2009,45(3):303–308
10. Ma Z, Rao Z, Xu L, Liao X, Fang H, Zhuge B, Zhuge J Expression of dha operon required for 1,3-PD formation in Escherichia coli and Saccharomyces cerevisiae.Curr Microbiol. 2010;60(3):191-198
11. Zhuge B, Du GC, Shen W, Zhuge J, Chen J (2006). Construction of an engineering strain producing alkaline pectate lyase with pHSh.Wei Sheng Wu Xue Bao. 46(4):657-9. Chinese
12. Zhuge B, Du GC, Zhuge J, Chen J(2008) Properties of alkaline pectate lyase from recombinant strain E. coli JM109 (pHsh PL), ACTA MICROBIOLOGICA SINICA 48 (1):121-125
13. Zhuge B, Du GC, Zhuge J, Chen J(2008) Optimization of Culture Conditions for Alkaline Pectate Lyase Production by Recombinant Pichia pastoris. Chin J Appl Environ Biol 14(4):539~543
14. Zhuge B, Du GC, Shen W, Chen J(2006), Construction of Engineering strain producing Pectate lyase, Chin J Appl Environ Biol 12(4): 547-549
15. Zhang XM, Zhuge B, Xie T, Tang XM, Fang HY, Zhuge J(2006),Construction of novel recombinant Escherichia coli capable of producing 1,3-propanediol and its conversion of glycerol. Journal of Chemical Industry and Engineering(CHINA) 57(12):2920-2925. Chinese.
16. Zhang XM, Tang XM, Zhuge B, Shen W, Rao ZM, Fang HY, Zhuge J(2005) Construction of Novel Recombinant Escherichia coli Capable of Producing 1,3-propanediol. Chinese Journal of Biotechnology 21(5):743-747. Chinese.
17. Zhuge B, Qian XM, Fang HY, Zhuge J(2004), Study on Quick Determination of Glycerol in Fermented Broth. Food and Fermentation Industries 30(8):101-103. Chinese.
18. Liu JW, Zhuge B, Zhang YB, Zhuge J(2004), Pretreatment of wastewater from glycerol extraction process by Fenton’s reagent. Techniques and Equipment for Environmental Pollution Control 5(9):82-85. Chinese.
19. Liu GX, Yu BQ, Zhuge B, Zhuge J(2003) The Two Isoenzyme of S. cerevisiae 3-phosphate Dehydrogenase. Microbiology 30(5):106-110. Chinese.
20. Guo X, Zhuge B, Zhuge J(2002). Research progress on the glycerol kinase.Wei Sheng Wu Xue Bao.42(4):510-3. Review. Chinese.
21. Guo XN， Zhuge B， Qiu CY， Zhuge J(2002) Screening Candida glycerolgeneses Mutants with High Productivity and the Fermentation Perform ance of the Mutants. Journal of Wuxi University of Light Industry 21(4):336-339. Chinese.
22. Zhuge B，Yao HY，Zhuge J(2002) The Optimization of Culture Medium for Raw-starch Enzyme Producer- Rhizopus OR-1UVN. Food and Fermentation Industries 28(7):29-33. Chinese.
23. Zhuge B，Yao HY，Zhuge J(2002) Studies on amino acid residues in the active site of raw-starch enzyme and regulation of the enzyme synthesis of Rhizopus OR-1UVN. Industrial Microbiology 32(3):24-27. Chinese.
24. Zhuge B，Yao HY，Zhuge J(2001) Screening and mutating a raw starch-digesting glucoamylase strain. Microbiology 28(6):60-64. Chinese.
