Name: GAO Fu
Gender: Male
Degree: Doctor
Title: Professor
Organization: Chinese Center for Disease Control and Prevention
Education Experience:
Professor George F. Gao obtained his Ph.D (DPhil) degree from Oxford University, UK and did his postdoc work in both Oxford University and Harvard University (with a brief stay in Calgary Universty).
Rewards:
1988 Young Scientist Award—China Association for Science and Technology
1991 Sino British Friendship Scholarship Scheme (SBFSS) Fellowship of the
British Council
1998 UK Wellcome Trust International Travelling Fellowship
2002 National Natural Science Foundation of China (NSFC) “Overseas
Outstanding Young Scientist “
2003 Ministry of Education P. R. China “Chun Hui Project”
2004 Chinese Academy of Sciences (CAS) “Hundred-talent Project”
2005 Chief Scientist MOST 973 Project
2005 National Natural Science Foundation of China (NSFC) Distinguished
Young Investigator
2006 New century Candidate of National project “thousands of talents”. (Awarded
by Ministry of Personnel of the People’s Republic of China)
2007 Science & Technology Award of 5th Dabeinong
2008 Thomson Reuters Research Fronts Award 2008
2008 Supervisor of Excellent Postgraduate of CAS
2009 Award for Life Science Innovation “Tan Jia Zhen Award”
2009 “Zhuli Yuehua” Outstanding Supervisor of CAS
2010 “Overseas Chinese (innovative talents) contribution” Award of China
Federation of Returned Overseas
2010 Supervisor of Excellent Postgraduate of CAS
2010 Chief Scientist MOST 973 Project
Research Area:
Molecular mechanism of interspecies transmission of emerging/re-emerging pathogens and structural immunology, esp. on T cell molecular recognition, the molecular mechanism of enveloped virus (such as HIV virus) fusion and entry, and molecular mechanism of interspecies transmission of animal-borne pathogens (such as bird flu virus).
Publication:
He has over 140 publications in the related fields involved in Nature, Nature Medicine, Nature Structural and Molecular Biology, Science, Lancet, PNAS-USA, PLoS Medicine, Journal of Immunology, Journal of Virology, Journal of Infectious Diseases, J. Exp. Med., JBC, etc.
1. Li#, Q., Qi#, J., Zhang, W., Vavricka, C. J., Shi, Y., Wei, J., Feng, E., Shen, J., Chen, J., Liu, D., He, J., Yan, J., Liu, H., Jiang, H., Teng, M., Li, X., Gao*, G. F., 2010, The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site. Nature Structural and Molecular Biology.17 (10): 1266-1268.
2. Liu, J., Sun, Y., Qi, J., Chu, F., Wu, H., Gao, F., Li, T., Yan, J., Gao*, G. F., 2010, Membrane protein of SARS-CoV acts as a dominant immunogen revealed by a clustering region of novel functional and structural defined CTL epitopes. The Journal of Infectious Diseases. 202 (8): 1171-1180.
3. Feng*, Y., Zhang, H., Ma, Y., Gao*, G. F., 2010, Uncovering newly emerging variants of Streptococcus suis, an important zoonotic agent. Trends in Microbiology, 18 (3): 124-131.
4. Zhou#, Z., Jiang#, X., Liu, D., Fan, Z., Hu, X., Yan, J., Wang, M., Gao*, G. F., 2009, Autophagy is involved in influenza A virus replication. Autophagy, 5 (3): 321-328.
5. Chu, F. L., Lou, Z., Chen, Y. W., Liu, Y., Zong, L., Gao, B., Khan, A. H., Bell, J. I., Rao, Z., Gao*, G. F., 2007, First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape. The Journal of Immunology, 178 (2): 944-952.
6. Tang*#, J., Wang#, C., Feng#, Y., Yang#, W., Song#, H., Chen#, Z., Yu#, H., Pan, X., Zhou, X., Wang, H., Wu, B., Wang, H., Zhao, H., Lin, Y., Yue, J., Wu, Z., He, X., Gao, F., Khan, A. H., Wang, J., Zhao, G. P., Wang*, Y., Wang*, X., Chen, Z., Gao*, G. F., 2006, Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2. PLoS Medicine，3 (5): 668-676.
7. Liu*#, J., Xiao#, H., Lei#, F., Zhu, Q., Qin, K., Zhang, X. W., Zhang, X. L., Zhao, D., Wang, G., Feng, Y., Ma, J., Liu, W., Wang, J., Gao*, G. F., 2005, Highly pathogenic H5N1 influenza virus infection in migratory birds. Science, 309 (5738): 1206.
8. Gao,* G. F., Rao, Z. & Bell, J. I., 2002, Molecular coordination of cβ T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands. Trends in Immunology, 23: 408-413.
9. Meng, S. D., Gao, T., Gao, G. F. & Tien*, P., 2001, HBV-specific peptide associated with heat-shock protein gp96. The Lancet, 357 (9255): 528-529.
10. Wyer* J. R., Willcox*, B. E., Gao*, G. F., Gerth, U. C., Davis, S. J. , Bell, J. I. , van der Merwe, P. A. & Jakobsen, B. K. , 1999, T cell receptor and coreceptor CD8 αα bind peptide-MHC independently and with distinct kinetics. Immunity, 10 (2): 219-225.
11. Willcox*, B. E., Gao*, G. F., Wyer, J. R., Ladbury, J. E., Bell, J. I., Jakobsen, B. K. & van der Merwe, P. A., 1999, TCR binding to peptide-MHC stabilizes a flexible recognition interface. Immunity, 10 (3): 357-365.
12. Gao, G. F., Tormo, J., Gerth, U. C., Wyer, J. R., McMichael, A. J., Stuart, D. I., Bell, J. I., Jones, E. Y. & Jakobsen, B. K., 1997, Crystal structure of the complex between human CD8 αα and HLA-A2. Nature, 387: 630-634.
