Name: LUO Cheng

Gender: Male

Degree: Ph.D

Title: Professor

Organization: University of Tartu, Estonia, Tianijn University of Science and Technology

Education Experience:

Work Experience:

Rewards:

Academy of Finland 1992, CIMO, Finland 1993,  Wang Kuancheng Foundation, Hong Kong, 1999.

Research Area:

Food Science, immunology,  Biotechnology, Molecular Biology, Cell Biology, Biophysics, etc.

Publication:

Ling Liu, Jingkai Zhang, Meiling Li, Xiaohong Zhang, Jinlu Zhang, Zhenjing Li, Likui Wang, Jihui Wu, Cheng Luo, Inhibition of HepG2 cell proliferation by ursolic acid and polysaccharides via downregulation of cyclooxygenase-2, Molecular Medicine Reports Accepted, 2013.

1,  Junhua Wu, Mengxian Li, Ling Liu, Qi An, Jinlu Zhang, Jingkai Zhang, Meiling Li, Weigang Duan, Dequan Liu, Zhenjing Li, Cheng Luo. Nitric Oxide and Interleukins are Involved in Cell Proliferation of RAW264.7 Macrophages Activated by Viili Exopolysacchrides.Inflammation, 2013, Vol 36, No. 4, pp 954-961.

2， Lu X, Liu W, Wu J, Li M, Wang J, Wu J, Luo C*. A polysaccharide fraction of adlay seed (Coix lachryma-jobi L.) induces apoptosis in human non-small cell lung cancer A549 cells. Biochem Biophys Res Commun. 2013, vol. 430 (2): 846-851.  doi: 10.1016/j.bbrc.2012.11.058.

3， Liu W, Lu X, He G, Gao X, Li M, Wu J, Li Z, Wu J, Wang J, Luo C*. Cytosolic protection against ultraviolet induced DNA damage by blueberry anthocyanins and anthocyanidins in hepatocarcinoma HepG2 cells. Biotechnol Lett. 2012 Nov 29. https://www.ncbi.nlm.nih.gov/pubmed/23192380

4,  Gao X, Liu Q，Zhao Y, Li Z, Zhou, Jiang K, Luo C*. 2012 Influences of gold and silver nanoparticles in loop-mediated isothermal amplification (LAMP) reactions, Journal of Experimental nanosciences doi/full/10.1080/17458080.2012.743684

5, Liu L. Wu JH. Zhang JL, Li ZJ，Wang CL, Chen MH,         Wang YR, Sun YX, Wang LK,  Luo C*.A compatibility assay of ursolic acid and foodborne microbial exopolysaccharides by antioxidant power and anti-proliferative properties in hepatocarcinoma cells. J. Food, Agriculture, Environment 2012, 10 (2): 111-114. SCI

6,  17，Luo, C.*; Urgard, E.; Vooder, T.; Metspalu, A. (2011). The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging. Medical Hypotheses, 77(2), 174 - 178 .

7． Urgard, Egon; Vooder, Tõnu; Võsa, Urmo; Välk, Kristjan; Liu, Mingming; Luo, Cheng; Hoti, Fabian; Roosipuu, Retlav; Annilo, Tarmo; Laine, Jukka; . Frenz, Christopher M; Zhang, Liqing; Metspalu, Andres (2011). Metagenes associated with survival in NSCLC. Cancer Informatics, 10, 175 - 183.

8.  Sun WH, Chen  GS, Ou XL, Yang Ye, Luo C,  Zhang Y,  Shao Y,   Xu HC, Xiao B,  Xue YP,  Zhou SM, Zhao QS, Ding GX, 2009 Inhibition of cyclooxygenase-2 and activation of peroxisome proliferator-activated receptor-γ synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells. 275,247-255.

9，Sun WH, Su H,Zhu F, Chen GS, Luo C, Zhao Q, Zhang Y. Shao Y, Sun J, Zhou SM, Ding GX, Cheng YL, 2008, Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, but independently inhibits the proliferation of human gastric cancer cells in vitro, Cancer Letter, Vol. 263, p. 302-311.

10，Luo C*, Wang K, Liu DQ, Li Y, Zhao Q, The Functional Roles of Lipid Rafts in T-Cell Activation, Immune Diseases and HIV Infection and Prevention. Cell and Immunology, Vol.5 No.1, p.1-7, 2008.

11，Luo C*, Peng Y, Santti R, He ML  and Lin MC. COX-1 and 2 expressions in sex-related organs of neonatally estrogen treated rats and in activated and non-activated macrophage RAW264.7cells with phytoestrogen, Endorine,Vol.29, No.1, p.161-167,2006.

12， Luo C*, He ML and Bohlin L. 2005, Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial. Acta Pharmacologica Sinica, Acta Pharmacol Sin. 26 (8): 926-933.

13， Luo C*, Simell O, Kung HF and He ML, The simultaneous and spontaneous coexpression of insulin and COX-2 in beta cells, and the infiltration of leukocytes in inflamed islets in adoptive transferred NOD/SCID mice. European Journals of Inflammation,Vol.3, No.2, pp55-61, 2005,

14，  Luo C* and Laaja P, 2004, Inhibitors of JAKs/STATs and the kinases, a possible new cluster of drugs, Drug Discovery Today, Vol.9, No.6, pp268-275.

15，. Luo C*, Kallajoki M, Makinen M, Teros T, Ylinen L, Simell O, 2002, Distribution and contribution of cyclooxygenase(COX)-2 for diabetogenesis in NOD mouse model, Cell &Tissue Research,Vol.310, p169-175.

16， Luo C*, Laine JVO, Ylinen L, Teros T, Makinen M, Ristimaki A, and Simell O, 2002, Expression of cyclooxygenase-2 in intestinal goblet cells of prediabeticnon-obese diabetic mice, Acta Physiologica Scandinavica, 174 (3): 265-274.

17，Luo C*, Strauss L, Streng T, Ristimaki A ,Santti R. Constant Expression of cyclooxygenase-2 gene in the lower urinary tract and prostate of the mail rats treated with estrogen, Zeitschriftfur Naturforschung, 56C:455-463, 2001.

18，Wu.X, Sallinen K, Antila L, Makinen M, Luo C, Pallanen P, Erkkola R. 2000, Expression of insulin-receptor substrate-1 and -2 in ovaries from woman with insulin resistance and controls. Fertinity and Sterility, Vol.74, No.3: 564-572.

19，Tingtao Chen, Qianglai Tan, Mengjuan Wang, Shunqiang Xiong, Shuying Jiang, Qinglong Wu, Shengjie Li, Cheng Luo, and Hua Wei. Identification of bacterial strains in viili by molecular taxonomy and their synergistic effects on milk curd and exopolysaccharides production. African Journal of Biotechnology.

20，Luo C and Laaja P, 2004, Inhibitors of JAKs/STATs and the kinases, a possible new cluster of drugs, Drug Discovery Today, Vol. 9, No. 6, pp268-275.

21,  Luo, C.; Kleczkowski, L.A. (1999). Expression of barley ADP-glucose pyrophosphorylase in Escherichia coli: Processing and regulatory considerations . Phytochemistry, 50(2), 209 - 214.

22,  Kleczkowski, L.A.; Sokolov, L.N.; Luo, C.; Villand, P. (1999). Molecular cloning and spatial expression of an ApL1 cDNA for the large subunit of ADP-glucose pyrophosphorylase from Arabidopsis thaliana. Zeitschrift Fur Naturforschung C-a Journal of Biosciences, 54(5-6), 353 - 358.

23,  Witte, A.; Baranyi, U.; Klein, R.; Sulzner, M.; Luo, C.; Wanner, G.; Kruger, D.H.; Lubitz, W. (1997). Characterization of Natronobacterium magadii phage Phi Ch1, a unique archaeal phage containing DNA and RNA. Molecular Microbiology, 23(3), 603 - 616.

24,   Eimert, K.; Luo, C.; Dejardin, A.; Villand, P.; Thorbjornsen, T.; Kleczkowski, L.A. (1997). Molecular cloning and expression of the large subunit of ADP-glucose pyrosphosphorylase from barley (Hordeum vulgare) leaves. Gene, 189(1), 79 - 82.

25,  Luo, C.; Dejardin, A.; Villand, P.; Doan, D.; Kleczkowski, L.A. (1997). Differential processing of homologues of the small subunit of ADP-glucose pyrphosphorylase from barley(Hordeum vulgare) tissues. Zeitschrift Fur Naturforschung C-a Journal of Biosciences, 52(11-12), 807 - 811.

26,   Hantula, J.; Koivula, T. T.; Luo, C.; Bamford, D. H. (1996). Bacterial diversity at surface water in three locations within the Baltic sea as revealed by culture-dependent molecular           techniques. Journal of Basic Microbiology, 36(3), 163 - 176.

27,        Bamford, J.K.H.; Luo, C.; Juuti, J.T.; Olkkonen, V.M.; Bamford, D.H. (1993). Topology of the major capsid protein P3 of bacteriophage PRD1: Analysis using monoclonal antibodies and C-terminally truncated proteins. Virology, 197(2), 652 - 658.

28,  Caldentey, J.; Luo, C.; Bamford, D.H. (1993). Dissociation of the lipid- containing bacteriophage PRD1, effects of heat, pH, and sodium dedecyl sulphate. Virology, 194(2), 557 - 563.

29,  Luo, C.; Hantula, J.; Tichelaar, W.; Bamford, D.H. (1993). Bacteriophage PRD1 protein: crosslinking and scanning transmission electron microscopy analysis. Virology, 194(2), 570 - 575.

30,  Luo, C.; Butcher, S.; Bamford, DH. (1993). Isolation of a phospholipid-free protein shell of bacteriophage PRD1, an E.coli virus with an internal membrane. Virology, 194(2), 564 - 569.