Name:LIU Hu-Wei
Gender: Male
Degree: Ph.D
Title: Professor
Organization: Peking University
Education Experience:
B.S., Beijing Institute of Technology, 1982.7
M.S., Beijing Institute of Technology, 1987.7
Ph.D., Beijing Institute of Technology, 1990.7.
Work Experience:
Lecturer, Peking University, 1990.8- 93.8
Associate Professor, Peking University, 1993.8- 2001.8
Professor, Peking University, 2001.8-presnet
Exchange Scholar, University of Helsinki, Finland, 1995.9-96.7
Visiting Scientist, Purdue University, and BioAnalytical Systems, Inc. USA, 1996.7-97.3
Rewards:
CAIA award, 2009
CAIA award, 2001
Research Area:
Bioseparation and detection, including chromatographic and electromigration techniques as well as their online coupling to mass spectrometry; pharmaceutical analysis; bioanalysis and clinical analysis.
Publication:
1. Li-Ping Li, Tao Zheng, Lin-Nan Xu, Ze Li, Ling-Dong Sun, Zong-Xiu Nie, Yu Bai* and Hu-Wei Liu*, SnO2–ZnSn(OH)6: a novel binary affinity probe for global phosphopeptide detection, Chem. Commun., 2013, 49, 1762-1764
2. Cuilan Chang, Gege Xu, Yu Bai*, Chengsen Zhang, Xianjiang Li, Min Li, Yi Liu and Huwei Liu*, Online Coupling of Capillary Electrophoresis with Direct Analysis in Real Time Mass Spectrometry, Anal. Chem., 2013, 85 (1): 170–176
3. Jialing Zhang, Zhigui Zhou, Jianwang Yang, Wei Zhang, Yu Bai * and Huwei Liu, Thin Layer Chromatography/Plasma Assisted Multi-wavelength Laser Desorption Ionization Mass Spectrometry for Facile Separationmand Selective Identification of Low Molecular Weight Compounds, Anal. Chem. 2012, 84(3): 1496–1503,DOI: 10.1021/ac202732y
4. Zhigui Zhou, Youyou Yang, Jialing Zhang, Zhenxiang Zhang, Yu Bai, Yiping Liao and Huwei Liu*, A Novel Membrane-Based Enzyme Micro-reactor Coupled Online with LC/QTOF MS for Protein Analysis, Anal. Bioanal. Chem., 2012, 403(1): 239-246
5. Jialing Zhang, Ze Li, Chengsen Zhang, Baosheng Feng, Zhigui Zhou, Yu Bai and Huwei Liu*, Graphite Coated Paper as Substrate for High Sensitive Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry, Anal Chem., 2012, 84 (7): 3296–3301
6. Yehua Han, Zhigui Zhou, Hongliang Wu, Honggang Nie, Rong Lei, Yu Bai and Huwei Liu*, Determination of jasmonic acid epimers and their epimerization study by chiral liquid chromatography-mass spectrometry, J. Chromatogr. A, 2012, 1235: 125-137
7. Zhigui Zhou, Jialing Zhang, Jiawei Xing, Yu Bai and Huwei Liu*, Membrane-based Continuous Remover of Trifluoroacetic Acid (TFA) in Mobile Phase for LC-ESI-MS Analysis of Proteins, J. Am. Soc. Mass Spectrom., 2012, 23(7): 1289-1292
8. Cuilan Chang, Xin Wang, Yu Bai and Huwei Liu*, The applications of nanomaterials in enantioseparation and related techniques, Trend in Anal. Chem., TrAC, 2012, 39: 195–206
9. Cuilan Chang, Zhigui Zhou, Youyou Yang, Yehua Han, Yu Bai and Huwei liu*, Normal phase HPLC coupled with DART-MS for the chiral analysis of 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol and jasmonic acid, Electrophoresis, 2012, 33(22): 3387–3393
10. Min Li, Zhigui Zhou, Honggang Nie, Yu Bai and Huwei Liu*, Recent advances of chromatography and mass spectrometry in lipidomics, Anal. Bioanal. Chem., 2011, 399: 243–249
11. Yi Liu, Xiaofang Fu, Yu Bai, Maolin Zhai, Yiping Liao, Jie Liao and Huwei Liu*, Improvement of reproducibility and sensitivity of CE by using the capillary coated dynamically with carboxymethyl chitosan, Anal. Bioanal. Chem., 2011, 399: 2821–2829
12. Zhigui Zhou, Jialing Zhang, Wei Zhang, Yu Bai* and Huwei Liu, Rapid screening for synthetic antidiabetic drug adulteration in herbal dietary supplements using direct analysis in real time mass spectrometry, Analyst, 2011, 136 (12): 2613 – 2618
13. Xiaofang Fu, Yi Liu, Wei Li, Yu Bai, Yiping Liao and Huwei Liu*, Determination of dissociation constants of aristolochic acid I and II by capillary electrophoresis with carboxymethyl chitosan-coated capillary, Talanta, 2011, 85(15): 813–815
14. Youyou Yang, Cong Yu, Meng Zhou, Ning Li, Jie Liao, Yu Bai and Huwei Liu*, Research on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to the enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in vitro in human bronchial epithelial cells using chiral capillary electrophoresis, J. Chromatogr. A, 2011, 1218: 6505–6510
15. Yehua Han, Yu Bai, Yiling Xiao, Fuyou Du, Yuan Liang, Zhijing Tan, Meiping Zhao and Huwei Liu*, Simultaneous discrimination of jasmonic acid stereoisomers in wounded tobacco leaves by CE-QTOF-MS employing the partial filling technique, Electrophoresis, 2011, 32(19): 2693-2699
16. Yu Bai, Fuyou Du, Youyou Yang, Yu Bai and Huwei Liu*, In-capillary non-covalent labeling and determination of tomato systemin with quantum dots in capillary electrophoresis with laser-induced fluorescence detection, J. Sep. Sci., 2011, 34:2893–2900
17. Caiqiao Xiong, Xiaoyu Zhou, Rui Chen, Yiming Zhang, Wen-Ping Peng, Zongxiu Nie*, Huan-Cheng Chang, Huwei Liu and Yi Chen, Characterization of Column Packing Materials in High-Performance Liquid Chromatography by Charge-Detection Quadrupole Ion Trap Mass Spectrometry, Anal. Chem., 2011, 83 (13): 5400–5406
18. Yehua Han, Pavel Levkin, Irene Abarientos, Huwei Liu, Frantisek Svec and Jean Frechet, Monolithic Superhydrophobic Polymer Layer with Photopatterned Virtual Channel for the Separation of Peptides Using Two-Dimensional Thin Layer Chromatography- Desorption Electrospray Ionization Mass Spectrometry, Anal. Chem., 2010, 82: 2520–2528
19. Honggang Nie, Ranran Liu, Youyou Yang, Yu Bai, Yafeng Guan, Daqing Qian , Tao Wang and Huwei Liu*, Lipid profi ling of rat peritoneal surface layers by online, normal- and reverse-phase 2D LC QToF-MS, J. Lip. Res., 2010, 51: 2833-2844
20. Youyou Yang, Honggang Nie, Chenchen Li, Yu Bai, Ning Li, Jie Liao and Huwei Liu*,On-line concentration and determination of tobacco-specific N-nitrosamines by cation-selective exhaustive injection-sweeping-micellar electrokinetic chromatography,Talanta, 2010, 82: 1797–1801
21. Fuyou Du, Yu Bai, Yu Bai and Huwei Liu*, Quantitative Detection of Trace Systemins in Solanaceous Plants by Immunoaffinity Purification combined with LC/ESI QTOF MS, Anal. Chem., 2010, 82: 9374–9383
22. Zhengxiang Zhang, Bo Yan, Kelin Liu, Yiping Liao and Huwei Liu*, CE-MS analysis of heroin and its basic impurities using charged polymer-protected gold nanoparticles-coated capillary, Electrophoresis, 2009, 30: 379–387
23. Yi Liu, Xiaofang Fu, Chao Ma, Jiasheng Zhong and Huwei Liu*, Chiral separation of Raltitrexed by cyclodextrin-modified micellar electrokinetic chromatography, Anal. Bioanal. Chem., 2009, 393: 321–326
24. Nannan Pang, Zhengxiang Zhang and Huwei Liu*, Enantioseparation of zolmitriptan and determination of binding constants and thermodynamic parameters by CD-modified CZE, Anal. Bioanal. Chem., 393 (2009) 313--320
25. Yu Zhou, Hailin Shen, Tie Yi, Dawei Wen, Nannan Pang, Jie Liao and Huwei Liu*,Synergistic Design of Electric Field and Membrane in Facilitating Continuous Adsorption for Cleanup and Enrichment of Proteins in Direct ESI-MS Analysis,Anal. Chem., 2008, 80: 8920–8929
26. Zhengxiang Zhang, Bo Yan, Yiping Liao and Huwei Liu*,Nanoparticles: is it promising in capillary electrophoresis? Anal. Bioanal. Chem., 2008, 391: 925-927
27. Zhengxiang Zhang, Bo Yan, Kelin Liu, Yiping Liao and Huwei Liu*,Separation and fragmentation study of heroin and its basic impurities by reversed-phase liquid chromatography coupled to tandem mass spectrometry, Rapid Commun. Mass Spectrom., 2008, 22: 2851-2862.
28. Youyou Yang and Huwei Liu, Separation and Determination of Tobacco-Specific N-Nitrosamines, in Fernanda López Marcos and Cristofer Ramírez Ortiz (Ed), Tobacco: Production, Uses and Health Implications, Nova Science Publishers, Inc. 2012, New York
29. Yi Liu, Yu Bai, and Huwei Liu, Analytical Methodologies of Chitosan in Functional Foods, in Leo M.L. Nollet and Fidel Toldra (Ed), Handbook of Analysis of Active Compounds in Functional Foods, CRC Press, Boca Raton, FL, USA, 2012, p513-544