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| 重庆市巴南区市售鸡蛋中残留兽药现状调查及膳食暴露风险评估 |
| Survey on the current status of residue of veterinary drugs in eggs on sale in Banan district, Chongqing and assessment of dietaryposure risk |
| 投稿时间：2025-02-12 修订日期：2025-06-11 |
| DOI： |
| 中文关键词: 鸡蛋 兽药残留 膳食暴露评估 健康风险 |
| 英文关键词:Eggs Veterinary drug residues Dietary exposure assessment Health risk |
| 基金项目:重庆市巴南区2022年度区级科技项目（KY202208185571003） |
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| 中文摘要: |
| 目的 了解重庆市巴南区市售鸡蛋中兽药残留现状，评估居民膳食摄入残留兽药导致的健康风险。方法 于2024年随机抽取重庆市巴南区10个镇街的集贸市场和超市售卖的鸡蛋共208份，采用液相色谱-串联质谱法(LC-MS/MS)检测15种兽药残留含量，通过点评估法计算每日估计暴露量和危害商，评估膳食暴露风险。结果 208份市售鸡蛋样本中兽药残留检出率8.65% (18/208)，检出率最高为多西环素3.37% (7/208)；不合格率0.96% (2/208)，不合格样本主要来源于集贸市场售卖的散装无品牌鸡蛋。膳食暴露评估显示，兽药残留的每日估计暴露量范围为0.00013～0.03450μg/（kg·bw·d），危害商范围为0.00000～0.00872，远低于安全阈值，提示摄入市售鸡蛋中残留兽药所引起的人体健康危害风险较低。结论 重庆市巴南区市售鸡蛋存在兽药残留现象，但残留量总体可控，健康风险较低。需重点关注散装和无品牌鸡蛋的监管，并完善兽药使用规范及残留限量标准。 |
| 英文摘要: |
| ABSTRACT：Objective To investigate the current status of veterinary drug residues in eggs sold in Banan District, Chongqing, and assess the health risk of residues’ dietary intake residues. Methods In 2024, a total of 208 egg samples were randomly collected from markets and supermarkets in 10 towns and streets of Banan District. The residues of 15 veterinary drugs were detected using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The point assessment method was employed to calculate the daily estimated exposure and hazard quotient for dietary exposure risk assessment.Results The detection rate of Veterinary drug residues in 208 samples of market eggs was 8.65% (18/208), with doxycycline showing the highest detection rate at 3.37% (7/208). The unqualified rate was 0.96% (2/208), with the unqualified samples mainly coming from unbranded bulk eggs sold in markets. The dietary exposure assessment revealed that the daily estimated exposure of veterinary drug residues ranged from 0.00013 to 0.03450 μg/(kg·bw·d), and the hazard quotient ranged from 0.00000 to 0.00872,significantly below the safety threshold. This indicates a low health risk associated with the intake of veterinary drug residues in eggs sold in the market. Conclusion Veterinary drug residues were detected in eggs sold in Banan District, Chongqing, but the residue is generally controllable and the health risk low. Special attention should be given to bulk and unbranded eggs,and standards for veterinary drug use and residue limits should be further refined. |
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