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| 哈尔滨地区水稻真菌产毒力及市售大米真菌毒素污染风险评估 |
| Toxigenic capacity of rice fungi in Harbin area and risk assessment of fungal toxin contamination in commercially available rice |
| 投稿时间：2025-02-08 修订日期：2025-06-11 |
| DOI： |
| 中文关键词: 哈尔滨 水稻 真菌 毒素 风险评估 |
| 英文关键词:Harbin rice fungi toxins risk assessment |
| 基金项目:安顺市科技计划项目(安市科农重﹝2023﹞01号；安市科平(2023)07号),哈尔滨市优秀学科带头人基金 (2019RAXYJ085) |
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| 中文摘要: |
| 目的 探明哈尔滨市地产大米真菌毒素污染情况并对其进行风险评估,从而为稻米质量安全监管提供基础数据。方法 采用液相色谱串联质谱联用法检测检测市售地产稻花香2号大米黄曲霉毒素B1(AFB1)和赭曲霉毒素A(OTA)的含量。通过Monte Carlo模拟和Bootstrap抽样技术,采用非参数概率评估方法和点评估方法,评估了哈尔滨地区不同人群通过食用大米对黄曲霉毒素B1和赭曲霉毒素A的膳食暴露风险。结果 建立了AFB1和OTA的膳食暴露模型。研究发现无论是AFB1,还是OTA,儿童都是高风险人群,尤其是儿童中的高消费人群,通过食用大米导致肝癌的潜在风险较大。结论 哈尔滨地区居民食用大米导致AFB1和OTA暴露的健康风险总体较低,但儿童高消费人群潜在健康风险较大,需要引起高度注意,其它人群无明显的健康风险。 |
| 英文摘要: |
| Objective Investigate and assess the contamination of fungal toxins in locally produced rice in Harbin region, and conduct a risk assessment. Thereby provide basic data for the supervision of rice quality and safety. Methods The content of aflatoxin B1 (AFB1) and ochratoxin A (OTA) in commercially available locally produced Daohuaxiang No. 2 rice was detected using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Monte Carlo simulation and Bootstrap sampling techniques were applied, non-parametric probabilistic assessment methods and point assessment methods were employed to evaluate the dietary exposure risk of different populations in Harbin to AFB1 and OTA through the consumption of rice. Results A dietary exposure model for AFB1 and OTA has been established. This study found that both AFB1 and OTA pose a high risk to children, especially those with high consumption levels, who have a greater potential risk of developing liver cancer through rice consumption. Conclusion The overall health risk of AFB1 and OTA exposure through rice consumption among residents in Harbin is relatively low. However, there is a significant potential health risk for high-consuming children, which requires much more attention. Apparent health risks were not found for other populations. |
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