蒲公英多糖提纯、结构特征、生物活性、构效关系与应用研究进展

Research progress in the purification, structural characterization, bioactivity, conformational relationship and application of Dandelion polysaccharides

中文关键词:  蒲公英多糖,提取纯化,结构特征,生物活性,构效关系

英文关键词:Dandelion polysaccharide  extraction and purification  structural characterization  bioactivity  conformational relationship

中文摘要:

      蒲公英是我国药食同源植物, 来源广泛, 兼具丰富的营养和药理价值。蒲公英多糖是其中重要的功能活性成分之一, 国内外研究发现其具有多种生物活性。本文系统回顾了蒲公英多糖的提取纯化方法, 解析了蒲公英多糖的初级结构特征, 如分子量、单糖组成和化学结构, 归纳分析了蒲公英多糖的抗氧化、抑菌、免疫调节、降血糖、抗炎、抗肿瘤等生物活性及相关作用机制, 探讨了蒲公英多糖结构与其生物活性之间的构效关系, 旨在为蒲公英多糖在食品和医药等方面的深度开发和应用提供重要的理论参考依据。

英文摘要:

      Dandelion is a medicinal and food plant in China, with a wide range of sources and rich nutritional and pharmacological values. Dandelion polysaccharide is one of the important functional active ingredients, and domestic and international studies have found that it has a variety of biological activities. This paper systematically reviewed the extraction and purification methods of Dandelion polysaccharides, analyzed the primary structural features of Dandelion polysaccharides, such as molecular weight, monosaccharide composition and chemical structure, and summarized and analyzed the biological activities and related mechanisms of Dandelion polysaccharides, such as antioxidant, anti-bacterial, immune regulation, hypoglycemia, anti-inflammatory and anti-tumor, etc., and explored the conformational relationship between the structure of Dandelion polysaccharides and its biological activities, which is aimed to provide the basis for the deep development of Dandelion polysaccharides in food and medicine. This study aims to provide important theoretical references for the development and application of Dandelion polysaccharides in food and medicine.