基于巯基化合物检测和去除展青霉素的研究进展

Research Progress on the Detection and Removal of PAT Based on Thiol Compounds

中文关键词:  巯基化合物  展青霉素  检测  吸附  分离

英文关键词:Thiol compounds  patulin  detection  adsorption  separation

中文摘要:

      展青霉素是一种由青霉属和曲霉属等真菌产生的次级代谢产物，广泛存在于水果及其制品中。因其具有多种毒性，对食品安全构成严重威胁。巯基化合物的硫醇基团具有化学活性，在展青霉素的检测和去除中表现出显著的作用。巯基化合物通过迈克尔加成反应与展青霉素的丙内酯环特异性结合，显著降低展青霉素的毒性和含量。此外，功能化的巯基材料如巯基修饰的纳米颗粒和气凝胶等，展现了优异的吸附性能和分离效率，为食品安全提供了高效、经济且环保的解决方案。本文综述了巯基化合物在展青霉素检测和去除等方面的研究进展及其作用机制，以期为未来的食品安全研究与应用提供理论参考。

英文摘要:

      Patulin (PAT) is a secondary metabolite produced by fungi such as Penicillium and Aspergillus species, widely present in fruits and their products. Due to its multiple toxicities, it poses a severe threat to food safety. The thiol group in sulfhydryl compounds exhibits chemical reactivity and demonstrates a significant role in the detection and removal of PAT. Through Michael addition reactions, thiol compounds specifically bind to the β-lactone ring of PAT, substantially reducing its toxicity and concentration. Furthermore, functionalized thiol materials, such as thiol-modified nanoparticles and aerogels, demonstrate excellent adsorption performance and separation efficiency, providing efficient, economical, and environmentally friendly solutions for ensuring food safety. This paper reviews the research progress and underlying mechanisms of thiol compounds in the detection and removal of PAT, aiming to provide theoretical references for future research and applications in food safety.