电感耦合等离子体质谱法测定食品中总砷

Determination of total arsenic in food by inductively coupled plasma mass spectrometry

中文关键词:  改进  电感耦合等离子体质谱 増敏剂  总砷 食品

英文关键词:inductively coupled plasma mass spectrometry  sensitizer  total arsenic

中文摘要:

      目的 建立电感耦合等离子体质谱法测定食品中总砷。方法 称取0.3 g生物成分标准物质大米和菠菜, 采用微波消解仪进行消解, 然后利用碰撞模式减少质谱干扰, 用内标校正非质谱干扰, 选择乙酸、异丙醇、甲醇、乙醇作为增敏剂, 并调节和优化添加的增敏剂浓度, 用电感耦合等离子体质谱法测定砷的响应值。结果 在异丙醇含量为6%时, 砷元素响应值最高。用建立的方法对食品标准物质及实际样品进行分析, 标准物质测定值均在其认定值及不确定度范围内, 相对误差小于2.0%, 总砷的检出限为0.0016 mg/kg。结论 此方法操作简便、精密度好、准确度高, 检出限低, 可以作为各类食品样品中总砷含量测试方法。

英文摘要:

      Objective To establish a method for determination of total arsenic in food by inductively coupled plasma mass spectrometry. Methods The 0.3 g of the biological component standard substances, namely rice and spinach, were weighed and digested using a microwave digestion instrument. Then, the collision mode was adopted to reduce the interference of mass spectrometry. The non-mass spectrometry interference was corrected by the internal standard. Acetic acid, isopropanol, methanol and ethanol were selected as sensitizers, and the concentration of the added sensitizers was adjusted and optimized. The response value of arsenic was determined by inductively coupled plasma mass spectrometry. Results The highest arsenic response value was observed at 6% isopropanol content. The established method was applied to analyze certified reference materials and real food samples. The measured values of certified reference materials all fell within their certified values and uncertainty ranges, with relative errors below 2.0%. The limit of detection for total arsenic was 0.0016 mg/kg. Conclusion This method demonstrates straightforward operation, good precision, high accuracy, and a low limit of detection, making it suitable as a reliable analytical approach for determining total arsenic content in various food samples.