联苯肼酯和乙螨唑在豇豆上的消解动态及膳食暴露风险评估

Dissipation dynamics and dietary exposure risk assessments of bifenazate and etoxazole in Vigna unguiculata

中文关键词:  豇豆  复配使用  农药残留  短期膳食暴露  长期膳食暴露  

英文关键词:Vigna unguiculata  mixture application  pesticide residue  short-term dietary exposure  long-term dietary exposure

中文摘要:

      目的 评估联苯肼酯和乙螨唑复配使用在豇豆上的消解动态及对不同人群的膳食暴露风险。方法 采用液相色谱-串联质谱法对全国8个地区露地条件下豇豆上联苯肼酯(联苯肼酯和联苯肼酯-二氮烯的总和)和乙螨唑残留进行检测分析。根据检测结果和我国不同人群的膳食消费量与体重数据进行了膳食暴露风险评估。结果 联苯肼酯在山东、安徽、湖南和广西豇豆上的消解动态过程均不符合一级动力学方程。乙螨唑在山东、安徽和广西豇豆上的消解动态过程均符合一级动力学方程, 半衰期为1.93~2.54 d; 乙螨唑在湖南豇豆上的消解动态不符合一级动力学方程。在豇豆上施用45%联苯肼酯·乙螨唑悬浮剂, 制剂用量为8 mL/亩, 喷雾施药1次, 在10 d采收间隔下, 联苯肼酯和乙螨唑在豇豆上的最终残留量分别为<0.0100 mg/kg和<0.0020~0.0042 mg/kg。这两种农药对各人群的长期膳食暴露风险贡献值均远低于100%, 表示没有不可接受的风险。结论 45%联苯肼酯·乙螨唑悬浮剂, 在豇豆上防治红蜘蛛, 制剂用药量8 mL/亩剂量, 喷雾施药1次, 安全间隔期推荐为10 d。

英文摘要:

      Objective To evaluate the degradation dynamics of the combined use of bifenazate and etoxazole on Vigna unguiculata and assess the dietary exposure risks for different population groups. Methods Bifenazate (sum of bifenazate and bifenazate-diazene) in samples of Vigna unguiculata collected from eight regions of China were detected by liquid chromatography-tandem mass spectrometry. Dietary exposure risk assessment was conducted based on the test results , dietary consumption data and body weight data of different population groups in China. Results The dissipation behaviors of bifenazate in Vigna unguiculata from Shandong, Anhui, Hunan and Guangxi all did not follow first-order kinetics. The dissipation behaviors of etoxazole in Vigna unguiculata from Shandong, Anhui, Hunan, and Guangxi followed first-order kinetics, and their half-lives were 1.93–2.54 d. Using a suspension concentrate containing 45% bifenazate and etoxazole with 8 mL formulation per mu (Chinese acre) to control red mites on Vigna unguiculata, spraying once, at the harvest interval of 10 d, terminal concentrations of bifenazate and etoxazole in Vigna unguiculata were <0.0100 mg/kg and <0.0020–0.0042 mg/kg, respectively. The contribution rate of the long-term dietary exposure risk of these 2 kinds of pesticides were all lower than 100% for different population groups, indicating that there was no unacceptable risk. Conclusion 45% bifenazate·etoxazole suspension concentrate is applied at a dosage of 8 mL per mu for controlling spider mites on Vigna unguiculata, with one spray application and a recommended pre-harvest interval of 10 days.