气相色谱-质谱法测定食品接触材料中9,9-双(甲氧基甲基)芴的迁移量

Determination of 9,9-bis(methoxymethyl)fluorene migration in food contact materials by gas chromatography-mass spectrometry

中文关键词:  9,9-双(甲氧基甲基)芴  气相色谱-质谱法  食品接触材料  迁移量

英文关键词:9,9-bis(methoxymethyl)fluorene  gas chromatography-mass spectrometry  food contact materials  migration

中文摘要:

      目的 建立气相色谱-质谱法测定塑料类食品接触材料及制品中9,9-双(甲氧基甲基)芴迁移量的方法。方法 水基食品模拟物经正己烷萃取后进样, 化学替代溶剂(95%乙醇和异辛烷)直接进样, 橄榄油模拟物用乙腈进行萃取后进样, 使用气相色谱-质谱仪分析, 采用外标法定量。结果 建立了塑料类食品接触材料中9,9-双(甲氧基甲基)芴迁移量的测定方法, 检出限为0.01 mg/kg或mg/L, 定量限为0.03 mg/kg或mg/L, 加标回收率为80.0%~110.0%, 相对标准偏差为1.2%~6.0% (n=6)。运用该方法对10款聚丙烯(polypropylene, PP)食品接触材料的实际样品进行测定, 检出率为10%, 检出浓度为0.12 mg/kg。结论 该方法灵敏, 回收率高和准确度高, 检出限能够满足法规判定要求, 可用于PP塑料类食品接触材料中9,9-双(甲氧基甲基)芴迁移量的实际检验工作。

英文摘要:

      Objective To establish a method for the determination of the migration of 9,9-bis(methoxymethyl)fluorene in plastic food contact materials and articles by gas chromatography-mass spectrometry. Methods The water-based food simulants were extracted by n-hexane, and the chemical alternative solvents (95% ethanol and isooctane) were directly injected, and the olive oil simulants were extracted with acetonitrile and then injected, and the samples were analyzed by gas chromatography-tandem mass spectrometry and quantified by external standard method. Results A method for the determination of 9,9-bis(methoxymethyl)fluorene in plastic food contact materials was established. The limit of detection was 0.01 mg/kg or mg/L, the limit of quantification was 0.03 mg/kg or mg/L, the recovery rates were 80.0%–110.0%, and the relative standard deviations were 1.2%–6.0% (n=6). The actual samples of 10 kinds of polypropylene (PP) food contact materials were determined by this method, and the detection rate was 10%, and the detection concentration was 0.12 mg/kg. Conclusion The method is sensitive, has high recovery and accuracy, and the limit of detection can meet the requirements of regulations, and can be used for the practical testing of the migration of 9,9-bis(methoxymethyl)fluorene in polypropylene (PP) food contact materials.