婴儿配方食品中克罗诺杆菌属检测技术研究进展

Research progress on detection technology of Cronobacter spp. in infant formula food

中文关键词:  婴儿配方食品  克罗诺杆菌属  检测技术

英文关键词:infant formula food  Cronobacter spp.  detection technology

中文摘要:

      克罗诺杆菌属是一类广泛存在于自然环境中的食源性条件致病菌, 该菌属特点为可耐受干燥和高渗透压, 可在干燥的奶粉中长期存活, 婴儿配方食品可能在生产过程、运输储运过程及冲调过程中被污染, 感染后可能导致婴儿菌血症、脑膜炎、坏死性小肠结肠炎, 并可能引起严重的神经系统后遗症, 甚至死亡。因此建立高效、准确的克罗诺杆菌属检测方法是预防和控制该类疾病的关键, 对于保障婴儿配方食品的质量与安全有着重要意义。目前克罗诺杆菌属的检测方法主要有传统分离培养法、分子生物学方法、免疫学方法等, 近年来许多研究在此基础上进行了不同程度的改进优化。本文对目前针对克罗诺杆菌属的各种检测方法的原理及优缺点进行了系统综述, 旨在为该菌属检测技术的深入研究及国家与行业检测标准的优化更新提供参考。

英文摘要:

      Cronobacter spp. is a group of foodborne opportunistic pathogens widely present in the natural environment, characterized by their ability to tolerate desiccation and high osmolarity, enabling them to survive for extended periods in dried milk powder. Infant formula products may become contaminated during production, transportation, storage, and even during the reconstitution process. Infection with Cronobacter spp. can lead to severe illnesses such as bacteremia, meningitis, necrotizing enterocolitis in infants, and may result in serious neurological sequelae or even death. Therefore, establishing efficient and accurate detection methods for Cronobacter spp. is crucial for preventing and controlling these diseases, and holds significant importance in ensuring the quality and safety of infant formula products. Currently, the main detection methods for Cronobacter spp. include traditional culture-based methods, molecular biology methods, and immunological methods, with numerous studies in recent years reporting various degrees of improvement and optimization based on these methods. This article systematically reviewed the principles, advantages, and disadvantages of the various detection methods currently available for Cronobacter spp., aiming to provide a reference for further research in this field and for the optimization and updating of national standards and industry standards.