益生菌清除食源性致病菌生物膜研究进展

Research progress on the removal of foodborne pathogen biofilms by probiotics

中文关键词:  食源性致病菌  生物膜  益生菌  群体感应系统

英文关键词:foodborne pathogens  biofilm  probiotics  quorum sensing system

中文摘要:

      食源性致病菌的生物膜成为引发食源性疾病和食物中毒的关键因素, 也是导致食品工厂持续污染的重要原因, 其对常规的物理、化学杀菌手段具有较强的抵抗能力, 因此, 开发有效的生物膜清除方法至关重要。本文围绕食源性致病菌生物膜的控制与清除展开, 简要介绍了新型的物理、化学和生物学方法在生物膜清除中的应用与优缺点, 重点阐述了益生菌及其代谢产物对食源性致病菌生物膜的清除机制, 包括通过生物竞争、分泌破坏生物膜的代谢产物及对群体感应系统的调节等途径抑制生物膜形成。通过讨论益生菌在食品安全方面的应用潜力以及提升益生菌的持久性和稳定性的新技术, 进一步强调了开发环保且有效的生物膜控制方法的重要性, 为提升食品生产与消费安全提供科学指导。

英文摘要:

      The biofilms of foodborne pathogens have become a key factor in causing foodborne diseases and food poisoning, as well as a significant reason for persistent contamination in food factories. These biofilms possess strong resistance to conventional physical and chemical sterilization methods, making the development of effective biofilm removal strategies crucial. This paper focused on the control and removal of biofilms from foodborne pathogens, providing a brief overview of the application, advantages, and disadvantages of novel physical, chemical, and biological methods in biofilm elimination. It emphasized the mechanisms by which probiotics and their metabolites can destroy foodborne pathogen biofilms, including inhibiting biofilm formation through biological competition, secretion of biofilm-destroying metabolites, and regulation of quorum sensing systems. By discussing the potential application of probiotics in food safety and new technologies to enhance the persistence and stability of probiotics, the paper further underscored the importance of developing eco-friendly and effective biofilm control methods, offering scientific guidance for improving the safety of food production and consumption.