2019—2023年大连市小麦、玉米及其制品中脱氧雪腐镰刀菌烯醇膳食暴露评估

Dietary exposure assessment of deoxynivalenol in Triticum, Zea mays and their processed products in Dalian City from 2019 to 2023

中文关键词:  脱氧雪腐镰刀菌烯醇  污染状况  膳食暴露  风险评估

英文关键词:deoxynivalenol  contamination  dietary exposure  risk assessment

中文摘要:

      目的 分析大连地区小麦、玉米及其制品中脱氧雪腐镰刀菌烯醇(deoxynivalenol, DON)的污染水平, 并对食用人群DON的急慢性膳食暴露风险进行评估。方法 2019—2023年在大连市内采集小麦、玉米及其制品样品287份, 应用液相色谱-串联质谱法检测DON含量, 结合2018年大连市居民膳食消费调查数据, 分别使用点估计和简单分布方法评估不同年龄组食用人群的DON急、慢性膳食暴露风险。结果 77.0%的小麦、玉米及其制品样品检出DON, 超标率为3.5%, 平均污染水平为263.62 μg/kg。急性暴露评估显示, 各年龄组人群各类小麦、玉米及其制品的DON暴露量均未超过急性参考剂量。慢性暴露评估结果显示, 3~5岁、6~10岁、11~17岁和18~64岁年龄组分别有3.85%、7.30%、1.44%和0.12%的食用人群DON暴露量超过暂定每日最大耐受摄入量。小麦及其制品是各年龄组人群DON膳食暴露的主要来源。结论 大连市小麦、玉米及其制品中DON污染较为普遍, 居民的DON膳食急性暴露风险未超出风险值, 不存在急性暴露评估风险。但部分低年龄组人群存在慢性暴露风险, 建议加强对小麦、玉米及其制品中DON的污染监测, 并关注高风险人群的健康风险。

英文摘要:

      Objective To analyze the contamination levels of deoxynivalenol (DON) in Triticum, Zea mays and their processed products in the Dalian Region and assess the acute and chronic dietary exposures of DON to the consuming population. Methods From 2019 to 2023, 287 samples of Triticum, Zea mays and their processed products were collected from Dalian. DON levels were determined using liquid chromatography-tandem mass spectrometry. Combined with the 2018 Dalian City dietary consumption survey data, acute and chronic dietary exposures of DON were assessed in different age groups using point estimation and simple distribution methods. Results DON was detected in 77.0% of the Triticum, Zea mays and their processed products, with a 3.5% over-standard rate. The average DON level was 263.62 μg/kg. Acute exposure assessment indicated that DON exposure levels in all age groups did not exceed the acute reference dose. Chronic exposure assessment revealed that 3.85%, 7.30%, 1.44%, and 0.12% of consuming populations in the 3–5, 6–10, 11–17 and 18–64 age groups, exceeded the provisional maximum tolerable daily intake, respectively. Triticum and its products were the primary dietary sources of DON exposure for all age groups.?Conclusion DON contamination is prevalent in Triticum, Zea mays and their products in Dalian City. Acute dietary exposure of DON does not exceed the threshold values. However, chronic exposure risks are shown in low age groups. Enhanced monitoring of DON contamination in Triticum, Zea mays and their processed products is recommended, along with a focus on the health risks for high-risk populations.