金纳米团簇在致病菌检测中的应用研究进展

Research progress on the application of gold nanoclusters in pathogen detection

中文关键词:  金纳米团簇  致病菌  检测

英文关键词:gold nanoclusters  pathogenic bacteria  detection

中文摘要:

      致病菌是危害食品安全和公共卫生的重要因子之一, 快速、准确检测致病菌对民生健康和社会稳定具有重要意义。近年来, 由于传统方法存在着过程烦琐、灵敏度低、检测类型单一等弊端, 研究者们通过多种手段合理地改性纳米团簇, 已开发了各类荧光传感器用于致病菌的快速、准确检测。本文重点阐述了金纳米团簇的物理化学特性, 从金纳米团簇与目标菌的不同作用方式出发, 通过直接和间接反应两个角度归纳了金纳米团簇用于致病菌检测的最新研究进展, 并对其存在的不足以及未来可能的发展方向进行讨论和展望, 旨在为金纳米团簇在致病菌快速检测领域提供参考。

英文摘要:

      Pathogenic bacteria has always been a hot topic of social concern, which is one of the important factors to harm food safety and public health. Rapid and accurate detection of pathogenic bacteria is of great significance to people’s health and social stability. In recent years, due to the drawbacks of traditional methods such as cumbersome process, low sensitivity and single detection type, researchers have developed various fluorescence sensors for rapid and accurate detection of pathogenic bacteria through reasonable modification of nanoclusters by various means. This paper focused on the physical and chemical properties of gold nanoclusters, summarized the latest research progress of gold nanoclusters for pathogenic bacteria detection from the perspective of direct and indirect reaction from the different modes of action of gold nanoclusters and target bacteria, and discussed and prospects the shortcomings and possible development directions of gold nanoclusters in the future. The aim is to provide reference for the rapid detection of pathogenic bacteria by gold nanoclusters.