重庆市禽类产品中全氟类化合物污染特征及健康风险评估

Contamination characteristics and health risk assessment of poly-and perfluoroalkyl substances in poultry products from Chongqing

中文关键词:  全氟化合物(PFASs)  禽类产品  污染特征  健康风险评估

英文关键词:poly-and perfluoroalkyl substances  poultry products  contamination characteristics  health risk assessment

中文摘要:

      目的 分析重庆市禽类产品中全氟和多氟烷基化合物(poly-and perfluoroalkyl substances, PFASs)的污染水平及赋存特征, 评估当地标准人通过禽类产品摄食PFASs的暴露风险。方法 以重庆市主城5区的禽类养殖场的6种禽类产品(鸡肉、鸡肝、鸡蛋、鸭肉、鸭肝、鸭蛋)为研究对象, 采用超高效液相色谱-串联质谱法(ultra performance liquid chromatography-tandem mass spectrometry, UPLC-MS/MS)对禽类产品中21种PFASs进行测定, 参考欧洲食品安全局的剂量值, 对当地一个标准人通过禽类产品摄入PFASs的健康暴露风险进行评估。结果 PFASs在禽类产品中普遍检出, 检出率为90.7%, 不同基质中全氟化合物总量呈现鸭肝(21.55 ng/g)>鸭蛋(19.28 ng/g)>鸡肝(15.28 ng/g)>鸡蛋(13.57 ng/g)>鸭肉(12.66 ng/g)>鸡肉(9.16 ng/g)的趋势, 并以中链PFASs检出为主, 其中全氟辛酸(perfluorooctanoic acid, PFOA)为主要污染物。基于主成分分析和Spearman相关性发现, 重庆市禽类产品中PFASs可能主要来自含氟化合物生产行业等的工业废水排放、氟调醇(fluorotelomer alcohols, PTOHs)降解和消费品。经估算, 当地一个标准人摄入上述禽类副产品中PFOA和全氟丁酸(perfluorobutanoic acid, PFBA)危害指数均大于1, 会对当地居民产生潜在危害。结论 本研究为重庆市禽类产品中PFASs监管提供数据支持, 同时对制定禽类产品的污染控制技术标准提供理论依据。

英文摘要:

      Objective To analyse the contamination level and composition characteristics of poly-and perfluoroalkyl substances (PFASs) in poultry products produced in Chongqing, and to evaluate the exposure risk of local standard man consuming PFASs from poultry products. Methods The 6 kinds of poultry products (chicken, chicken liver, henapple, duck, duck liver, duck egg) from poultry farms in 5 districts of Chongqing were selected as the research object. The concentrations of 21 kind of PFASs were determined by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The exposure risk of local adult men to PFASs from poultry products was assessed by referring to the dose value of European Food Safety Authority. Results The results showed that PFASs contamination was widespread in poultry products, the detection rate was 90.7%. PFAS concentrations varied across the products, with duck liver showing the highest levels (21.55 ng/g), followed by duck egg (19.28 ng/g), chicken liver (15.28 ng/g), hen egg (13.57 ng/g), duck meat (12.66 ng/g), and chicken meat (9.16 ng/g). Mid-chain PFASs were the main detected compound, in which perfluorooctanoic acid (PFOA) was the major pollutant. It was inferred that PFASs in the poultry products from Chongqing mainly came from consumer products, fluorotelomer alcohols (PTOHs) degradation and industrial wastewater emissions from fluorochemicals manufacturing industries based on the principal component analysis and Spearman correlation analysis. It was estimated that the harm index of PFOA and perfluorobutanoic acid (PFBA) in poultry products were greater than 1 for a local standard person, respectively. These were potentially harmful to the local population. Conclusion This study provides data support for the regulation of PFASs in poultry products, and theoretical basis for the formulation of the pollution control technical standards for poultry products.