国内外食品用菌种安全性法规和动物致病性评价方法对比研究

Comparative study on safety regulations and animal pathogenicity evaluation methods for strains used in food at home and abroad

中文关键词:  食品用菌种  安全性法规  动物致病性评价

英文关键词:strains used in food  safety regulations  animal pathogenicity evaluation

中文摘要:

      随着菌种在食品领域的广泛应用, 其安全性越来越受到重视。安全性评价包括国内外安全性评价资料、全基因组测序、动物致病性试验、耐药性试验等, 其中致病性是指微生物菌种感染宿主造成健康损害引起疾病的能力, 是菌种安全性评价的重要项目。本文系统地调研了国内外食品用菌种的安全性管理法规和动物致病性评价要求, 并对已报道的动物致病性评价方法进行了综合比较分析, 旨在为动物致病性评价在我国食品等领域菌株安全性评价中的应用奠定基础。

英文摘要:

      With the wide application of strains in food field, its safety has been paid more and more attention. Safety evaluation includes domestic and foreign safety evaluation data, whole genome sequencing, animal pathogenicity test, drug resistance test, etc. Among them, pathogenicity refers to the ability of microbial strains to infect the host and cause health damage and diseases, and is an important project of strain safety evaluation. The paper systematically investigated the safety management regulations and animal pathogenicity evaluation requirements of strains in food field at home and abroad, and conducted a comprehensive comparative analysis of the reported animal pathogenicity evaluation methods, aiming to lay a foundation for the application of animal pathogenicity evaluation in the safety evaluation of strains in food and other fields in China.