内蒙古部分地区鸡蛋中土霉素和强力霉素两种兽药残留检测及膳食风险评估

Detection and dietary risk assessment of two veterinary drugs, oxytetracycline and doxycycline, in eggs of Inner Mongolia

中文关键词:  鸡蛋  土霉素  强力霉素兽药残留  膳食暴露  风险评估

英文关键词:Eggs  oxytetracycline  doxycycline  veterinary drug residues  dietary exposure  risk assessment

中文摘要:

      目的 了解内蒙古自治区部分地区鸡蛋中2种兽药残留情况，并评估人体摄入健康风险。方法 在内蒙古自治区部分地区的农贸市场、商店、网店等采集共180份样品，采用液相色谱-串联质谱法(liquid chromatography-tandem mass spectrometry, LC-MS/MS)进行检测，分析鸡蛋中的土霉素、强力霉素残留含量，根据内蒙古居民的饮食消费情况，采用点评估法和食品安全指数法对鸡蛋中兽药的暴露风险进行评估。结果 2022—2023年内蒙古自治区部分地区土霉素、强力霉素总体样本检出率为23.89% (43/180)，超标率为12.22% (22/180)。强力霉素检出42份，检出率为23.33% (42/180)，超标率为12.22% (22/180)；土霉素检出3份，检出率为1.67% (3/180)，此次调查中无超标样本；鸡蛋中强力霉素食品安全指数均值为0.001851，最大值为0.2137，均小于1。结论 内蒙古自治区部分地区鸡蛋样本中存在少量的土霉素和强力霉素残留，暴露风险较低，对人体健康危害处在可接受范围。

英文摘要:

      Objective To understand the residues of 2 kinds of veterinary drugs in eggs in some areas of Inner Mongolia Autonomous Region, and to assess the health risk of human intake. Methods A total of 180 samples were collected from farmers’ markets, stores and online stores in some areas of Inner Mongolia Autonomous Region, and tested by liquid chromatography-tandem mass spectrometry (LC-MS/MS) to analyze the residual levels of tetracycline veterinary drugs in eggs, and to assess the exposure risk of veterinary drugs in eggs based on the dietary consumption of Inner Mongolia residents using the point assessment method and the food safety index method. Results The overall sample detection rate of oxytetracycline and doxycycline in some areas of Inner Mongolia Autonomous Region from 2022 to 2023 was 23.89% (43/180), and the over-standard rate was 12.22% (22/180). 42 doxycycline samples were detected, the detection rate was 23.33% (42/180), and the over-standard rate was 12.22% (22/180). 3samples of oxytetracycline were detected, the detection rate was 1.67% (3/180), and no samples exceeded the standard in this investigation; the mean value of the food safety index of doxycycline in eggs was 0.001851, and the maximum value was 0.2137, which were less than 1. Conclusion There were a small amount of oxytetracycline and doxycycline residues in egg samples in some areas of Inner Mongolia Autonomous Region, and the exposure risk was low, and the harm to human health was within the acceptable range.