基于适配体检测水果及其制品中棒曲霉素的研究进展

Research progress on aptamer-based detection of patulin in fruits and their products

中文关键词:  棒曲霉素  核酸适配体  适配体传感器  毒素检测

英文关键词:patulin  aptamers  aptamer sensors  toxin detection

中文摘要:

      棒曲霉素是广泛分布于各种水果、谷物及农产品中的一种真菌毒素, 在较低浓度下产生持久性的毒性作用, 对人类和动物健康造成严重的危害。随着人们对食品安全关注度的增加, 棒曲霉素在水果及其制品中快速检测方法的研究引发广泛关注。适配体传感器因灵敏度高、耗时短、易操作及开发成本低等优点, 在毒素快速检测方面具有潜在的开发和应用优势。本综述从棒曲霉素适配体筛选入手, 着重介绍了基于电化学、光学和光电化学原理的适配体传感器在检测毒素中的原理、策略和应用, 并展开分析其当前的发展现状、局限性和未来发展前景, 旨在对水果及其制品中棒曲霉素有效检测和风险评估提供有益的见解, 为棒曲霉素快速检测方法的研究和发展提供一定参考。

英文摘要:

      Patulin is a mycotoxin widely distributed in various fruits, grains and agricultural products, which produces persistent toxic effects at low concentrations and poses serious health hazards to humans and animals. With the increasing concern for food safety, the study of rapid detection methods for patulin in fruits and their products has attracted much attention. Aptamer sensors have potential advantages in the development and application of rapid toxin detection due to their high sensitivity, short time-consumption, ease of operation and low development cost. Starting from the screening of patulin aptamers, this review focused on the principles, strategies and applications of aptamer sensors based on electrochemical, optical and photoelectrochemical principles in the detection of toxins, and analyzed their current development status, limitations and future development prospects, aiming to provide useful insights for the effective detection and risk assessment of patulin in fruits and their products, and provide a reference for the research and development of rapid detection methods for patulin.