萝卜硫素对肥胖的干预作用研究进展

Research progress on the interventional effects of sulforaphane on obesity

中文关键词:  萝卜硫素  肥胖  脂质代谢  机制研究

英文关键词:sulforaphane  obesity  lipid metabolism  mechanistic studies

中文摘要:

      萝卜硫素又称莱菔硫烷, 广泛存在于十字花科蔬菜中, 具有抗菌、抗炎、降低心脑血管风险等功效。同时, 萝卜硫素也是蔬菜中抗癌效果最好的天然活性物质之一, 能够有效抑制乳腺癌、肝癌等。随着生活水平的提高, 我国肥胖患病率逐年增长。现有研究发现萝卜硫素能够通过调节脂质代谢, 影响脂肪细胞合成, 改善氧化应激水平及调节肠道菌群等多种途径改善调控肥胖, 是一种潜在预防或治疗肥胖症的辅助剂。本文结合国内外相关研究对萝卜硫素在肥胖领域的机制进行了系统介绍, 为萝卜硫素的科学研究及膳食应用提供参考。

英文摘要:

      Sulforaphane is widely found in cruciferous vegetables, with antibacterial, anti-inflammatory and cardiovascular risk reduction effects. At the same time, sulforaphane is also one of the best natural active substances in vegetables with anti-cancer effect, which can effectively inhibit breast cancer, liver cancer and so on. With the improvement of living standards, the prevalence of obesity in China is increasing year by year. Existing studies have found that sulforaphane can improve the regulation of obesity by regulating lipid metabolism, affecting the synthesis of adipocytes, improve oxidative stress levels and regulating intestinal flora, which is a kind of potential auxiliary agent for the prevention or treatment of obesity. This paper systematically introduced the function of sulforaphane in the field of obesity with domestic and foreign related research, which provides reference for the scientific research and dietary application of sulforaphane.