红芪活性成分免疫调节作用及机制研究进展

Research progress on immunoregulatory effect and mechanism of active components of Hedysari radix

中文关键词:  红芪  活性成分  免疫调节

英文关键词:Hedysari radix  active ingredients  immunomodulation

中文摘要:

      免疫功能受损或免疫系统紊乱会导致机体疾病发生, 基于调节机体免疫治疗疾病已成为临床应用 热点。红芪活性成分主要有红芪多糖、黄酮类、萜类、皂苷类等, 其中红芪多糖为红芪发挥免疫调节作用 的主要物质基础。免疫调节是机体通过免疫系统来调节、平衡自身及外来抗原识别和应答的过程, 使其能 够适应不同外界刺激和病理状态, 从而维持机体的健康。红芪增强机体免疫力主要体现在增强免疫器官功 能, 诱导免疫细胞分化、促进免疫因子分泌, 提高单核巨噬细胞吞噬功能、调节炎性因子水平以及激活相关 通路等方面。本文主要阐述红芪活性物质免疫调节作用机制, 以期为红芪在食品、药品保健等领域的开发 应用提供思路。

英文摘要:

      Impaired immune function or immune system disorders always lead to the occurrence of diseases, and regulating the body’s immune therapy has become a hot topic in clinical applications. The active components of Hedysari radix mainly include polysaccharides, flavonoids, terpenoids, saponins, etc.. among them, polysaccharides are the main material basis for Hedysari radix to play an immunomodulatory role. Immune regulation is the process by which the body regulates and balances its own and foreign antigen recognition and response through the immune system, enabling it to adapt to different external stimuli and pathological states, thereby maintaining the health of the body. Hedysari radix enhances the body’s immune system mainly by enhancing the function of immune organs, inducing immune cell differentiation, promoting immune factor secretion, improving the phagocytic function of monocytes and macrophages, regulating inflammatory factor levels, and activating related pathways. This article mainly expounded the active substances of Hedysari radix, which provide ideas for the development and application of Hedysari radix in the fields of food, medicine, and health care.